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The map label for this gene is macB [H]

Identifier: 119774609

GI number: 119774609

Start: 1780940

End: 1782193

Strand: Direct

Name: macB [H]

Synonym: Sama_1472

Alternate gene names: 119774609

Gene position: 1780940-1782193 (Clockwise)

Preceding gene: 119774608

Following gene: 119774611

Centisome position: 41.36

GC content: 54.94

Gene sequence:

>1254_bases
ATGATGCAGGATACTTTTAATCAATATCGGGCGGGCGTGGTACAAGCATTGGGTGAGATGCTGCACCACAAGTTACGCAC
GGCGCTGACACTGCTGGGGATGATTTTTGGGGTAGGAGCGGTGATTGCCATGCTCAGCGTGGGCGAAGGTGCCGAACGCG
AAGCTCTTAAGATGATTGAGTCCATGGGGATTAAAAATCTGGTGGTCAATGCGCGCCCATCGGAAGGAGAAGCCTTGAAA
ACTGTCCGCGAACACAGCATTGGCCTTAGCCTGCGTGACATCGAGAGTGCTATGGAAACCCTGCCTTTTATCGAGGCTTA
CAGCGCCGGTAAGCAGGTGAAGGTGTTTGGGCTTTTCAGTGTGCAGGGCCGCAGTGACGCGCTGGTGCAGGGCGTAACCC
CCAGCTATTTTGATTTGAGCGCCTTGAAACTTGCCGAAGGTCGACTTCTGGGCGACGAAGATGAACAGCACTTCAGGCAA
TTGGCGGTACTGGGGCCTGAAGCAGCCCGCAGCCTGTTCCCCCGGGGGGATGCTGTTGGTCAGCGCATCAAAATCAACCA
TCAGTGGTTTACCGTGGTTGGCGTGCTTGATGAAGGCGAAAAGGGCAAGTCGGCCATCGAAGGGGTTAAGGTGGGCGGCG
AGCGTAATCAGGTGTTTATTCCGCTGGCCACTGCGCTGAAAAAAATGCAGTTCAAGCCCCTCGAAGATGAACTCGATACC
ATCAAGTTTGCCCTGAAGGAGGGGATAGACCCGTCTCTGGCGGCAAAAAGCGTGGAACATCTGCTGTCACGTCGTCATGG
CAATGAGCAGGACTACGACATAGTGGTACCGGCCGATCTGCTTGCTCAGCACCAGCGGACCCAGCAAATTTTCAATATAG
TGATGGCCTGTGTGGCGGGAATTTCGCTGCTGGTGGGGGGCATAGGGATCATGAATATCATGCTGGCCACCATCTTGGAA
CGTACTTCCGAGATAGGTTTGCTGCGGGCGCTTGGTGCCACTCAAAAAGACATCGCCAGACAGTTTCTGATAGAAAGCAT
GGTGATTTCGGCCACCGGTGGCCTGATTGGTATTGGCGTGGGGTTATTGCTGGCGTTGGTTATTTCGGCGGCGGCCGGTT
GGCCCGTGGCATGGTCTGTGTTCGCCATTCTCCTGTCACTCTTGGTGTGTATGGCTGTGGGGATAGGTTTCGGCCTGTAT
CCAGCCAAAAAGGCCGCCAGGCTCGACCCTATTGTGGCACTTCAGCGTGACTGA

Upstream 100 bases:

>100_bases
TTACCCCCGGCAGTCGCAGCCTGAATCGAACCGTGATCCTTGAAGGCCTGAAAGAAGGGGATGTGGTCGCCCTGACAGTA
CCGCGCAGGAGAACACAGGC

Downstream 100 bases:

>100_bases
CGGGGACCTCGCGGGACAGGTGATACTTGCTCAATAGCCGGGCGAGGTCACCGGATCTCTCCAGCAGCCCAAACACAGCC
TGCAGATTATTTAAATCCAG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MMQDTFNQYRAGVVQALGEMLHHKLRTALTLLGMIFGVGAVIAMLSVGEGAEREALKMIESMGIKNLVVNARPSEGEALK
TVREHSIGLSLRDIESAMETLPFIEAYSAGKQVKVFGLFSVQGRSDALVQGVTPSYFDLSALKLAEGRLLGDEDEQHFRQ
LAVLGPEAARSLFPRGDAVGQRIKINHQWFTVVGVLDEGEKGKSAIEGVKVGGERNQVFIPLATALKKMQFKPLEDELDT
IKFALKEGIDPSLAAKSVEHLLSRRHGNEQDYDIVVPADLLAQHQRTQQIFNIVMACVAGISLLVGGIGIMNIMLATILE
RTSEIGLLRALGATQKDIARQFLIESMVISATGGLIGIGVGLLLALVISAAAGWPVAWSVFAILLSLLVCMAVGIGFGLY
PAKKAARLDPIVALQRD

Sequences:

>Translated_417_residues
MMQDTFNQYRAGVVQALGEMLHHKLRTALTLLGMIFGVGAVIAMLSVGEGAEREALKMIESMGIKNLVVNARPSEGEALK
TVREHSIGLSLRDIESAMETLPFIEAYSAGKQVKVFGLFSVQGRSDALVQGVTPSYFDLSALKLAEGRLLGDEDEQHFRQ
LAVLGPEAARSLFPRGDAVGQRIKINHQWFTVVGVLDEGEKGKSAIEGVKVGGERNQVFIPLATALKKMQFKPLEDELDT
IKFALKEGIDPSLAAKSVEHLLSRRHGNEQDYDIVVPADLLAQHQRTQQIFNIVMACVAGISLLVGGIGIMNIMLATILE
RTSEIGLLRALGATQKDIARQFLIESMVISATGGLIGIGVGLLLALVISAAAGWPVAWSVFAILLSLLVCMAVGIGFGLY
PAKKAARLDPIVALQRD
>Mature_417_residues
MMQDTFNQYRAGVVQALGEMLHHKLRTALTLLGMIFGVGAVIAMLSVGEGAEREALKMIESMGIKNLVVNARPSEGEALK
TVREHSIGLSLRDIESAMETLPFIEAYSAGKQVKVFGLFSVQGRSDALVQGVTPSYFDLSALKLAEGRLLGDEDEQHFRQ
LAVLGPEAARSLFPRGDAVGQRIKINHQWFTVVGVLDEGEKGKSAIEGVKVGGERNQVFIPLATALKKMQFKPLEDELDT
IKFALKEGIDPSLAAKSVEHLLSRRHGNEQDYDIVVPADLLAQHQRTQQIFNIVMACVAGISLLVGGIGIMNIMLATILE
RTSEIGLLRALGATQKDIARQFLIESMVISATGGLIGIGVGLLLALVISAAAGWPVAWSVFAILLSLLVCMAVGIGFGLY
PAKKAARLDPIVALQRD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=421, Percent_Identity=31.8289786223278, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44916; Mature: 44916

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQDTFNQYRAGVVQALGEMLHHKLRTALTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SMGIKNLVVNARPSEGEALKTVREHSIGLSLRDIESAMETLPFIEAYSAGKQVKVFGLFS
HCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
VQGRSDALVQGVTPSYFDLSALKLAEGRLLGDEDEQHFRQLAVLGPEAARSLFPRGDAVG
ECCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCC
QRIKINHQWFTVVGVLDEGEKGKSAIEGVKVGGERNQVFIPLATALKKMQFKPLEDELDT
CEEEECCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCHHHHHH
IKFALKEGIDPSLAAKSVEHLLSRRHGNEQDYDIVVPADLLAQHQRTQQIFNIVMACVAG
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ISLLVGGIGIMNIMLATILERTSEIGLLRALGATQKDIARQFLIESMVISATGGLIGIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
GLLLALVISAAAGWPVAWSVFAILLSLLVCMAVGIGFGLYPAKKAARLDPIVALQRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCC
>Mature Secondary Structure
MMQDTFNQYRAGVVQALGEMLHHKLRTALTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SMGIKNLVVNARPSEGEALKTVREHSIGLSLRDIESAMETLPFIEAYSAGKQVKVFGLFS
HCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
VQGRSDALVQGVTPSYFDLSALKLAEGRLLGDEDEQHFRQLAVLGPEAARSLFPRGDAVG
ECCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCC
QRIKINHQWFTVVGVLDEGEKGKSAIEGVKVGGERNQVFIPLATALKKMQFKPLEDELDT
CEEEECCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCHHHHHH
IKFALKEGIDPSLAAKSVEHLLSRRHGNEQDYDIVVPADLLAQHQRTQQIFNIVMACVAG
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ISLLVGGIGIMNIMLATILERTSEIGLLRALGATQKDIARQFLIESMVISATGGLIGIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
GLLLALVISAAAGWPVAWSVFAILLSLLVCMAVGIGFGLYPAKKAARLDPIVALQRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA