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The map label for this gene is ywaD [H]

Identifier: 119774056

GI number: 119774056

Start: 1111402

End: 1112805

Strand: Reverse

Name: ywaD [H]

Synonym: Sama_0919

Alternate gene names: 119774056

Gene position: 1112805-1111402 (Counterclockwise)

Preceding gene: 119774058

Following gene: 119774052

Centisome position: 25.84

GC content: 54.7

Gene sequence:

>1404_bases
ATGAAAACCCTACCTAAGCTTCTGGCCGGAGTCGGCCTGATTGCACTCACGGCCCCTTTGGGCGCATTTTCATCGGACGA
TATAAATCAGAAAGTTGCAGAACAACTGGCACAAAAAGCCCAGTCTTCTTCCCTCGGCTATGACATCGTAGAGTCTTTAA
CAGTTGAAGTGGGTCCGAGACTTGCGGGCAGTGAGCAGGATAAGGTGGCTGTGGACTGGGCGATTGCCAAGTTGCAAAGC
CTGGGATTTGACCGGGTTTATAAGGAACCCGTAACGGTTCCCGTTTGGCGCCGAGGTATTGCCAAAGCCAGCATTCTAAG
CCCATTTCCACAACCTCTCGTGGTAACCGCACTGGGCGGCAGTATAGCCACACCAGCTCAGGGACTCAGCGCCACCATTG
TGCGGTTTGATACCCTTCAAGACTTACAAAATGCAGAAGCTGGCAGCCTGAATGACAAAATTGCCTTTATCGATGCCAAA
ACGGAGCGTCACCGAGACGGAAAAGGCTATGGACAAACCGCTTCCGGCCGCAGTCGCGGCGCCGTAGCCGCTGCAGAAAA
AGGCGCTGTGGGTATCATCATCCGCTCCATCGGCACAGATCATGACCGTATGGCCCATACCGGCATGATGCGCTATGAGG
AAGGCGTGACCGCGATTCCTGCCGCCGCCATCTCCAACCCGGATGCCGACCTGATAAATGCCATGCTCAAGCGCGACAAA
GAAGTCGTGATTTCATTGGAGCTTGGCTCAGAGCGCCGTGGCGAAACCACGTCCTACAATGTGATAGCCGAAGTCAAAGG
CAGCACCAAAGCCGATGAGATTGTGCTGATTGGCGCACACCTTGACTCCTGGGACGAGGGAACCGGCGCCATCGATGATG
GTGCCGGCGTTGCCATTGTGACTGCAGCTGCCAAACACATTCTCGACCTGCCACAAAAACCGGAACGGACCATTCGCGTA
GTACTCTATGCCGCAGAGGAACTCGGATTGTTAGGCGGAAAAACCTATGCCAAAGAACACGAAGCCGAGCTGGAGAAGCA
CTATATCGCGGCCGAGTCAGACTTCGGCGCAGGCCCTATTTATCAAATTGATTGGCGGGTGGCTGACACGGCTCACTCTC
CTGTAATCAACGCCATGAAGGTAGCTGAACCTTTGGGCGTAGCGGCTGGAAATAACAAGGCTTCAGGAGGCCCGGACGTC
TCTATGTTGCCCGCTCTGGGCGTACCAGTTGCTTCACTTCGACAGGATGGCAGCGATTACTTTGACTATCACCACACGCC
CAATGACACGCTGGACAAGATTAACCCCGAGGCGCTGGCACAAAACGTGGCCGTATATGCGCAATTTGCGTGGGTGATGG
CAAACAGCAAAGTCGAACTGCGCCCCTTGCCCCCCAAGGAATAA

Upstream 100 bases:

>100_bases
AATATAGCCTTGGCTTACAGACTTCGTCGGGACACAGCCCACACTTTTTGTTAGATTGTTTTCAAAAATGAGATGTACCT
AATAAAAATAGAGGAAACAC

Downstream 100 bases:

>100_bases
CACCTTGTCATTTGCATAGTAAAAATCCACCTGCATAGCAGGTGGCTTTGACACGGCCCCCTAAAAGGGGGCTTAAAAAC
TAACCTTCTAGCCCCAATGC

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKTLPKLLAGVGLIALTAPLGAFSSDDINQKVAEQLAQKAQSSSLGYDIVESLTVEVGPRLAGSEQDKVAVDWAIAKLQS
LGFDRVYKEPVTVPVWRRGIAKASILSPFPQPLVVTALGGSIATPAQGLSATIVRFDTLQDLQNAEAGSLNDKIAFIDAK
TERHRDGKGYGQTASGRSRGAVAAAEKGAVGIIIRSIGTDHDRMAHTGMMRYEEGVTAIPAAAISNPDADLINAMLKRDK
EVVISLELGSERRGETTSYNVIAEVKGSTKADEIVLIGAHLDSWDEGTGAIDDGAGVAIVTAAAKHILDLPQKPERTIRV
VLYAAEELGLLGGKTYAKEHEAELEKHYIAAESDFGAGPIYQIDWRVADTAHSPVINAMKVAEPLGVAAGNNKASGGPDV
SMLPALGVPVASLRQDGSDYFDYHHTPNDTLDKINPEALAQNVAVYAQFAWVMANSKVELRPLPPKE

Sequences:

>Translated_467_residues
MKTLPKLLAGVGLIALTAPLGAFSSDDINQKVAEQLAQKAQSSSLGYDIVESLTVEVGPRLAGSEQDKVAVDWAIAKLQS
LGFDRVYKEPVTVPVWRRGIAKASILSPFPQPLVVTALGGSIATPAQGLSATIVRFDTLQDLQNAEAGSLNDKIAFIDAK
TERHRDGKGYGQTASGRSRGAVAAAEKGAVGIIIRSIGTDHDRMAHTGMMRYEEGVTAIPAAAISNPDADLINAMLKRDK
EVVISLELGSERRGETTSYNVIAEVKGSTKADEIVLIGAHLDSWDEGTGAIDDGAGVAIVTAAAKHILDLPQKPERTIRV
VLYAAEELGLLGGKTYAKEHEAELEKHYIAAESDFGAGPIYQIDWRVADTAHSPVINAMKVAEPLGVAAGNNKASGGPDV
SMLPALGVPVASLRQDGSDYFDYHHTPNDTLDKINPEALAQNVAVYAQFAWVMANSKVELRPLPPKE
>Mature_467_residues
MKTLPKLLAGVGLIALTAPLGAFSSDDINQKVAEQLAQKAQSSSLGYDIVESLTVEVGPRLAGSEQDKVAVDWAIAKLQS
LGFDRVYKEPVTVPVWRRGIAKASILSPFPQPLVVTALGGSIATPAQGLSATIVRFDTLQDLQNAEAGSLNDKIAFIDAK
TERHRDGKGYGQTASGRSRGAVAAAEKGAVGIIIRSIGTDHDRMAHTGMMRYEEGVTAIPAAAISNPDADLINAMLKRDK
EVVISLELGSERRGETTSYNVIAEVKGSTKADEIVLIGAHLDSWDEGTGAIDDGAGVAIVTAAAKHILDLPQKPERTIRV
VLYAAEELGLLGGKTYAKEHEAELEKHYIAAESDFGAGPIYQIDWRVADTAHSPVINAMKVAEPLGVAAGNNKASGGPDV
SMLPALGVPVASLRQDGSDYFDYHHTPNDTLDKINPEALAQNVAVYAQFAWVMANSKVELRPLPPKE

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Homo sapiens, GI7706387, Length=401, Percent_Identity=32.9177057356608, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 49538; Mature: 49538

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPKLLAGVGLIALTAPLGAFSSDDINQKVAEQLAQKAQSSSLGYDIVESLTVEVGPR
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
LAGSEQDKVAVDWAIAKLQSLGFDRVYKEPVTVPVWRRGIAKASILSPFPQPLVVTALGG
CCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCHHHHHCCCCCCCEEEEECCC
SIATPAQGLSATIVRFDTLQDLQNAEAGSLNDKIAFIDAKTERHRDGKGYGQTASGRSRG
CCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCCC
AVAAAEKGAVGIIIRSIGTDHDRMAHTGMMRYEEGVTAIPAAAISNPDADLINAMLKRDK
CEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCC
EVVISLELGSERRGETTSYNVIAEVKGSTKADEIVLIGAHLDSWDEGTGAIDDGAGVAIV
EEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEHH
TAAAKHILDLPQKPERTIRVVLYAAEELGLLGGKTYAKEHEAELEKHYIAAESDFGAGPI
HHHHHHHHCCCCCCCCEEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCE
YQIDWRVADTAHSPVINAMKVAEPLGVAAGNNKASGGPDVSMLPALGVPVASLRQDGSDY
EEEEEEEECCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCEECCCCCCCHHHHHCCCCCC
FDYHHTPNDTLDKINPEALAQNVAVYAQFAWVMANSKVELRPLPPKE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHEEEEEECCEEEECCCCCCC
>Mature Secondary Structure
MKTLPKLLAGVGLIALTAPLGAFSSDDINQKVAEQLAQKAQSSSLGYDIVESLTVEVGPR
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
LAGSEQDKVAVDWAIAKLQSLGFDRVYKEPVTVPVWRRGIAKASILSPFPQPLVVTALGG
CCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCHHHHHCCCCCCCEEEEECCC
SIATPAQGLSATIVRFDTLQDLQNAEAGSLNDKIAFIDAKTERHRDGKGYGQTASGRSRG
CCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCCC
AVAAAEKGAVGIIIRSIGTDHDRMAHTGMMRYEEGVTAIPAAAISNPDADLINAMLKRDK
CEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCC
EVVISLELGSERRGETTSYNVIAEVKGSTKADEIVLIGAHLDSWDEGTGAIDDGAGVAIV
EEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEHH
TAAAKHILDLPQKPERTIRVVLYAAEELGLLGGKTYAKEHEAELEKHYIAAESDFGAGPI
HHHHHHHHCCCCCCCCEEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCE
YQIDWRVADTAHSPVINAMKVAEPLGVAAGNNKASGGPDVSMLPALGVPVASLRQDGSDY
EEEEEEEECCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCEECCCCCCCHHHHHCCCCCC
FDYHHTPNDTLDKINPEALAQNVAVYAQFAWVMANSKVELRPLPPKE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHEEEEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]