Click here to switch to the map view.

The map label for this gene is coxM [H]

Identifier: 119870719

GI number: 119870719

Start: 4915549

End: 4916439

Strand: Direct

Name: coxM [H]

Synonym: Mkms_4690

Alternate gene names: 119870719

Gene position: 4915549-4916439 (Clockwise)

Preceding gene: 119870718

Following gene: 119870720

Centisome position: 85.68

GC content: 70.03

Gene sequence:

>891_bases
ATGAAGGCCGCCCCGTTCGCCTACCACCGCCCGGATTCGGTGACCGAGGCGGTGCAGATGCTGTCCGAGTTCGGCGACGA
CGCGAAGATCCTCGCCGGCGGGCAGAGCCTGGTGCCGATGCTGGCCATGCGGCTGACGCACTTCGAGCACCTCATCGACA
TCTCCCGGATCGGCGAGTTGACGGGTATCGACCTCGTCGACGGTCAGATCGTGGTGCGCGCGGCGACGCCGCACGCGTTG
GTCGGTTTGGACGACGAGGTCGCCGACTCGGTGCCGCTGCTGACGCTGGCCACCCCGCACATCGGGCACTTCCAGATCCG
CACGCGCGGCACTCTCGGCGGGGCGATCGCGCACGCCGACCCCGCGGCCGAATACGCCGCCGTCGCACTGGCACTCGACG
CTCAGATCGAGGCCGTGTCCAGCCGTGGCCGACGGGACATCGCCGCGGCCGACCTCTTCACCGGCCTGTGGGAGACGTCG
CTCGCGGCCGACGAGATCCTCACCGCCGTGCGGTTCCCGGTGTGGAGCGGCCGGTGCGGCTTCGCCGTCGAGGAATTCGC
CCGTAGGCACGGAGATTTCGCGATCGCCGGTGCGACGGTCGCGCTCGAACTCGACGGCGACGACCGGGTGACGCGCTGCG
CCATCGGGCTACTGGGGCTGGGGTCGACCCCGCTGCGCGGTGTCGACGGTGAACAAGCCGTCGTCGGCACTCGGGTCTCA
GACATCAGCACCGACGAGATCGGCAGGCTCACGCTGGCCGCTGTGACGGACGTGCCCGCCGACCTTCAAGGTTCGGCGAG
CTATCGGCGCCGGGTCGGCGCCGCGATGGTCTCGCGTGCCCTGGCATCGGCGGTCGCCCAGGTGACTTCGGAGGAGATGA
TCCATGCATGA

Upstream 100 bases:

>100_bases
GCCGCAGGCGCGCGCATCCGGCCGCGGTGTTGGCCGAGGATCTGCAGGCCGCGCTGGCCCGCCTGCTCGGCCCGTTGTCG
CCGGCCGACCGGCTCCGGCC

Downstream 100 bases:

>100_bases
GTTGCCGGTCGAGTTGACGGTCAACGGCCGCAACCATCGCGGAGTGGTGGAGCCGCGTATCACGTTGGCCGACTTCCTGC
GCGAGACATGCGGTCTCACC

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKAAPFAYHRPDSVTEAVQMLSEFGDDAKILAGGQSLVPMLAMRLTHFEHLIDISRIGELTGIDLVDGQIVVRAATPHAL
VGLDDEVADSVPLLTLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAQIEAVSSRGRRDIAAADLFTGLWETS
LAADEILTAVRFPVWSGRCGFAVEEFARRHGDFAIAGATVALELDGDDRVTRCAIGLLGLGSTPLRGVDGEQAVVGTRVS
DISTDEIGRLTLAAVTDVPADLQGSASYRRRVGAAMVSRALASAVAQVTSEEMIHA

Sequences:

>Translated_296_residues
MKAAPFAYHRPDSVTEAVQMLSEFGDDAKILAGGQSLVPMLAMRLTHFEHLIDISRIGELTGIDLVDGQIVVRAATPHAL
VGLDDEVADSVPLLTLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAQIEAVSSRGRRDIAAADLFTGLWETS
LAADEILTAVRFPVWSGRCGFAVEEFARRHGDFAIAGATVALELDGDDRVTRCAIGLLGLGSTPLRGVDGEQAVVGTRVS
DISTDEIGRLTLAAVTDVPADLQGSASYRRRVGAAMVSRALASAVAQVTSEEMIHA
>Mature_296_residues
MKAAPFAYHRPDSVTEAVQMLSEFGDDAKILAGGQSLVPMLAMRLTHFEHLIDISRIGELTGIDLVDGQIVVRAATPHAL
VGLDDEVADSVPLLTLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAQIEAVSSRGRRDIAAADLFTGLWETS
LAADEILTAVRFPVWSGRCGFAVEEFARRHGDFAIAGATVALELDGDDRVTRCAIGLLGLGSTPLRGVDGEQAVVGTRVS
DISTDEIGRLTLAAVTDVPADLQGSASYRRRVGAAMVSRALASAVAQVTSEEMIHA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=284, Percent_Identity=29.2253521126761, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 31084; Mature: 31084

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAPFAYHRPDSVTEAVQMLSEFGDDAKILAGGQSLVPMLAMRLTHFEHLIDISRIGEL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
TGIDLVDGQIVVRAATPHALVGLDDEVADSVPLLTLATPHIGHFQIRTRGTLGGAIAHAD
CCCEEECCEEEEEECCCCEEECCCHHHHCCCCEEEEECCCCCEEEEEECCCCCCHHHCCC
PAAEYAAVALALDAQIEAVSSRGRRDIAAADLFTGLWETSLAADEILTAVRFPVWSGRCG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FAVEEFARRHGDFAIAGATVALELDGDDRVTRCAIGLLGLGSTPLRGVDGEQAVVGTRVS
HHHHHHHHHCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
DISTDEIGRLTLAAVTDVPADLQGSASYRRRVGAAMVSRALASAVAQVTSEEMIHA
CCCCCHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAAPFAYHRPDSVTEAVQMLSEFGDDAKILAGGQSLVPMLAMRLTHFEHLIDISRIGEL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
TGIDLVDGQIVVRAATPHALVGLDDEVADSVPLLTLATPHIGHFQIRTRGTLGGAIAHAD
CCCEEECCEEEEEECCCCEEECCCHHHHCCCCEEEEECCCCCEEEEEECCCCCCHHHCCC
PAAEYAAVALALDAQIEAVSSRGRRDIAAADLFTGLWETSLAADEILTAVRFPVWSGRCG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FAVEEFARRHGDFAIAGATVALELDGDDRVTRCAIGLLGLGSTPLRGVDGEQAVVGTRVS
HHHHHHHHHCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
DISTDEIGRLTLAAVTDVPADLQGSASYRRRVGAAMVSRALASAVAQVTSEEMIHA
CCCCCHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 1510563; 2818128; 10430865; 12475995 [H]