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The map label for this gene is nhaA [H]

Identifier: 119854999

GI number: 119854999

Start: 117034

End: 117699

Strand: Direct

Name: nhaA [H]

Synonym: Mkms_5606

Alternate gene names: 119854999

Gene position: 117034-117699 (Clockwise)

Preceding gene: 119854997

Following gene: 119855000

Centisome position: 38.74

GC content: 60.51

Gene sequence:

>666_bases
GTGAATCCACTGACTCGAATTCTGCTGACTTTCTTCATAGTCATCACTGTCGCCATCGGTGCCGGTGTGTACTTCTCGAC
CCGAGATGGCGGAACCGCAGGATCAGGTGGAACACAGGCTGATGGCGAAGCCCAGGTAGTCCGCGAGAACAGTCATCGCC
TCAGTTCCGCGCCCGACAGCGATGTGACCTTTGTCGAGTTTCTCGATTTCGAGTGCGAAGGGTGCCGCGCGGCGTTCCCC
GCCGTTGAGCAGCTGCGCGCCCAGTACGGCCAGCAAGTCACCTTCGTCGCCCGGTACTTTCCGATGCCTGGCCACTTCAA
CGGAGAACGCGCGGCGCGCGCGGTAGAAGCGGCAGCGCAGCAAGGCCAGTTCGAACCCATGTACAAGAAGATGTTCGAGA
CGCAGAGTCAGTGGGGCGAAAAGCAGGTACCCGCAGACGAGGTATTCCGCGGATTTGCAACGGAATTAGGTCTCGACGTG
GCCGCGTGGGAGGAGGCGTACAACGCTCCAGCCACCCTCGATCGAATCGAAGAGGACGTCGCCGACGGCACCGCCCTCGG
CGTGCAGGGCACGCCCACATTCTTCGTCAACGGAAAGCAAATAGAGATCAAGACCTACGCAGACCTGGGCGCTGCGATCA
AGAACGCTCTCGGTGAGCAGCAGTAG

Upstream 100 bases:

>100_bases
TTGAACGTGGGGGAGAGCTATCGTGGTAGAAATATTTACGTAGATACACCGTAGATTGCTCAGGCTCACAGAGCGCTACG
GAGCGAAAGGAACTGCCGGC

Downstream 100 bases:

>100_bases
TCAGCGCCTGGCGGGCCCCAACCCGCTTCGGCGTGGCGAACCGAGACCGTAACGGGCTATGCCGTCCTGACCACCCGGCA
CAACGCTCGCGGACAGCGAA

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNPLTRILLTFFIVITVAIGAGVYFSTRDGGTAGSGGTQADGEAQVVRENSHRLSSAPDSDVTFVEFLDFECEGCRAAFP
AVEQLRAQYGQQVTFVARYFPMPGHFNGERAARAVEAAAQQGQFEPMYKKMFETQSQWGEKQVPADEVFRGFATELGLDV
AAWEEAYNAPATLDRIEEDVADGTALGVQGTPTFFVNGKQIEIKTYADLGAAIKNALGEQQ

Sequences:

>Translated_221_residues
MNPLTRILLTFFIVITVAIGAGVYFSTRDGGTAGSGGTQADGEAQVVRENSHRLSSAPDSDVTFVEFLDFECEGCRAAFP
AVEQLRAQYGQQVTFVARYFPMPGHFNGERAARAVEAAAQQGQFEPMYKKMFETQSQWGEKQVPADEVFRGFATELGLDV
AAWEEAYNAPATLDRIEEDVADGTALGVQGTPTFFVNGKQIEIKTYADLGAAIKNALGEQQ
>Mature_221_residues
MNPLTRILLTFFIVITVAIGAGVYFSTRDGGTAGSGGTQADGEAQVVRENSHRLSSAPDSDVTFVEFLDFECEGCRAAFP
AVEQLRAQYGQQVTFVARYFPMPGHFNGERAARAVEAAAQQGQFEPMYKKMFETQSQWGEKQVPADEVFRGFATELGLDV
AAWEEAYNAPATLDRIEEDVADGTALGVQGTPTFFVNGKQIEIKTYADLGAAIKNALGEQQ

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 24007; Mature: 24007

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLTRILLTFFIVITVAIGAGVYFSTRDGGTAGSGGTQADGEAQVVRENSHRLSSAPDS
CCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHCCCHHCCCCCCC
DVTFVEFLDFECEGCRAAFPAVEQLRAQYGQQVTFVARYFPMPGHFNGERAARAVEAAAQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHH
QGQFEPMYKKMFETQSQWGEKQVPADEVFRGFATELGLDVAAWEEAYNAPATLDRIEEDV
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
ADGTALGVQGTPTFFVNGKQIEIKTYADLGAAIKNALGEQQ
CCCCEECCCCCCEEEECCCEEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNPLTRILLTFFIVITVAIGAGVYFSTRDGGTAGSGGTQADGEAQVVRENSHRLSSAPDS
CCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHCCCHHCCCCCCC
DVTFVEFLDFECEGCRAAFPAVEQLRAQYGQQVTFVARYFPMPGHFNGERAARAVEAAAQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHH
QGQFEPMYKKMFETQSQWGEKQVPADEVFRGFATELGLDVAAWEEAYNAPATLDRIEEDV
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
ADGTALGVQGTPTFFVNGKQIEIKTYADLGAAIKNALGEQQ
CCCCEECCCCCCEEEECCCEEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA