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The map label for this gene is aer [H]

Identifier: 119774132

GI number: 119774132

Start: 1206764

End: 1208317

Strand: Reverse

Name: aer [H]

Synonym: Sama_0995

Alternate gene names: 119774132

Gene position: 1208317-1206764 (Counterclockwise)

Preceding gene: 119774134

Following gene: 119774131

Centisome position: 28.06

GC content: 56.76

Gene sequence:

>1554_bases
ATGTCGAACATGTCGAAACATCGCCCTATCAACCAACGTGAAATTCGCCTCAATCAGGATGACGAGTTGATTTCTACCAC
AGATTTGCGTGGCGTCATCACCTATGCCAACCCACGCTTTATTCAGATAAGCGGTTATAGCAAGCAGGAACTTGTGGGGC
ACTCCCACAATATTGTGCGTCACCCGGATATGCCGGCAGACGCCTTTGCTGAACTCTGGAGCAAGCTCAAAGCCGGTCAG
TCCTGGCGCGGCCTAGTGAAAAACCGCGCCAAAGATGGCAGCTTTTATTGGGTGGATGCCTTTGTGACGCCCATCTTTGA
GGCAGGCAAAATCGTCGGCTATCAGTCGGTGCGCCGCATGCCGCAGACCGAGTGGGTCAATCGCGCCACCCGTATTTATC
AGCGACTGCAACAGGGTAAGGGGTTGCCCCGTCACCTTTCCCTTGGGCAAAAACGCATTATTTCCGCCCTGGTTGCCACC
ACGGGCTTAGGTATATGTGGCCTGCTGTGGGGCCCGGGCGTAATGGTGGCCGGCGCGCTCTTGATGGGGGTCAATCTCGC
CATTTTCTACGATGAAGCGTTTCGCATTCCTGCCCGCCTGATGGCATTGCAACAGGAGTTCGACTCGGTCAGCCGCCACG
TCTATTGCGGCTATGACACCTCCTCTATTCTGGACTTTCAGCTGTTGCTGCAACAGGCCCGCATGCAGGGCGTGCTTGGC
CGCAGTCAGGATCAGGCGTTGCAATTACAGCGCATCGCCGAAAACCTGGTGGTTGCCAGTGGGCAAACCGAGGCCAGTCT
CGATATGCAACACAGGCAGTTGGAGCAACTGGCCTGCGCCATGGAAGAAATGACGGCCACCATAGGCGAAGTGGCACTCA
ACAGTCGCCAGACCTCGGAGAAAATTCGTGACGCCCAACAGCTGTGCCAACACAATGCCCATGCCATGTCTGAAAAGCGT
GTCCGGATTGCCAACCTCGCAGACGCTGTGGCAGAAGCGGCCAGCAATGCCGAAAAATTAAATCGTGAGGCCGAAAAAGT
GGCCAGCGCCATGTCTGAAATCGATGCCATCGCCGAGCAAACCAATTTACTGGCCCTGAATGCAGCCATTGAAGCCGCCA
GAGCCGGCGAGCAGGGACGCGGCTTTGCCGTCGTCGCCGACGAAGTGCGCGCCCTGTCGTCCCGCACCCAGCAGTCCACC
ATGAGCATTTCGCGCAGTGTCGAGCAGATGTTCAGCATGCTGGGAAGCTGGGCCGAAGAGATGGGCCGCAGCCAGCAGGA
GGCAGAGGCCTGTGCCCGCGCAATTGCCGAAAGCGTTGATGACATTCAGAATATTCATGTGCAGATAAGTGAAATCCACG
ACTTCGCCGAACAAAACGCCGTAGCCTCAGCCCAGCAGGAAACCGTGGTGGCAGACATGAACCAAAACCTGCAACAAATT
GCCCACGGCGCCAATGACAACCTGGCTGCCATGAGTCTGGTGGGCAAAGCCACCCTGGAACTGCAATCCAGCGCCGATAA
GGCCAGCAGCCTTCGCCAAACCTTTGGCCACTAA

Upstream 100 bases:

>100_bases
CTAAATCGGAGTAAAACCCTGATCAAATTATGGTTAAGTTATGCTACATTGATCGCCTTTTTCCAACCCATAATAATCTC
CAGAGCCGACGGCCGTATCT

Downstream 100 bases:

>100_bases
GGTATTTACCATCTAATGAGTGGCTTATCCAAGCCTTCCGGGGCAGGCAAAAAACGCCTGCCCATTTTCAAGAAACCTGC
TTTAAACATTTTAAAAACAC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSNMSKHRPINQREIRLNQDDELISTTDLRGVITYANPRFIQISGYSKQELVGHSHNIVRHPDMPADAFAELWSKLKAGQ
SWRGLVKNRAKDGSFYWVDAFVTPIFEAGKIVGYQSVRRMPQTEWVNRATRIYQRLQQGKGLPRHLSLGQKRIISALVAT
TGLGICGLLWGPGVMVAGALLMGVNLAIFYDEAFRIPARLMALQQEFDSVSRHVYCGYDTSSILDFQLLLQQARMQGVLG
RSQDQALQLQRIAENLVVASGQTEASLDMQHRQLEQLACAMEEMTATIGEVALNSRQTSEKIRDAQQLCQHNAHAMSEKR
VRIANLADAVAEAASNAEKLNREAEKVASAMSEIDAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQST
MSISRSVEQMFSMLGSWAEEMGRSQQEAEACARAIAESVDDIQNIHVQISEIHDFAEQNAVASAQQETVVADMNQNLQQI
AHGANDNLAAMSLVGKATLELQSSADKASSLRQTFGH

Sequences:

>Translated_517_residues
MSNMSKHRPINQREIRLNQDDELISTTDLRGVITYANPRFIQISGYSKQELVGHSHNIVRHPDMPADAFAELWSKLKAGQ
SWRGLVKNRAKDGSFYWVDAFVTPIFEAGKIVGYQSVRRMPQTEWVNRATRIYQRLQQGKGLPRHLSLGQKRIISALVAT
TGLGICGLLWGPGVMVAGALLMGVNLAIFYDEAFRIPARLMALQQEFDSVSRHVYCGYDTSSILDFQLLLQQARMQGVLG
RSQDQALQLQRIAENLVVASGQTEASLDMQHRQLEQLACAMEEMTATIGEVALNSRQTSEKIRDAQQLCQHNAHAMSEKR
VRIANLADAVAEAASNAEKLNREAEKVASAMSEIDAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQST
MSISRSVEQMFSMLGSWAEEMGRSQQEAEACARAIAESVDDIQNIHVQISEIHDFAEQNAVASAQQETVVADMNQNLQQI
AHGANDNLAAMSLVGKATLELQSSADKASSLRQTFGH
>Mature_516_residues
SNMSKHRPINQREIRLNQDDELISTTDLRGVITYANPRFIQISGYSKQELVGHSHNIVRHPDMPADAFAELWSKLKAGQS
WRGLVKNRAKDGSFYWVDAFVTPIFEAGKIVGYQSVRRMPQTEWVNRATRIYQRLQQGKGLPRHLSLGQKRIISALVATT
GLGICGLLWGPGVMVAGALLMGVNLAIFYDEAFRIPARLMALQQEFDSVSRHVYCGYDTSSILDFQLLLQQARMQGVLGR
SQDQALQLQRIAENLVVASGQTEASLDMQHRQLEQLACAMEEMTATIGEVALNSRQTSEKIRDAQQLCQHNAHAMSEKRV
RIANLADAVAEAASNAEKLNREAEKVASAMSEIDAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTM
SISRSVEQMFSMLGSWAEEMGRSQQEAEACARAIAESVDDIQNIHVQISEIHDFAEQNAVASAQQETVVADMNQNLQQIA
HGANDNLAAMSLVGKATLELQSSADKASSLRQTFGH

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=480, Percent_Identity=32.9166666666667, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788194, Length=264, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI2367378, Length=311, Percent_Identity=31.8327974276527, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788195, Length=219, Percent_Identity=35.6164383561644, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787690, Length=172, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56932; Mature: 56801

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNMSKHRPINQREIRLNQDDELISTTDLRGVITYANPRFIQISGYSKQELVGHSHNIVR
CCCCCCCCCCCCHHEEECCCCCCEECCCCCEEEEECCCCEEEEECCCHHHHHCCCCCCCC
HPDMPADAFAELWSKLKAGQSWRGLVKNRAKDGSFYWVDAFVTPIFEAGKIVGYQSVRRM
CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCHHCHHHHHCC
PQTEWVNRATRIYQRLQQGKGLPRHLSLGQKRIISALVATTGLGICGLLWGPGVMVAGAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LMGVNLAIFYDEAFRIPARLMALQQEFDSVSRHVYCGYDTSSILDFQLLLQQARMQGVLG
HHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHCC
RSQDQALQLQRIAENLVVASGQTEASLDMQHRQLEQLACAMEEMTATIGEVALNSRQTSE
CCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KIRDAQQLCQHNAHAMSEKRVRIANLADAVAEAASNAEKLNREAEKVASAMSEIDAIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTMSISRSVEQMFSMLGSWAEE
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGRSQQEAEACARAIAESVDDIQNIHVQISEIHDFAEQNAVASAQQETVVADMNQNLQQI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGANDNLAAMSLVGKATLELQSSADKASSLRQTFGH
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNMSKHRPINQREIRLNQDDELISTTDLRGVITYANPRFIQISGYSKQELVGHSHNIVR
CCCCCCCCCCCHHEEECCCCCCEECCCCCEEEEECCCCEEEEECCCHHHHHCCCCCCCC
HPDMPADAFAELWSKLKAGQSWRGLVKNRAKDGSFYWVDAFVTPIFEAGKIVGYQSVRRM
CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCHHCHHHHHCC
PQTEWVNRATRIYQRLQQGKGLPRHLSLGQKRIISALVATTGLGICGLLWGPGVMVAGAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LMGVNLAIFYDEAFRIPARLMALQQEFDSVSRHVYCGYDTSSILDFQLLLQQARMQGVLG
HHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHCC
RSQDQALQLQRIAENLVVASGQTEASLDMQHRQLEQLACAMEEMTATIGEVALNSRQTSE
CCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KIRDAQQLCQHNAHAMSEKRVRIANLADAVAEAASNAEKLNREAEKVASAMSEIDAIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTMSISRSVEQMFSMLGSWAEE
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGRSQQEAEACARAIAESVDDIQNIHVQISEIHDFAEQNAVASAQQETVVADMNQNLQQI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGANDNLAAMSLVGKATLELQSSADKASSLRQTFGH
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]