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The map label for this gene is pepV [H]

Identifier: 119774702

GI number: 119774702

Start: 1907877

End: 1909454

Strand: Direct

Name: pepV [H]

Synonym: Sama_1565

Alternate gene names: 119774702

Gene position: 1907877-1909454 (Clockwise)

Preceding gene: 119774698

Following gene: 119774707

Centisome position: 44.31

GC content: 57.6

Gene sequence:

>1578_bases
ATGCCGACAATGAACATGACAATGAAACCTGCCAATCCCTTTACTCTCAGCCGTCTGTCCGCCCTTATTCCCTTATTGCT
CACTATCCCCGGCTGGGCCGCAGCGCCTTCACCGGATGCCCAAAGAGTGGCCGCGTATGCGGCGTCGCATTTCCAGCAGG
CTCAAATCGATACCTTGAAAACCCTGGTCGGCTACGATACCCGTGCCCGTGACGGCCTGACGCCGGATACCGATCCTGTG
TTTGCCGATTTTAAGCGGGCACTCGGGGTAAAAGCCCGGATGCTGGGGCTTGATGTGGAGGACAACGGCTACGTGATGCT
GATAAGCCTGTCCCCGGAAGGCGCCGGGACAGATGTGAAAAAGGTTGGGGTGATCACCCACGGTGATGTGCAGCCTGCCG
ACCCCAGTCTGTGGCCCCAAAGCCCCTATGAATTGACCGAAACGGCCGATGGCAGGTTGGTAGGCCGCGGCGCGGAAGAT
GACAAAGGGCCTATCGCTACGGCGCTTTATGCCATGAAAGCCATCAAAGACAGCGGTATTGTGCTTAAGCGGCGCATCGA
GCTGCTGGTCTACATGGCTGAAGAGTCGGACTGGGAGCCCTTGAAGGACTTTTTGAAAACATATGAGCCTGCCGATATCA
ATATCACCCTGGATGCCGAGTATCCCGTGGTGACGGGGGAGAAGGGGTGGAGTCAAATCAAGCTCAGCCTGCCCCGCGTC
ATGGTGAAAGTGGGCGCAGATACGCCGGTGCTAACATATTTCTCTGGCGGCAGCTTTGCCAGCCAAATTCCCCAGCAGGC
CAGCGCCGTGATTCAAAACACCAATCCTGAACTGGTAGCCGCGCTCAAAGCCCGAGCCAAGACGTTGCCTATCAAGACTG
ACTTCATTGATGAGCCGCAAGGGCTCACAATCCATGCCACGGGCAAGGCGGCACATTCGTCCACACCGGAAGATGGCATC
AATGCCGTGGCTTACCTCGCCGAGCTTCTCTCACCCACCGCAGATGGCGGCATCCCCGAGTGGCCCATGACCACGGCAGC
GGTGACGGTGGATTTTTTACATTCGCTGGTGGGCACAGGGCTTTATGGAGAGCGCTTTGGCAAGCTTGGCTACAGCGATG
AGTTTATGGGGCCCATGACACTGGCACCTACTCTTATCACCGAGGGTAAAGAGGGGACAGACGTGACCCTTAATCTGCGC
CGTCCGGTGGGGCGCACCCCTGAAGCGCTGGATAAGCTGGCGATTGCAGCGATTCATGGCTGGCAGGATGCCAGGGGGAC
CCAGGTGGCTGATATAGAGACTTACTGGGGCACTCCCATGCTGATTGACGATGCTCCCCATCTGGAGACGCTGCTTGGGG
TGTTTGGCCATTACACCAACACAGCGGGCCCCAAACCCATCGCCATTGGTGGCTCGACCAATGCCAAACTCTTCCCCAAT
GCCTTAAGCTTTGGCCCAGCCATGCCCGGGATGGAGTACACGGGGCACAGCGAGTACGAATTTATCACCAGGGATCAGCT
TAAGCTGAACCTGGAAATGTACACAGCCGCGCTGGTGGAGTTGGCGATGCGCGAGTAA

Upstream 100 bases:

>100_bases
TAAATGGTTAATTCCTGTGCCTTGGGTGTGGCACACTGAGCCATCTACGCCGTTGGCGGGGCGAGCCGCGTGGCTCCTTT
TTTAAAACCAAAAACCATCA

Downstream 100 bases:

>100_bases
TACAGCCTGCCGGTTTTCAGGAAGTAAAAAAGCGCCTCAAAGGCGCTTTTTTATTAAAGGTGCGATTCAACGCGCTTCAG
TCCGCGTGTTTTAACGTACG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MPTMNMTMKPANPFTLSRLSALIPLLLTIPGWAAAPSPDAQRVAAYAASHFQQAQIDTLKTLVGYDTRARDGLTPDTDPV
FADFKRALGVKARMLGLDVEDNGYVMLISLSPEGAGTDVKKVGVITHGDVQPADPSLWPQSPYELTETADGRLVGRGAED
DKGPIATALYAMKAIKDSGIVLKRRIELLVYMAEESDWEPLKDFLKTYEPADINITLDAEYPVVTGEKGWSQIKLSLPRV
MVKVGADTPVLTYFSGGSFASQIPQQASAVIQNTNPELVAALKARAKTLPIKTDFIDEPQGLTIHATGKAAHSSTPEDGI
NAVAYLAELLSPTADGGIPEWPMTTAAVTVDFLHSLVGTGLYGERFGKLGYSDEFMGPMTLAPTLITEGKEGTDVTLNLR
RPVGRTPEALDKLAIAAIHGWQDARGTQVADIETYWGTPMLIDDAPHLETLLGVFGHYTNTAGPKPIAIGGSTNAKLFPN
ALSFGPAMPGMEYTGHSEYEFITRDQLKLNLEMYTAALVELAMRE

Sequences:

>Translated_525_residues
MPTMNMTMKPANPFTLSRLSALIPLLLTIPGWAAAPSPDAQRVAAYAASHFQQAQIDTLKTLVGYDTRARDGLTPDTDPV
FADFKRALGVKARMLGLDVEDNGYVMLISLSPEGAGTDVKKVGVITHGDVQPADPSLWPQSPYELTETADGRLVGRGAED
DKGPIATALYAMKAIKDSGIVLKRRIELLVYMAEESDWEPLKDFLKTYEPADINITLDAEYPVVTGEKGWSQIKLSLPRV
MVKVGADTPVLTYFSGGSFASQIPQQASAVIQNTNPELVAALKARAKTLPIKTDFIDEPQGLTIHATGKAAHSSTPEDGI
NAVAYLAELLSPTADGGIPEWPMTTAAVTVDFLHSLVGTGLYGERFGKLGYSDEFMGPMTLAPTLITEGKEGTDVTLNLR
RPVGRTPEALDKLAIAAIHGWQDARGTQVADIETYWGTPMLIDDAPHLETLLGVFGHYTNTAGPKPIAIGGSTNAKLFPN
ALSFGPAMPGMEYTGHSEYEFITRDQLKLNLEMYTAALVELAMRE
>Mature_524_residues
PTMNMTMKPANPFTLSRLSALIPLLLTIPGWAAAPSPDAQRVAAYAASHFQQAQIDTLKTLVGYDTRARDGLTPDTDPVF
ADFKRALGVKARMLGLDVEDNGYVMLISLSPEGAGTDVKKVGVITHGDVQPADPSLWPQSPYELTETADGRLVGRGAEDD
KGPIATALYAMKAIKDSGIVLKRRIELLVYMAEESDWEPLKDFLKTYEPADINITLDAEYPVVTGEKGWSQIKLSLPRVM
VKVGADTPVLTYFSGGSFASQIPQQASAVIQNTNPELVAALKARAKTLPIKTDFIDEPQGLTIHATGKAAHSSTPEDGIN
AVAYLAELLSPTADGGIPEWPMTTAAVTVDFLHSLVGTGLYGERFGKLGYSDEFMGPMTLAPTLITEGKEGTDVTLNLRR
PVGRTPEALDKLAIAAIHGWQDARGTQVADIETYWGTPMLIDDAPHLETLLGVFGHYTNTAGPKPIAIGGSTNAKLFPNA
LSFGPAMPGMEYTGHSEYEFITRDQLKLNLEMYTAALVELAMRE

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Drosophila melanogaster, GI24585880, Length=243, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 56560; Mature: 56429

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTMNMTMKPANPFTLSRLSALIPLLLTIPGWAAAPSPDAQRVAAYAASHFQQAQIDTLK
CCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLVGYDTRARDGLTPDTDPVFADFKRALGVKARMLGLDVEDNGYVMLISLSPEGAGTDVK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCEEEEEEECCCCCCCCCE
KVGVITHGDVQPADPSLWPQSPYELTETADGRLVGRGAEDDKGPIATALYAMKAIKDSGI
EEEEEEECCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCH
VLKRRIELLVYMAEESDWEPLKDFLKTYEPADINITLDAEYPVVTGEKGWSQIKLSLPRV
HHEEEEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHEEECCCEE
MVKVGADTPVLTYFSGGSFASQIPQQASAVIQNTNPELVAALKARAKTLPIKTDFIDEPQ
EEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GLTIHATGKAAHSSTPEDGINAVAYLAELLSPTADGGIPEWPMTTAAVTVDFLHSLVGTG
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LYGERFGKLGYSDEFMGPMTLAPTLITEGKEGTDVTLNLRRPVGRTPEALDKLAIAAIHG
CCHHHHCCCCCCCCCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
WQDARGTQVADIETYWGTPMLIDDAPHLETLLGVFGHYTNTAGPKPIAIGGSTNAKLFPN
CCCCCCCEEEEEHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCC
ALSFGPAMPGMEYTGHSEYEFITRDQLKLNLEMYTAALVELAMRE
HHHCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTMNMTMKPANPFTLSRLSALIPLLLTIPGWAAAPSPDAQRVAAYAASHFQQAQIDTLK
CCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLVGYDTRARDGLTPDTDPVFADFKRALGVKARMLGLDVEDNGYVMLISLSPEGAGTDVK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCEEEEEEECCCCCCCCCE
KVGVITHGDVQPADPSLWPQSPYELTETADGRLVGRGAEDDKGPIATALYAMKAIKDSGI
EEEEEEECCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCH
VLKRRIELLVYMAEESDWEPLKDFLKTYEPADINITLDAEYPVVTGEKGWSQIKLSLPRV
HHEEEEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHEEECCCEE
MVKVGADTPVLTYFSGGSFASQIPQQASAVIQNTNPELVAALKARAKTLPIKTDFIDEPQ
EEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GLTIHATGKAAHSSTPEDGINAVAYLAELLSPTADGGIPEWPMTTAAVTVDFLHSLVGTG
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LYGERFGKLGYSDEFMGPMTLAPTLITEGKEGTDVTLNLRRPVGRTPEALDKLAIAAIHG
CCHHHHCCCCCCCCCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
WQDARGTQVADIETYWGTPMLIDDAPHLETLLGVFGHYTNTAGPKPIAIGGSTNAKLFPN
CCCCCCCEEEEEHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCC
ALSFGPAMPGMEYTGHSEYEFITRDQLKLNLEMYTAALVELAMRE
HHHCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]