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The map label for this gene is ywrO [H]

Identifier: 119774528

GI number: 119774528

Start: 1682171

End: 1682764

Strand: Direct

Name: ywrO [H]

Synonym: Sama_1391

Alternate gene names: 119774528

Gene position: 1682171-1682764 (Clockwise)

Preceding gene: 119774527

Following gene: 119774529

Centisome position: 39.06

GC content: 57.24

Gene sequence:

>594_bases
ATGTCATCTGTTTTGCTGCTGTTTGCCCATCCATCGCAACATAAATCGGAAGTGTGCATGCCCATGTACCGGGTTGCCCA
GTCTGTTCCCGGCGTGACCTGTGTGGATCTCTATGCCGATTACCCCACATTTAACATCGACATTGTCACAGAGCAGCAGC
GTCTTGCCGCCCATCAAGGGGTTATCTGGCTTTTTCCGCTTTATTGGTATTCCACCCCCGCCATCCTAAAGGAATGGCAG
GATCTGGTGCTTGAGTATGGTTTTGCCTATGGCCCGGGTGGGACAAAGCTGCACGGGAAATCCCTGCTCTGCGCCCTGAG
TGCGGGTGGCAGCGAAGGTTCATATTGTGCCGAGGGTTACAATCATTTTGGCCTGAGACAACTCTTGTCGCCCATCGAGC
AGACCGCGTCCCTTATCGGCATGGACTACCTGCCACCTTTTGCGCTCTTTGGAGCCCGCTCGGCGGTGGAGGAGGGGCGG
CTAGGGCCCCATCTCGCGCGGTGGCGACAGCTGCTGGAAGCGCTGGTGGCTGGTGAAATACCGGATACCGCTTGTGGGGC
TGGGGTACCGGCAAAGCGGGAGACCTTGTCATGA

Upstream 100 bases:

>100_bases
GTCATCAATGCAAACTGGTTTGCCAGGCTCCTTCAGACCCGTCTTTGCCCATTCCTCAATAACCCCAGGGTGTGAGAGTT
CATCAGGGAGCTGTGAACCT

Downstream 100 bases:

>100_bases
CCGGGATTTTTCTGCAGGCCTTTGTTTACCTGCTTGCGGCTGTGCTTGCGGTGCCCCTTGCCAAACGTTTGGGGCTGGGC
TCTGTGCTCGGTTACCTGGT

Product: putative NAD(P)H oxidoreductase

Products: NAD(P); reduced acceptor [C]

Alternate protein names: GSP14 [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSSVLLLFAHPSQHKSEVCMPMYRVAQSVPGVTCVDLYADYPTFNIDIVTEQQRLAAHQGVIWLFPLYWYSTPAILKEWQ
DLVLEYGFAYGPGGTKLHGKSLLCALSAGGSEGSYCAEGYNHFGLRQLLSPIEQTASLIGMDYLPPFALFGARSAVEEGR
LGPHLARWRQLLEALVAGEIPDTACGAGVPAKRETLS

Sequences:

>Translated_197_residues
MSSVLLLFAHPSQHKSEVCMPMYRVAQSVPGVTCVDLYADYPTFNIDIVTEQQRLAAHQGVIWLFPLYWYSTPAILKEWQ
DLVLEYGFAYGPGGTKLHGKSLLCALSAGGSEGSYCAEGYNHFGLRQLLSPIEQTASLIGMDYLPPFALFGARSAVEEGR
LGPHLARWRQLLEALVAGEIPDTACGAGVPAKRETLS
>Mature_196_residues
SSVLLLFAHPSQHKSEVCMPMYRVAQSVPGVTCVDLYADYPTFNIDIVTEQQRLAAHQGVIWLFPLYWYSTPAILKEWQD
LVLEYGFAYGPGGTKLHGKSLLCALSAGGSEGSYCAEGYNHFGLRQLLSPIEQTASLIGMDYLPPFALFGARSAVEEGRL
GPHLARWRQLLEALVAGEIPDTACGAGVPAKRETLS

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=144, Percent_Identity=39.5833333333333, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786231, Length=146, Percent_Identity=43.1506849315069, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789750, Length=152, Percent_Identity=40.7894736842105, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21520; Mature: 21389

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVLLLFAHPSQHKSEVCMPMYRVAQSVPGVTCVDLYADYPTFNIDIVTEQQRLAAHQG
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECHHHHHHHCC
VIWLFPLYWYSTPAILKEWQDLVLEYGFAYGPGGTKLHGKSLLCALSAGGSEGSYCAEGY
CCEEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCCCCHHHHCC
NHFGLRQLLSPIEQTASLIGMDYLPPFALFGARSAVEEGRLGPHLARWRQLLEALVAGEI
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PDTACGAGVPAKRETLS
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSVLLLFAHPSQHKSEVCMPMYRVAQSVPGVTCVDLYADYPTFNIDIVTEQQRLAAHQG
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECHHHHHHHCC
VIWLFPLYWYSTPAILKEWQDLVLEYGFAYGPGGTKLHGKSLLCALSAGGSEGSYCAEGY
CCEEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCCCCHHHHCC
NHFGLRQLLSPIEQTASLIGMDYLPPFALFGARSAVEEGRLGPHLARWRQLLEALVAGEI
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PDTACGAGVPAKRETLS
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 9298659 [H]