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The map label for this gene is mmpL3 [H]

Identifier: 119854941

GI number: 119854941

Start: 55964

End: 56695

Strand: Direct

Name: mmpL3 [H]

Synonym: Mkms_5546

Alternate gene names: 119854941

Gene position: 55964-56695 (Clockwise)

Preceding gene: 119854939

Following gene: 119854942

Centisome position: 18.53

GC content: 60.52

Gene sequence:

>732_bases
GTGCTTCCGATCAAAGCCGCCATCATGAGCGTATTGACCCTCGGTGCCACCATGGGTGTGCTCACCGCGATGTTCGTTGA
CGGCCTCTTCTCGAGTTGGCTCAACTTCACTCCCCAACCGCTGAGCGCTCCTGTACTCGGATTGGTCATCGCCATCATCT
ATGGCCTGTGCACCGACTACGAAGTGTTTCTAGTGTCCCGCATGATCGAAGCGCGGGCACAAGGTATGTCCACCGCCGAG
TCCATTCGCATTGGCACCGCCACCACAGGGCGCCTCATCACCGCCGCCGCACTCATCCTCGTCGTCGTCGCCGGGGCATT
CGTCTTCTCCGAGTTGGTCATGCTCAAATACCTCGCATTCGGCCTACTTACAGCCCTGCTCCTAGACGCCACCGTCATTC
GGATGTTCCTCGTTCCCGCCCTTATGAAATGGCTTGGCGACGAATGCTGGTGGGCACCCCAATGGATGAAACGTATCCAA
CAGCGCATCGGACTCGGCGAAGTGCACTTGCCCGATGAACCACGTCGACCGGCGAACCGCAGCGTGATCCCCTCCCATCT
CAGCGTCCGAGACAACCCGGGGCTACACCGCCCGAGCGTCCCGCCTGACAGAAGACCCAGGCATTCCGCCGAACATCGAC
AACGAACACCAGATCAAACACCGCCCAACGGCCGGTCCCCGATTTTCCACCCCGACGAAGCCGCCACCACACCGCTATCT
GTGCGGCCATAG

Upstream 100 bases:

>100_bases
GGAATTCTTGATAGGTCCGCGGATAGTCCACACCACCCACAGGAGCGCCCTCGAAACCCATGCTGACCAGCTTAGGTCCA
CTTAAGCGGATAAGCAGTTC

Downstream 100 bases:

>100_bases
GCGATGGGACCGAGCCGAAACATGACGACCGAGAACTGATGGTGCAAGCCTTCGCAGGACTTCCGGGCGTCGCGACCCCT
TGCAAGACGCTTGTTCGACG

Product: RND superfamily drug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLPIKAAIMSVLTLGATMGVLTAMFVDGLFSSWLNFTPQPLSAPVLGLVIAIIYGLCTDYEVFLVSRMIEARAQGMSTAE
SIRIGTATTGRLITAAALILVVVAGAFVFSELVMLKYLAFGLLTALLLDATVIRMFLVPALMKWLGDECWWAPQWMKRIQ
QRIGLGEVHLPDEPRRPANRSVIPSHLSVRDNPGLHRPSVPPDRRPRHSAEHRQRTPDQTPPNGRSPIFHPDEAATTPLS
VRP

Sequences:

>Translated_243_residues
MLPIKAAIMSVLTLGATMGVLTAMFVDGLFSSWLNFTPQPLSAPVLGLVIAIIYGLCTDYEVFLVSRMIEARAQGMSTAE
SIRIGTATTGRLITAAALILVVVAGAFVFSELVMLKYLAFGLLTALLLDATVIRMFLVPALMKWLGDECWWAPQWMKRIQ
QRIGLGEVHLPDEPRRPANRSVIPSHLSVRDNPGLHRPSVPPDRRPRHSAEHRQRTPDQTPPNGRSPIFHPDEAATTPLS
VRP
>Mature_243_residues
MLPIKAAIMSVLTLGATMGVLTAMFVDGLFSSWLNFTPQPLSAPVLGLVIAIIYGLCTDYEVFLVSRMIEARAQGMSTAE
SIRIGTATTGRLITAAALILVVVAGAFVFSELVMLKYLAFGLLTALLLDATVIRMFLVPALMKWLGDECWWAPQWMKRIQ
QRIGLGEVHLPDEPRRPANRSVIPSHLSVRDNPGLHRPSVPPDRRPRHSAEHRQRTPDQTPPNGRSPIFHPDEAATTPLS
VRP

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 26734; Mature: 26734

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]