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The map label for this gene is eccA2 [H]

Identifier: 119854898

GI number: 119854898

Start: 8316

End: 10097

Strand: Direct

Name: eccA2 [H]

Synonym: Mkms_5503

Alternate gene names: 119854898

Gene position: 8316-10097 (Clockwise)

Preceding gene: 119854897

Following gene: 119854899

Centisome position: 2.75

GC content: 66.84

Gene sequence:

>1782_bases
ATGACCTCGCCGACCGAACAGCGCCGCGCGTTCGACGCCGCGATGGACAGCTACCGCTCCGGGGACCGCGCCACCGCACT
GGGCATCTTTACCCGCGTCACCGCCGACAACCCCGCCATGTCGGACGCCTGGCTGGGTCGCCTGGCGTGCGGAGACCAGG
AACTCGACACCCTGGCCGGCGCGCACGAGAACTCCCGGGCGCTCTACCGCGAAACCCGCCGCATCGGTCTCAAGGCCGGC
GAGCTTCACGCCGTGATCGTGGCACCGCTATACCTGACGCTTCCGGTGTGGTCACGGGCCACGTTGGCTCTGGCCTACGC
CTCAGCACTCATCCGCGCCGAACAGTACGCCCAAGCCGCGTCACTGCTCGACCACCCGGTCATCACCGAGGACACCCAAG
CCGCCCAATGGCGTCAATTCATCACCGCCACACTGCACTACCGCACCCGGCGTTGGCCGGATCTGCTCGGCGCCACGGCG
GTGTCCCCGCCGCCGGAGGCAACCTATGTCCTGGAACCTGTCAGCGCCGCGGTCGCGGCGCTGACCGCGGCGGCCTCCGC
CAGCTTGGGACAGTTCCAAACCGCACTCGACACCGCTGACAAGATCCACACCGACAACCCCTACGTCAGCGCCGATGTGG
CGCTCACCCGCGGCTGGTGCCTGCGTGAACTTGGCGACCCCGACGCTGCGCTGGCGGCGTTCCGCGCCGCCGCAGTGGAG
GGGCAGTTGTTGCCCGCGGCCCAGCAGGCCATCGACGACCCCAGCTACCGCCTTGTGGTCACCGATCCCGAAACCATCGC
CACCCGCACCGACAAGTGGGACCCGGCCACCGAGACCAGCCGCGCCCAGCGCGACGCGGCCGCATTGGCCGAAGAGCAGA
AGGAAGTACTGGCCAACGCCAAGCGCCGCCTCGACGAACTGATTGGACTGGAGGGCCCCAAAGAGCAGATCGCGGTGTGG
CGCACCGAAATTCAGATTGATCAGCTGATGGCCGCTCAGGGCGATGAAACGTCGTCGACCGGTGAGAACCACATGGTCTT
GGAAGGTCCGCCCGGGACGGCGAAAACCACGTTCGCCCGCATTGTTGCCGAGATCCTGTTCGGCTTGGGCAAGATTCAGC
GCCCCGAGGTCATGGAAGTTACCGAGGAGGACCTTGTCGTCGGTTACGTCTCTCAGACCGCGCAGCGGATGAAAGAGGTC
TGCGAAGAGGCGTTGGGCGGGGTGTTGTTCATCGACGAGGCCTACCGGCTGGTGCCGGAGACTGAGGGCCACAGCTTCGG
CAAGGACGCCATCAACACGCTGCTGAAATACATGGAGGACTTCCGCGACCGGCTGGTCGTCATCGTCGCTGGCTATCCCA
AAGAGATGCGCCGCTTCCTGGCCGCCAATCCGGGCCTGGCGTCTCGGTTTAACTTCACCCTGACCTTCACCAGCTACACC
GCCGATGAAATCGTGGCGATCGGGCGCCACATCGCGGGTAAGGAGAAGATCGCAATTGCCGAGGAGGCGTGGCCCATGCT
GCACGCCGAGGCCACCCGCTTGCGCGCCACACCGACCGACGCCGGCACCGCGCTCGATATCGCCGGCAACGGCCGCTACG
CCCGCAAGGTGGTCGTTGCCTGCAAACGGGAGCGCGCCCGGCGACTCAGCAGTAACACTCCGGAGGAATTGGCCGCCTTG
GCCGCCGCTGATCCGTCGCTGCTGGTGGTCAACACCGATGACATGGCCCGCGCCCTGGCCTCCTCGCAGAGCGGCGATAT
CAGCGCCGCGCCGGCGACATGA

Upstream 100 bases:

>100_bases
GTTTCCACCACCCGACGACGAGTCAGGACCTTCCTCCGGACCACCGACTACCGTCAATCCCATCACCAACACGTAGCCAA
GCAGGGGAGAAGCGCCACCC

Downstream 100 bases:

>100_bases
CTGCCCATACTGGCCCGGCGCAGGCATCGAAGCCTCATATTGCCGCGTCTTTCTTCTCCGAGCAGCTGGCCGCGCTTATC
GAGGACAATCCTCGGGTTCG

Product: ATPase central domain-containing protein

Products: NA

Alternate protein names: ESX conserved component A2; Type VII secretion system protein EccA2; T7SS protein EccA2 [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MTSPTEQRRAFDAAMDSYRSGDRATALGIFTRVTADNPAMSDAWLGRLACGDQELDTLAGAHENSRALYRETRRIGLKAG
ELHAVIVAPLYLTLPVWSRATLALAYASALIRAEQYAQAASLLDHPVITEDTQAAQWRQFITATLHYRTRRWPDLLGATA
VSPPPEATYVLEPVSAAVAALTAAASASLGQFQTALDTADKIHTDNPYVSADVALTRGWCLRELGDPDAALAAFRAAAVE
GQLLPAAQQAIDDPSYRLVVTDPETIATRTDKWDPATETSRAQRDAAALAEEQKEVLANAKRRLDELIGLEGPKEQIAVW
RTEIQIDQLMAAQGDETSSTGENHMVLEGPPGTAKTTFARIVAEILFGLGKIQRPEVMEVTEEDLVVGYVSQTAQRMKEV
CEEALGGVLFIDEAYRLVPETEGHSFGKDAINTLLKYMEDFRDRLVVIVAGYPKEMRRFLAANPGLASRFNFTLTFTSYT
ADEIVAIGRHIAGKEKIAIAEEAWPMLHAEATRLRATPTDAGTALDIAGNGRYARKVVVACKRERARRLSSNTPEELAAL
AAADPSLLVVNTDDMARALASSQSGDISAAPAT

Sequences:

>Translated_593_residues
MTSPTEQRRAFDAAMDSYRSGDRATALGIFTRVTADNPAMSDAWLGRLACGDQELDTLAGAHENSRALYRETRRIGLKAG
ELHAVIVAPLYLTLPVWSRATLALAYASALIRAEQYAQAASLLDHPVITEDTQAAQWRQFITATLHYRTRRWPDLLGATA
VSPPPEATYVLEPVSAAVAALTAAASASLGQFQTALDTADKIHTDNPYVSADVALTRGWCLRELGDPDAALAAFRAAAVE
GQLLPAAQQAIDDPSYRLVVTDPETIATRTDKWDPATETSRAQRDAAALAEEQKEVLANAKRRLDELIGLEGPKEQIAVW
RTEIQIDQLMAAQGDETSSTGENHMVLEGPPGTAKTTFARIVAEILFGLGKIQRPEVMEVTEEDLVVGYVSQTAQRMKEV
CEEALGGVLFIDEAYRLVPETEGHSFGKDAINTLLKYMEDFRDRLVVIVAGYPKEMRRFLAANPGLASRFNFTLTFTSYT
ADEIVAIGRHIAGKEKIAIAEEAWPMLHAEATRLRATPTDAGTALDIAGNGRYARKVVVACKRERARRLSSNTPEELAAL
AAADPSLLVVNTDDMARALASSQSGDISAAPAT
>Mature_592_residues
TSPTEQRRAFDAAMDSYRSGDRATALGIFTRVTADNPAMSDAWLGRLACGDQELDTLAGAHENSRALYRETRRIGLKAGE
LHAVIVAPLYLTLPVWSRATLALAYASALIRAEQYAQAASLLDHPVITEDTQAAQWRQFITATLHYRTRRWPDLLGATAV
SPPPEATYVLEPVSAAVAALTAAASASLGQFQTALDTADKIHTDNPYVSADVALTRGWCLRELGDPDAALAAFRAAAVEG
QLLPAAQQAIDDPSYRLVVTDPETIATRTDKWDPATETSRAQRDAAALAEEQKEVLANAKRRLDELIGLEGPKEQIAVWR
TEIQIDQLMAAQGDETSSTGENHMVLEGPPGTAKTTFARIVAEILFGLGKIQRPEVMEVTEEDLVVGYVSQTAQRMKEVC
EEALGGVLFIDEAYRLVPETEGHSFGKDAINTLLKYMEDFRDRLVVIVAGYPKEMRRFLAANPGLASRFNFTLTFTSYTA
DEIVAIGRHIAGKEKIAIAEEAWPMLHAEATRLRATPTDAGTALDIAGNGRYARKVVVACKRERARRLSSNTPEELAALA
AADPSLLVVNTDDMARALASSQSGDISAAPAT

Specific function: Shows ATPase activity. Could provide energy for export of ESX-2 substrates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: NA

Molecular weight: Translated: 64246; Mature: 64115

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTEQRRAFDAAMDSYRSGDRATALGIFTRVTADNPAMSDAWLGRLACGDQELDTLAG
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHC
AHENSRALYRETRRIGLKAGELHAVIVAPLYLTLPVWSRATLALAYASALIRAEQYAQAA
CCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SLLDHPVITEDTQAAQWRQFITATLHYRTRRWPDLLGATAVSPPPEATYVLEPVSAAVAA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEECHHHHHHHH
LTAAASASLGQFQTALDTADKIHTDNPYVSADVALTRGWCLRELGDPDAALAAFRAAAVE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCHHHHHCCCCHHHHHHHHHHHHC
GQLLPAAQQAIDDPSYRLVVTDPETIATRTDKWDPATETSRAQRDAAALAEEQKEVLANA
CCCCHHHHHHCCCCCEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KRRLDELIGLEGPKEQIAVWRTEIQIDQLMAAQGDETSSTGENHMVLEGPPGTAKTTFAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHH
IVAEILFGLGKIQRPEVMEVTEEDLVVGYVSQTAQRMKEVCEEALGGVLFIDEAYRLVPE
HHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCC
TEGHSFGKDAINTLLKYMEDFRDRLVVIVAGYPKEMRRFLAANPGLASRFNFTLTFTSYT
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEEEEECCC
ADEIVAIGRHIAGKEKIAIAEEAWPMLHAEATRLRATPTDAGTALDIAGNGRYARKVVVA
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCHHHHHHHHH
CKRERARRLSSNTPEELAALAAADPSLLVVNTDDMARALASSQSGDISAAPAT
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TSPTEQRRAFDAAMDSYRSGDRATALGIFTRVTADNPAMSDAWLGRLACGDQELDTLAG
CCCHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHC
AHENSRALYRETRRIGLKAGELHAVIVAPLYLTLPVWSRATLALAYASALIRAEQYAQAA
CCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SLLDHPVITEDTQAAQWRQFITATLHYRTRRWPDLLGATAVSPPPEATYVLEPVSAAVAA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEECHHHHHHHH
LTAAASASLGQFQTALDTADKIHTDNPYVSADVALTRGWCLRELGDPDAALAAFRAAAVE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCHHHHHCCCCHHHHHHHHHHHHC
GQLLPAAQQAIDDPSYRLVVTDPETIATRTDKWDPATETSRAQRDAAALAEEQKEVLANA
CCCCHHHHHHCCCCCEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KRRLDELIGLEGPKEQIAVWRTEIQIDQLMAAQGDETSSTGENHMVLEGPPGTAKTTFAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHH
IVAEILFGLGKIQRPEVMEVTEEDLVVGYVSQTAQRMKEVCEEALGGVLFIDEAYRLVPE
HHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCC
TEGHSFGKDAINTLLKYMEDFRDRLVVIVAGYPKEMRRFLAANPGLASRFNFTLTFTSYT
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEEEEECCC
ADEIVAIGRHIAGKEKIAIAEEAWPMLHAEATRLRATPTDAGTALDIAGNGRYARKVVVA
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCHHHHHHHHH
CKRERARRLSSNTPEELAALAAADPSLLVVNTDDMARALASSQSGDISAAPAT
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]