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The map label for this gene is cbiC [H]

Identifier: 119899820

GI number: 119899820

Start: 3875800

End: 3876477

Strand: Direct

Name: cbiC [H]

Synonym: azo3531

Alternate gene names: 119899820

Gene position: 3875800-3876477 (Clockwise)

Preceding gene: 119899819

Following gene: 119899821

Centisome position: 88.57

GC content: 70.5

Gene sequence:

>678_bases
ATGAGCACCGCCAACACCGTCACCGAACAGCTCACCGCCGCCGGCCGCGCCATCGAGCACGACTCCTTCGCCATCATCGA
CGCCGAGGTCGGCGCCCATGCCTACAGCGCGGAGCAGTGGCCGATCGTCCGCCGCATGATCCACGCCAATGCCGACTTCG
AGTTCAACGGCCTCACCGACTTCCACCCCGCGGCGGTCGAAGCCGGGCTCGCCGCCATCCTCGGCGGCGGCTCGCGGGTG
GTGGCCGATGTCGAGATGATCTGCGTCGGCCTGTCGGCCTCGCGCCTGGCGCACTTCGGCATCAGCACCCACCAGTTCAT
TTCCGATACCGACGTCATCGCCCGCGCGAAGGCGGAGGAGACCACGCGCGCGGTGCAGGCGATGCGCAAGGCGCACCGGC
TGGGATTGATCAACGGCGCCCTCGTCGGCATCGGCAACGCTCCCACCGCGCTGATCGAGCTGGTACGGCTGATCCGCGAG
GAAGGCGCGCGCCCGGCGCTGGTGGTCGGCATGCCGGTGGGCTTCGTCTCGGCGGCGGAATCCAAGGACCTGATGGCCGG
ACTCGACGACGTGCCGTGGATCGTGATCCGCGGCCGCAAGGGCGGCTCGACGCTGGTGGTCGCGGCGATCCACGCCCTGC
TCGGGCTGGCCGAAGCGCGCCAGCGCGAAGGGCGCTGA

Upstream 100 bases:

>100_bases
CCATGTGCATGACGACCATGGCGATCACGGTCACGCCCACCAAGGCCATGACCACGGCCACGACGGCCATCACCACCACG
ATCACGCCCACGCCTGAAGC

Downstream 100 bases:

>100_bases
GCCGATGAGCACCGGCCACGCGCTTTCGCCGGCGTCCCAGGAGAAGATCCGCAAGGGCGACCCCAAGCGCGACCGCGGCA
ACCGCAGCGGCTTTTCCACC

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSTANTVTEQLTAAGRAIEHDSFAIIDAEVGAHAYSAEQWPIVRRMIHANADFEFNGLTDFHPAAVEAGLAAILGGGSRV
VADVEMICVGLSASRLAHFGISTHQFISDTDVIARAKAEETTRAVQAMRKAHRLGLINGALVGIGNAPTALIELVRLIRE
EGARPALVVGMPVGFVSAAESKDLMAGLDDVPWIVIRGRKGGSTLVVAAIHALLGLAEARQREGR

Sequences:

>Translated_225_residues
MSTANTVTEQLTAAGRAIEHDSFAIIDAEVGAHAYSAEQWPIVRRMIHANADFEFNGLTDFHPAAVEAGLAAILGGGSRV
VADVEMICVGLSASRLAHFGISTHQFISDTDVIARAKAEETTRAVQAMRKAHRLGLINGALVGIGNAPTALIELVRLIRE
EGARPALVVGMPVGFVSAAESKDLMAGLDDVPWIVIRGRKGGSTLVVAAIHALLGLAEARQREGR
>Mature_224_residues
STANTVTEQLTAAGRAIEHDSFAIIDAEVGAHAYSAEQWPIVRRMIHANADFEFNGLTDFHPAAVEAGLAAILGGGSRVV
ADVEMICVGLSASRLAHFGISTHQFISDTDVIARAKAEETTRAVQAMRKAHRLGLINGALVGIGNAPTALIELVRLIREE
GARPALVVGMPVGFVSAAESKDLMAGLDDVPWIVIRGRKGGSTLVVAAIHALLGLAEARQREGR

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23704; Mature: 23572

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTANTVTEQLTAAGRAIEHDSFAIIDAEVGAHAYSAEQWPIVRRMIHANADFEFNGLTD
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEECCCCC
FHPAAVEAGLAAILGGGSRVVADVEMICVGLSASRLAHFGISTHQFISDTDVIARAKAEE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHH
TTRAVQAMRKAHRLGLINGALVGIGNAPTALIELVRLIREEGARPALVVGMPVGFVSAAE
HHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCC
SKDLMAGLDDVPWIVIRGRKGGSTLVVAAIHALLGLAEARQREGR
CHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STANTVTEQLTAAGRAIEHDSFAIIDAEVGAHAYSAEQWPIVRRMIHANADFEFNGLTD
CCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEECCCCC
FHPAAVEAGLAAILGGGSRVVADVEMICVGLSASRLAHFGISTHQFISDTDVIARAKAEE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHH
TTRAVQAMRKAHRLGLINGALVGIGNAPTALIELVRLIREEGARPALVVGMPVGFVSAAE
HHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCC
SKDLMAGLDDVPWIVIRGRKGGSTLVVAAIHALLGLAEARQREGR
CHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]