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The map label for this gene is codA [H]

Identifier: 119900058

GI number: 119900058

Start: 4129784

End: 4131070

Strand: Direct

Name: codA [H]

Synonym: azo3769

Alternate gene names: 119900058

Gene position: 4129784-4131070 (Clockwise)

Preceding gene: 119900056

Following gene: 119900059

Centisome position: 94.37

GC content: 71.79

Gene sequence:

>1287_bases
ATGCTCGATCTCGTGCTACGCAACTGCACCCTGCCCGACGGCCGCCAAGGCCTCGACATCGGCATCGCCGGTGGCCGCAT
CGTCGCCGTCGAGCCGGCCCTCGCCGCCAGTGCGGCCCAGACCCTGGACGCCGCCGGCCAGCTCGTCAGCCCGCCCTTCG
TCGACGCCCACTTCCACATGGACGCCACCCTGTCCTACGGCCTGCCGCGGGTGAATGCCTCCGGCACCCTGCTCGAAGGC
ATCGCGCTGTGGGGCGAACTCAAACCCCAGCTCACGCAGGAGGCGCTGGTGGAGCGCGCGCTCGCCTACTGCGACTGGGC
GGTGGCCAAGGGCCTGCTGGCGATCCGCAGCCATGTCGACGTGTGCGATCCGCGGCTGTTGGCGGTGGAGGCGCTGCTGC
ACGTGAAGGAGACGGTGAAGCCCTGGCTAGACCTGCAGCTGGTCGCCTTCCCGCAGGACGGCGTGCTGCGCAGCCCCGGC
GCGCTTGCCAACCTGGAGCGCGCGCTGGAGATGGGCGTGGAGGTGGTCGGCGGCATCCCGCACTTCGAGCGCACCATGGC
CGACGGCGCGGAATCGGTGCGCATCCTGTGCGAACTCGCCGCCCGCCGCGGGCTGCGGGTGGATATGCACTGCGACGAAT
CCGACGACCCGCACTCGCGCCACATCGAGACGCTGGCCTTTCATGCCCAGCGCCTGGGGCTGCAGGGCCGCGTCACCGGC
TCGCACCTCACCTCCATGCACTCGATGGACAACTACTACGTCTCCAAGCTGCTGCCGCTGATGGCGGAAGCCGGCGTCGC
CGCCGTCGCCAACCCGCTGATCAACATCACGCTGCAGGGCCGCCACGACAGCTACCCCAAGCGCCGCGGCATGACGCGGG
TGCCGGAACTGCTCGCCGCCGGCATCCCGGTCGCGTTCGGTCACGACTGCGTGATGGACCCCTGGTACAGCCTGGGCAGC
GGCGACATGCTGGAAGTGGCGCACATGGGCCTGCATGTGGCGCAGATGACCGGGCAGGCGGCGATGCACGCCTGCTTCCG
CGCCGTCACCGAAACTCCCGCGGCCGTACTCGGCCTGGAAGGCTACGGCCTGGCACCGGGCTGCCGCGCCGACCTGGTGC
TGCTGCAGGCGCGCGACCCGATCGAGGCGATCCGGCTGCGCGCCACCCGGCTGGCGGTGGTGCGCGGCGGGCGCGTCGTC
GCGCGCACGCCGGCGGCCGTGGCCACGCTGGACCTGCCCGGGCGGCCGTCGACGACCACCTGGCAGCTGCCGCCACGCAG
CGATTGA

Upstream 100 bases:

>100_bases
GGCGCTCCTGCAACCGGTGTTCCTGTCGCGCAGCGGTTTGCGCGCCGCCGCGCGGCGGGTTAAAAACGCCCAGGCGCTGC
ACATCCTGTCCGGAGTTCCC

Downstream 100 bases:

>100_bases
GCGGGCGGACACCCCGGCGCCGCCAGTTTGATTGCCGGCTCGGCAGGCGGGCGCCGGGTTTGCTGCGCTTCCGTCAGCGC
CGCGTTGTCCGCAGCGGGCG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLDLVLRNCTLPDGRQGLDIGIAGGRIVAVEPALAASAAQTLDAAGQLVSPPFVDAHFHMDATLSYGLPRVNASGTLLEG
IALWGELKPQLTQEALVERALAYCDWAVAKGLLAIRSHVDVCDPRLLAVEALLHVKETVKPWLDLQLVAFPQDGVLRSPG
ALANLERALEMGVEVVGGIPHFERTMADGAESVRILCELAARRGLRVDMHCDESDDPHSRHIETLAFHAQRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMAEAGVAAVANPLINITLQGRHDSYPKRRGMTRVPELLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQAAMHACFRAVTETPAAVLGLEGYGLAPGCRADLVLLQARDPIEAIRLRATRLAVVRGGRVV
ARTPAAVATLDLPGRPSTTTWQLPPRSD

Sequences:

>Translated_428_residues
MLDLVLRNCTLPDGRQGLDIGIAGGRIVAVEPALAASAAQTLDAAGQLVSPPFVDAHFHMDATLSYGLPRVNASGTLLEG
IALWGELKPQLTQEALVERALAYCDWAVAKGLLAIRSHVDVCDPRLLAVEALLHVKETVKPWLDLQLVAFPQDGVLRSPG
ALANLERALEMGVEVVGGIPHFERTMADGAESVRILCELAARRGLRVDMHCDESDDPHSRHIETLAFHAQRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMAEAGVAAVANPLINITLQGRHDSYPKRRGMTRVPELLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQAAMHACFRAVTETPAAVLGLEGYGLAPGCRADLVLLQARDPIEAIRLRATRLAVVRGGRVV
ARTPAAVATLDLPGRPSTTTWQLPPRSD
>Mature_428_residues
MLDLVLRNCTLPDGRQGLDIGIAGGRIVAVEPALAASAAQTLDAAGQLVSPPFVDAHFHMDATLSYGLPRVNASGTLLEG
IALWGELKPQLTQEALVERALAYCDWAVAKGLLAIRSHVDVCDPRLLAVEALLHVKETVKPWLDLQLVAFPQDGVLRSPG
ALANLERALEMGVEVVGGIPHFERTMADGAESVRILCELAARRGLRVDMHCDESDDPHSRHIETLAFHAQRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMAEAGVAAVANPLINITLQGRHDSYPKRRGMTRVPELLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQAAMHACFRAVTETPAAVLGLEGYGLAPGCRADLVLLQARDPIEAIRLRATRLAVVRGGRVV
ARTPAAVATLDLPGRPSTTTWQLPPRSD

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=408, Percent_Identity=46.3235294117647, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1786517, Length=399, Percent_Identity=27.5689223057644, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 45893; Mature: 45893

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLVLRNCTLPDGRQGLDIGIAGGRIVAVEPALAASAAQTLDAAGQLVSPPFVDAHFHM
CCCEEEECCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
DATLSYGLPRVNASGTLLEGIALWGELKPQLTQEALVERALAYCDWAVAKGLLAIRSHVD
CCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VCDPRLLAVEALLHVKETVKPWLDLQLVAFPQDGVLRSPGALANLERALEMGVEVVGGIP
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
HFERTMADGAESVRILCELAARRGLRVDMHCDESDDPHSRHIETLAFHAQRLGLQGRVTG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SHLTSMHSMDNYYVSKLLPLMAEAGVAAVANPLINITLQGRHDSYPKRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GIPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGQAAMHACFRAVTETPAAVLGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECC
GYGLAPGCRADLVLLQARDPIEAIRLRATRLAVVRGGRVVARTPAAVATLDLPGRPSTTT
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCEEEEECCCEEEEEECCCCCCCCE
WQLPPRSD
ECCCCCCC
>Mature Secondary Structure
MLDLVLRNCTLPDGRQGLDIGIAGGRIVAVEPALAASAAQTLDAAGQLVSPPFVDAHFHM
CCCEEEECCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
DATLSYGLPRVNASGTLLEGIALWGELKPQLTQEALVERALAYCDWAVAKGLLAIRSHVD
CCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VCDPRLLAVEALLHVKETVKPWLDLQLVAFPQDGVLRSPGALANLERALEMGVEVVGGIP
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
HFERTMADGAESVRILCELAARRGLRVDMHCDESDDPHSRHIETLAFHAQRLGLQGRVTG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SHLTSMHSMDNYYVSKLLPLMAEAGVAAVANPLINITLQGRHDSYPKRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GIPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGQAAMHACFRAVTETPAAVLGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECC
GYGLAPGCRADLVLLQARDPIEAIRLRATRLAVVRGGRVVARTPAAVATLDLPGRPSTTT
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCEEEEECCCEEEEEECCCCCCCCE
WQLPPRSD
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]