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The map label for this gene is baeB [H]

Identifier: 119866983

GI number: 119866983

Start: 1018738

End: 1019454

Strand: Reverse

Name: baeB [H]

Synonym: Mkms_0931

Alternate gene names: 119866983

Gene position: 1019454-1018738 (Counterclockwise)

Preceding gene: 119866994

Following gene: 119866982

Centisome position: 17.77

GC content: 68.62

Gene sequence:

>717_bases
GTGTCGAATTCCGAACGTCTCTACTTCCGCCAGCTGCTCGCCGGCCGCGACTTCGCCGTCGGCGACATGATCGCCACGCA
GATGCGCAACTTCGCCTACCTCATCGGCGACCGGGAGACCGGCGACTGCGTCGTCGTCGATCCGGCCTACGCCGCCGGTG
ATCTGGTCGACGCGCTGGAGGCCGACGGCATGCACCTGTCCGGTGTGTTGGCGACTCACCACCACCCCGACCACGTCGGC
GGTTCGATGATGGGCTTCGAGCTCAAGGGGCTGGCCGAACTGCTCGAGCGGGTCAGCGTGCCGGTGCATGTGAACAGCCA
TGAGGCCGACTGGGTTTCGCGGGTCACCGGAATCGCCCGCAGCGAGCTGACCGCCCACGACCACGGGGATGTGGTCAGCG
TCGGCGGTATCGACATCGAACTGCTGCACACCCCCGGGCACACGCCGGGCAGCCAGTGCTTCCTGCTCGACGGCCGGCTG
GTCGCCGGGGACACGCTGTTCCTCGAGGGTTGCGGCCGCACCGACTTCCCGGGCGGGAACGTCGACGACATGTTCCGCAG
CCTGCAGGCCCTGGCTCAGCTGCCCGGCGACCCGACGGTGTTCCCCGGGCACTGGTACTCCGCGGAGCCGAGCGACGCCC
TGTCGAACGTCAAGCGGTCGAACTACGTCTACCGCGCCCGCGACCTCGACCAGTGGCGCATGTTGATGGGCGGCTGA

Upstream 100 bases:

>100_bases
ACGCTATGTAAATGCGTAGATCAGACGCCACTTTTGCGGGTGTGCCCTTAAACACCCCGCGACGTGCGGTTTTTTCACCA
GCCGCTTTAGGCTGTGGGAC

Downstream 100 bases:

>100_bases
GCTCGAAACTGAACTCACGCAGGCTTGCTCTCGCAGTTCCGCTGCGTGGCTTCAGCCTGGCGGCACGGGTGGGGTGGAGC
TCCGCGTCGCCAACACGAGA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSNSERLYFRQLLAGRDFAVGDMIATQMRNFAYLIGDRETGDCVVVDPAYAAGDLVDALEADGMHLSGVLATHHHPDHVG
GSMMGFELKGLAELLERVSVPVHVNSHEADWVSRVTGIARSELTAHDHGDVVSVGGIDIELLHTPGHTPGSQCFLLDGRL
VAGDTLFLEGCGRTDFPGGNVDDMFRSLQALAQLPGDPTVFPGHWYSAEPSDALSNVKRSNYVYRARDLDQWRMLMGG

Sequences:

>Translated_238_residues
MSNSERLYFRQLLAGRDFAVGDMIATQMRNFAYLIGDRETGDCVVVDPAYAAGDLVDALEADGMHLSGVLATHHHPDHVG
GSMMGFELKGLAELLERVSVPVHVNSHEADWVSRVTGIARSELTAHDHGDVVSVGGIDIELLHTPGHTPGSQCFLLDGRL
VAGDTLFLEGCGRTDFPGGNVDDMFRSLQALAQLPGDPTVFPGHWYSAEPSDALSNVKRSNYVYRARDLDQWRMLMGG
>Mature_237_residues
SNSERLYFRQLLAGRDFAVGDMIATQMRNFAYLIGDRETGDCVVVDPAYAAGDLVDALEADGMHLSGVLATHHHPDHVGG
SMMGFELKGLAELLERVSVPVHVNSHEADWVSRVTGIARSELTAHDHGDVVSVGGIDIELLHTPGHTPGSQCFLLDGRLV
AGDTLFLEGCGRTDFPGGNVDDMFRSLQALAQLPGDPTVFPGHWYSAEPSDALSNVKRSNYVYRARDLDQWRMLMGG

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=181, Percent_Identity=33.7016574585635, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI116642887, Length=210, Percent_Identity=34.7619047619048, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI21703352, Length=213, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI94538320, Length=209, Percent_Identity=29.6650717703349, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI94538322, Length=209, Percent_Identity=29.6650717703349, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI46361987, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI14150041, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=194, Percent_Identity=31.9587628865979, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786406, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538952, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17536925, Length=188, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320478, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356335, Length=206, Percent_Identity=30.5825242718447, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24667703, Length=206, Percent_Identity=30.5825242718447, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667711, Length=206, Percent_Identity=30.5825242718447, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221330176, Length=245, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 25861; Mature: 25730

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSERLYFRQLLAGRDFAVGDMIATQMRNFAYLIGDRETGDCVVVDPAYAAGDLVDALE
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCHHHHHHHHHHH
ADGMHLSGVLATHHHPDHVGGSMMGFELKGLAELLERVSVPVHVNSHEADWVSRVTGIAR
CCCCEEEEEEEECCCCCCCCCCEECEEHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
SELTAHDHGDVVSVGGIDIELLHTPGHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFPGGN
HHCCCCCCCCEEEECCEEEEEEECCCCCCCCEEEEECCEEEECCEEEEECCCCCCCCCCC
VDDMFRSLQALAQLPGDPTVFPGHWYSAEPSDALSNVKRSNYVYRARDLDQWRMLMGG
HHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHCC
>Mature Secondary Structure 
SNSERLYFRQLLAGRDFAVGDMIATQMRNFAYLIGDRETGDCVVVDPAYAAGDLVDALE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCHHHHHHHHHHH
ADGMHLSGVLATHHHPDHVGGSMMGFELKGLAELLERVSVPVHVNSHEADWVSRVTGIAR
CCCCEEEEEEEECCCCCCCCCCEECEEHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
SELTAHDHGDVVSVGGIDIELLHTPGHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFPGGN
HHCCCCCCCCEEEECCEEEEEEECCCCCCCCEEEEECCEEEECCEEEEECCCCCCCCCCC
VDDMFRSLQALAQLPGDPTVFPGHWYSAEPSDALSNVKRSNYVYRARDLDQWRMLMGG
HHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA