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The map label for this gene is kdgR [H]

Identifier: 119855218

GI number: 119855218

Start: 41274

End: 42023

Strand: Reverse

Name: kdgR [H]

Synonym: Mkms_5832

Alternate gene names: 119855218

Gene position: 42023-41274 (Counterclockwise)

Preceding gene: 119855222

Following gene: 119855217

Centisome position: 19.39

GC content: 63.73

Gene sequence:

>750_bases
ATGTCACGGGATGGGTTGTTGTCGCAGCTGGAGAAGTCCGCGCTGGTGCTCGACGCATTCCCTGGCGGATCCGCGCTGAC
ATTGGCCCAAGTGTGCACCAGGACCGGACTTGCTCGCTCGACAGTCCACCGCCTCCTCGTTGACCTGGCCACGCTTGGAT
GGATCGGCCGCTCCGGCAACACCTTCGAACTCGGAATCGGCCTGTTCGAACTCGGCGAACGCGTCGCCGTGAAGCACCGT
CTGCGCACGGCGGCGATGCCGTTCATGCAAGACCTGTACGCCGTGACCGGCCAAACGGTGCACCTGGCCGTGCGCAATCG
ATTCGATGCGGTGTATATCGAGAAGCTGTCCGGCCACATTCCGCTACCGCTGCCCTCACAGATCGGCGGACGGCTCCCCC
TTACCTGCACTGCGGTGGGCAAGGCGTTACTCGCATCCGAGACCGCGGAGTTGCGCATCGAGGTCCTCGCCCAACCCTTG
CGTCGTTACACCGTGAACTCCATCACCGACCCCAAGAAACTTGCCCGCGAACTCGACGACATTTGCCGTACCGGAGTTGC
GGTCGAACGCGAGGAATCTGCACTCGGCGGATGCTGTGTCGCCGTCCCAGTTCTGCTGGACGGCCAGCCAATCGCGGCCC
TATCGGTGTCCGTTCCGACCGAACAGTTCAGACCTGAACTCCTCGCCCCAGCCGTGCGCACGGGAGCATTGGCCTTAGGG
CGCGTTCTCGCCAGAGCCGCAGCACCATGA

Upstream 100 bases:

>100_bases
TGAGCGAGCCGATCGGCCGCTTCGCTGATCGCCTGGGAACACACCGATGTCATGACAACCACGCTATGGACGCCTCGCGA
CCGTGGCTAGGATAAATCCC

Downstream 100 bases:

>100_bases
CCCCCTGGACAACGCATTGGCCGAGACCACCGTCGGATCGTTCAGAACGAAATCGTCCGCCGACAGGGCCCGTGGCGTGA
ACCAGGCCGAGCTGGCGACC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSRDGLLSQLEKSALVLDAFPGGSALTLAQVCTRTGLARSTVHRLLVDLATLGWIGRSGNTFELGIGLFELGERVAVKHR
LRTAAMPFMQDLYAVTGQTVHLAVRNRFDAVYIEKLSGHIPLPLPSQIGGRLPLTCTAVGKALLASETAELRIEVLAQPL
RRYTVNSITDPKKLARELDDICRTGVAVEREESALGGCCVAVPVLLDGQPIAALSVSVPTEQFRPELLAPAVRTGALALG
RVLARAAAP

Sequences:

>Translated_249_residues
MSRDGLLSQLEKSALVLDAFPGGSALTLAQVCTRTGLARSTVHRLLVDLATLGWIGRSGNTFELGIGLFELGERVAVKHR
LRTAAMPFMQDLYAVTGQTVHLAVRNRFDAVYIEKLSGHIPLPLPSQIGGRLPLTCTAVGKALLASETAELRIEVLAQPL
RRYTVNSITDPKKLARELDDICRTGVAVEREESALGGCCVAVPVLLDGQPIAALSVSVPTEQFRPELLAPAVRTGALALG
RVLARAAAP
>Mature_248_residues
SRDGLLSQLEKSALVLDAFPGGSALTLAQVCTRTGLARSTVHRLLVDLATLGWIGRSGNTFELGIGLFELGERVAVKHRL
RTAAMPFMQDLYAVTGQTVHLAVRNRFDAVYIEKLSGHIPLPLPSQIGGRLPLTCTAVGKALLASETAELRIEVLAQPLR
RYTVNSITDPKKLARELDDICRTGVAVEREESALGGCCVAVPVLLDGQPIAALSVSVPTEQFRPELLAPAVRTGALALGR
VLARAAAP

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=221, Percent_Identity=33.4841628959276, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=32.1138211382114, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789999, Length=216, Percent_Identity=29.6296296296296, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=29.2490118577075, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI87082359, Length=201, Percent_Identity=28.8557213930348, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790752, Length=170, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788581, Length=211, Percent_Identity=28.436018957346, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26519; Mature: 26388

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDGLLSQLEKSALVLDAFPGGSALTLAQVCTRTGLARSTVHRLLVDLATLGWIGRSGN
CCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
TFELGIGLFELGERVAVKHRLRTAAMPFMQDLYAVTGQTVHLAVRNRFDAVYIEKLSGHI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCC
PLPLPSQIGGRLPLTCTAVGKALLASETAELRIEVLAQPLRRYTVNSITDPKKLARELDD
CCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ICRTGVAVEREESALGGCCVAVPVLLDGQPIAALSVSVPTEQFRPELLAPAVRTGALALG
HHHCCCCEECCHHHHCCHHHHHHHHCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
RVLARAAAP
HHHHHHCCC
>Mature Secondary Structure 
SRDGLLSQLEKSALVLDAFPGGSALTLAQVCTRTGLARSTVHRLLVDLATLGWIGRSGN
CCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
TFELGIGLFELGERVAVKHRLRTAAMPFMQDLYAVTGQTVHLAVRNRFDAVYIEKLSGHI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCC
PLPLPSQIGGRLPLTCTAVGKALLASETAELRIEVLAQPLRRYTVNSITDPKKLARELDD
CCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ICRTGVAVEREESALGGCCVAVPVLLDGQPIAALSVSVPTEQFRPELLAPAVRTGALALG
HHHCCCCEECCHHHHCCHHHHHHHHCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
RVLARAAAP
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]