BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is ydfG [C]

Identifier: 119866722

GI number: 119866722

Start: 723428

End: 724183

Strand: Reverse

Name: ydfG [C]

Synonym: Mkms_0668

Alternate gene names: 119866722

Gene position: 724183-723428 (Counterclockwise)

Preceding gene: 119866729

Following gene: 119866719

Centisome position: 12.62

GC content: 68.78

Gene sequence:

>756_bases
ATGACGACATCTCGAGGCGACCAACGCGTCGCGGTGGTCACCGGCGCCAGCGCCGGTATCGGCGAGGCGACCGCGAGAAC
CCTTGCCGCCCAAGGCTTTCACGTGGTCTGCGTGGCCCGCCGAGAGGAACCCATCAAGGCTCTCGCCGACGAGATCGGCG
GGACCGCCGTTGTGGCGGACGTCACGTCCACCGAGGCGGTGGACGCATTGGCCGCGGCGCTGGACCGGGTGGATGTGCTG
GTCAACAACGCCGGCGGCGCCCGCGGGCTGGACCCGATCGCCGAAGCCGACATCGAGCACTGGCGGTGGATGTGGGAGTC
AAACGTGCTCGGCACGCTGCTGGTGACCCGCGCGCTGCTGCCGAAGCTCATCGACTCCGGTGACGGGCTGATCGTCACGG
TCACCTCCATCGCCGCGGTGGAGATCTACGACAACGGTGGCGGCTACACCTCGGCCAAACACGCCCAGGGGGTCCTGCAC
CGCACGCTGCGCAGCGAGCTGCTCGGAAAACCGGTGCGGCTCACCGAGGTTGCGCCCGGCATGGTGAAGACGGACTTCTC
GCTCAACCGGTTCGAGGGCGACGAAGAGCGCGCCGAGAAGGTCTACGAGGGGGTCACCCCGCTGGTCGCCGAGGACATCG
CCGAGGTGATCGGATTCGTCGCCAGCCGGCCCTCGCACGTCGACCTGGACCTGATTGTGATCCGGCCGCGCGATCAGGTC
AGCGGCGCCAGCGGCTCACGTTTCAACCGCCGCTGA

Upstream 100 bases:

>100_bases
CGCGGCGAAATGCGCAACGACAACAACAGTGCCGCGCGTCGAAGACCTGACCACCGGAGAACACGAGAGTGAATCTAGCA
CGCTGGCTAGAGTTGGGCAG

Downstream 100 bases:

>100_bases
CGGCGGGGCTACCCGCCGGGGCGGCCGTTGACCGGCTGCGGTGCGCCGGTCGGGGTCACCGGTGCGGTGCTCGGGATGCC
CGCCGGCGACGCCTGATCCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVADVTSTEAVDALAAALDRVDVL
VNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALLPKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLH
RTLRSELLGKPVRLTEVAPGMVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV
SGASGSRFNRR

Sequences:

>Translated_251_residues
MTTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVADVTSTEAVDALAAALDRVDVL
VNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALLPKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLH
RTLRSELLGKPVRLTEVAPGMVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV
SGASGSRFNRR
>Mature_250_residues
TTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVADVTSTEAVDALAAALDRVDVLV
NNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALLPKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLHR
TLRSELLGKPVRLTEVAPGMVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQVS
GASGSRFNRR

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=254, Percent_Identity=33.0708661417323, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=29.1304347826087, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=230, Percent_Identity=31.304347826087, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=231, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=33.1658291457286, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=35.2331606217617, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI40548397, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010158, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010156, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22758144, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=31.7708333333333, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI19923817, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=180, Percent_Identity=32.7777777777778, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI66933014, Length=228, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=35.8649789029536, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1787335, Length=229, Percent_Identity=32.3144104803493, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=190, Percent_Identity=35.7894736842105, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=30.6878306878307, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082100, Length=192, Percent_Identity=34.8958333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788459, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787526, Length=214, Percent_Identity=27.5700934579439, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=28.8617886178862, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=32.3886639676113, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=247, Percent_Identity=31.9838056680162, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=200, Percent_Identity=30, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=189, Percent_Identity=34.3915343915344, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=236, Percent_Identity=31.3559322033898, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=243, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=29.2887029288703, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=256, Percent_Identity=30.078125, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=251, Percent_Identity=29.0836653386454, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=189, Percent_Identity=32.2751322751323, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=28.0155642023346, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=247, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=245, Percent_Identity=30.2040816326531, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=249, Percent_Identity=29.3172690763052, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=27.8008298755187, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=206, Percent_Identity=30.0970873786408, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=29.5546558704453, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=255, Percent_Identity=29.0196078431373, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=245, Percent_Identity=28.9795918367347, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=34.6774193548387, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=31.25, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007236, Length=247, Percent_Identity=32.7935222672065, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=33.984375, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=33.984375, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=226, Percent_Identity=32.7433628318584, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641388, Length=248, Percent_Identity=32.258064516129, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=32.156862745098, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=28.1938325991189, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281364494, Length=254, Percent_Identity=27.9527559055118, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571387, Length=252, Percent_Identity=28.968253968254, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=231, Percent_Identity=32.9004329004329, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648944, Length=248, Percent_Identity=30.241935483871, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116007234, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=232, Percent_Identity=31.8965517241379, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24663911, Length=253, Percent_Identity=29.2490118577075, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.7708333333333, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.7708333333333, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=33.5227272727273, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580925, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=239, Percent_Identity=33.0543933054393, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=31.413612565445, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26648; Mature: 26517

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVAD
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCEEEEEE
VTSTEAVDALAAALDRVDVLVNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALL
CCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
PKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG
HHHHCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
MVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV
CEECCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
SGASGSRFNRR
CCCCCCCCCCC
>Mature Secondary Structure 
TTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVAD
CCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCEEEEEE
VTSTEAVDALAAALDRVDVLVNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALL
CCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
PKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG
HHHHCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
MVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV
CEECCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
SGASGSRFNRR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]