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The map label for this gene is cat2 [H]

Identifier: 119776030

GI number: 119776030

Start: 3445442

End: 3446728

Strand: Reverse

Name: cat2 [H]

Synonym: Sama_2898

Alternate gene names: 119776030

Gene position: 3446728-3445442 (Counterclockwise)

Preceding gene: 119776032

Following gene: 119776028

Centisome position: 80.04

GC content: 57.34

Gene sequence:

>1287_bases
ATGGTACCCAAGTACTGTGCCACCGCTCTGGAGGCGGTGTCGTTAATCGATAATGACGAATTCATCTGGACCCACTCCAT
GGGGGCGACGCCTAGACTCTTGCTGGAGGCCCTGGCTGAACATGCGCTAAACCGCACTAATCTCACGCTATTACAATTAC
ATACTGAGCATGCCGAATGCCTCAGTGGCCCAGAGCTTGAGGGGCATTTGCGCCATCGCTGCTATTTTGGTGGCAAGCCG
ACCCGTGAACTGCTCGCCAGTGCCCGTGCCGACTATGTGCCGGTGTTTTTATCCGAAGTACCAAAGCTTTTTCGCCGCCG
TGAGCAGCGTATCGACACTGCAATAGTGCAGGTGTCACCGCCGGATAAGCATGGCATGTGTTCTCTTGGTATTTCAGTGG
AGGCGACCCGCGCCGCCTGTGAGGTGGCTGGTAAGATAATTGCCCATATCAACCCCCGTATGCCCCGTACCCACGGCGAC
AGTTTTCTTCCGCTGACCCGTTTTGATGCCGTGTTTGAAGCGCCCATGGAGCTACCGGAACATGCTCTGGCGACGACAGA
TGCGGTAAGCCAGGCCATTGGCCGTAATGTGGCGGCGCTGGTACGCGACGGTGACTGCTTACAGATGGGGATTGGTGGTA
TTCCCGATGCCGTGCTGGGTTGTCTTGGCAATCACCAGCACCTGGGGGTGCATACGGAGCTGTTTTCTGACGGCATCTTG
AGTTTGGTGGAGCGCGGCGTGGTGGATAACAGCCGCAAACGCTTCGCCACCGGCAAGCTGGTAACGGGTTTTGCTTTGGG
TAGCCGCAGGCTTTACGACTTTGTGGACGACAATCCCCAGGTGGCATTTTTGGATATTGAGCAGGTCAACGACACCGCCA
TCATCCGCCGTAACCCGCAGGTGATGGCCATTAACTCGGCACTGCAGGTGGATGTGACCGGTCAGGTGTGCGCCGACTCC
ATAGGGACCCGTATTTATTCCGGTGTGGGCGGCCAAATGGACTTTATCCGCGGCGCCGGACTCTCTGAAGGGGGCCGCTC
TGTGATTGCCATGCCGAGTACGGCAGCCGGAGGCAAGGTGTCCCGCATCAGTACAGTGTTGTCTCCCGGTGCCGGGGTGG
TGACCACCCGCGCCCATGTGCACTACATAGTGACCGAATTCGGTGTGGCCTACATGCGCGGTAAATCCATTCGTGAGCGG
GCCCGTTCTTTGATTGATATTGCCCACCCGGATTTTCGTGAAGCCCTGGCCCGTGAAACCCATGAAATGTGGGGATTGTT
GCTGTGA

Upstream 100 bases:

>100_bases
TGGATTTCGGCCCATTAGCCGGCCAAAACATGATCTGTGTCGGGATGAAGGTTGAAATTAGCTGCTATAACAGCAATGTC
TGATTCATCAAGGAAGCCCG

Downstream 100 bases:

>100_bases
CGAAAGCCCGTCAATCTAAGGTGAGGCGTTAAAGAGCAAGCCCTGTGATACCCGCAAGTAAAAACACCTCGTTTATGGCG
AGGTGTTTTTGTTGGCAGGG

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MVPKYCATALEAVSLIDNDEFIWTHSMGATPRLLLEALAEHALNRTNLTLLQLHTEHAECLSGPELEGHLRHRCYFGGKP
TRELLASARADYVPVFLSEVPKLFRRREQRIDTAIVQVSPPDKHGMCSLGISVEATRAACEVAGKIIAHINPRMPRTHGD
SFLPLTRFDAVFEAPMELPEHALATTDAVSQAIGRNVAALVRDGDCLQMGIGGIPDAVLGCLGNHQHLGVHTELFSDGIL
SLVERGVVDNSRKRFATGKLVTGFALGSRRLYDFVDDNPQVAFLDIEQVNDTAIIRRNPQVMAINSALQVDVTGQVCADS
IGTRIYSGVGGQMDFIRGAGLSEGGRSVIAMPSTAAGGKVSRISTVLSPGAGVVTTRAHVHYIVTEFGVAYMRGKSIRER
ARSLIDIAHPDFREALARETHEMWGLLL

Sequences:

>Translated_428_residues
MVPKYCATALEAVSLIDNDEFIWTHSMGATPRLLLEALAEHALNRTNLTLLQLHTEHAECLSGPELEGHLRHRCYFGGKP
TRELLASARADYVPVFLSEVPKLFRRREQRIDTAIVQVSPPDKHGMCSLGISVEATRAACEVAGKIIAHINPRMPRTHGD
SFLPLTRFDAVFEAPMELPEHALATTDAVSQAIGRNVAALVRDGDCLQMGIGGIPDAVLGCLGNHQHLGVHTELFSDGIL
SLVERGVVDNSRKRFATGKLVTGFALGSRRLYDFVDDNPQVAFLDIEQVNDTAIIRRNPQVMAINSALQVDVTGQVCADS
IGTRIYSGVGGQMDFIRGAGLSEGGRSVIAMPSTAAGGKVSRISTVLSPGAGVVTTRAHVHYIVTEFGVAYMRGKSIRER
ARSLIDIAHPDFREALARETHEMWGLLL
>Mature_428_residues
MVPKYCATALEAVSLIDNDEFIWTHSMGATPRLLLEALAEHALNRTNLTLLQLHTEHAECLSGPELEGHLRHRCYFGGKP
TRELLASARADYVPVFLSEVPKLFRRREQRIDTAIVQVSPPDKHGMCSLGISVEATRAACEVAGKIIAHINPRMPRTHGD
SFLPLTRFDAVFEAPMELPEHALATTDAVSQAIGRNVAALVRDGDCLQMGIGGIPDAVLGCLGNHQHLGVHTELFSDGIL
SLVERGVVDNSRKRFATGKLVTGFALGSRRLYDFVDDNPQVAFLDIEQVNDTAIIRRNPQVMAINSALQVDVTGQVCADS
IGTRIYSGVGGQMDFIRGAGLSEGGRSVIAMPSTAAGGKVSRISTVLSPGAGVVTTRAHVHYIVTEFGVAYMRGKSIRER
ARSLIDIAHPDFREALARETHEMWGLLL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=217, Percent_Identity=31.7972350230415, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=423, Percent_Identity=44.2080378250591, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17538151, Length=440, Percent_Identity=39.5454545454545, Blast_Score=327, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6319456, Length=473, Percent_Identity=26.0042283298097, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21358615, Length=417, Percent_Identity=46.2829736211031, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46482; Mature: 46482

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPKYCATALEAVSLIDNDEFIWTHSMGATPRLLLEALAEHALNRTNLTLLQLHTEHAEC
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECHHHHH
LSGPELEGHLRHRCYFGGKPTRELLASARADYVPVFLSEVPKLFRRREQRIDTAIVQVSP
CCCCCCCCHHHHEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECC
PDKHGMCSLGISVEATRAACEVAGKIIAHINPRMPRTHGDSFLPLTRFDAVFEAPMELPE
CCCCCEEEECCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHH
HALATTDAVSQAIGRNVAALVRDGDCLQMGIGGIPDAVLGCLGNHQHLGVHTELFSDGIL
HHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHH
SLVERGVVDNSRKRFATGKLVTGFALGSRRLYDFVDDNPQVAFLDIEQVNDTAIIRRNPQ
HHHHHCCCCCCCHHHCCCCEEEEEECCCCHHHHHCCCCCCEEEEEEECCCCEEEEECCCC
VMAINSALQVDVTGQVCADSIGTRIYSGVGGQMDFIRGAGLSEGGRSVIAMPSTAAGGKV
EEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCH
SRISTVLSPGAGVVTTRAHVHYIVTEFGVAYMRGKSIRERARSLIDIAHPDFREALARET
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
HEMWGLLL
HHHHHCCC
>Mature Secondary Structure
MVPKYCATALEAVSLIDNDEFIWTHSMGATPRLLLEALAEHALNRTNLTLLQLHTEHAEC
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECHHHHH
LSGPELEGHLRHRCYFGGKPTRELLASARADYVPVFLSEVPKLFRRREQRIDTAIVQVSP
CCCCCCCCHHHHEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECC
PDKHGMCSLGISVEATRAACEVAGKIIAHINPRMPRTHGDSFLPLTRFDAVFEAPMELPE
CCCCCEEEECCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHH
HALATTDAVSQAIGRNVAALVRDGDCLQMGIGGIPDAVLGCLGNHQHLGVHTELFSDGIL
HHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHH
SLVERGVVDNSRKRFATGKLVTGFALGSRRLYDFVDDNPQVAFLDIEQVNDTAIIRRNPQ
HHHHHCCCCCCCHHHCCCCEEEEEECCCCHHHHHCCCCCCEEEEEEECCCCEEEEECCCC
VMAINSALQVDVTGQVCADSIGTRIYSGVGGQMDFIRGAGLSEGGRSVIAMPSTAAGGKV
EEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCH
SRISTVLSPGAGVVTTRAHVHYIVTEFGVAYMRGKSIRERARSLIDIAHPDFREALARET
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
HEMWGLLL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]