Click here to switch to the map view.

The map label for this gene is pilC [H]

Identifier: 119773598

GI number: 119773598

Start: 565019

End: 566239

Strand: Direct

Name: pilC [H]

Synonym: Sama_0458

Alternate gene names: 119773598

Gene position: 565019-566239 (Clockwise)

Preceding gene: 119773597

Following gene: 119773599

Centisome position: 13.12

GC content: 54.71

Gene sequence:

>1221_bases
ATGCCGGTGTACAAGTATCGGGGGCGAAACGCCCAGGGACAGCAGGTAACAGGAGAGCTTGATGCTGCCTCCGAGAATGC
CGCCGCCGATCAGTTGCTGTCGCGGGCGGTTATCCCGCTGGAATTTCGCGAAACCAAGCCCCGTGGCGAAGGCGTAAGCG
TATCCAGCTTGTTTCGTCGCAGGGTCAGTTTGGAAGAGCTGCAGATTTTTACCCGGCAGATGTATTCACTGACCCGCTCG
GGGATCCCGATTCTCAGAGCCATTGCGGGGCTTAGCGAAACCACCCATTCTCAGCAAATGAAGCAGGCGCTGGATGATAT
TTCTGTGCAGCTGACTGCGGGCAGGCCTCTGTCATCGGCGATGAACCATCATCCCGAGGTGTTTGATGCCCTGTTTGTTT
CCATGGTGCATGTGGGCGAAAACACCGGTAAGTTGGAAGACGTCTTTTTGCAGTTGTCGGGTTATCTTGAGCGCGAGCAG
GAAACCCGTCGCCGCATCAAGTCAGCCGTCCGTTACCCCACATTTGTGCTGATTGCTATCTCTCTGGCCATGGTGATTTT
AAACATTATGGTGATCCCAAAGTTTGCCGACATGTTTTCCCGGTTTGGCGCCGAGTTGCCCTGGGCGACCCGGATTCTGA
TTGCCACATCCAATTTTTTCGTCAACTACTGGTGGCTGCTGGCACTGCTCGTGGTGGGACTGATTGGTGGTCTCGCCTAC
TGGCACAAAACAGAGCAAGGAGAAAAAAAATGGGACCAGTGGAAGCTGCATATGCCGGCGGTGGGTTCCATTATTGAACG
TTCTACCCTGTCTCGCTATTGCCGCAGCTTTGCCATGATGATGGGCGCCGGTGTTCCCATGACACAGGCTCTGAGCTTGG
TTGCCGATGCTGTGGACAACGCTTACATGCACGACAAGATAGTGGCCATGCGCCGCGGGATTGAGTCCGGCGAATCCATG
TTGCGGGTGTCTAACCACAGTAAACTCTTTACCCCGCTGGTGCTGCAGATGGTGGCCGTGGGGGAAGAAACCGGACAGCT
GGAACAGCTCCTTAACGATGCGGCCGATTTTTACGAAGGTGAAGTGGACTACGACCTGAAAAATCTCACCGCCAAGCTTG
AGCCCATACTTATCGGCATAGTGGCTGGCATTGTGCTCATTCTGGCACTGGGTATCTACCTGCCCATGTGGGACATGCTC
AATGTGGTCAAGGGAGGCTGA

Upstream 100 bases:

>100_bases
CCACGATAGAAGAGGTTGCCAGACTGGTGGAGGATGTCAGCGAAACCCAGATACCACTGTCGCAGGAAATGGCCCAGTTT
GATGGTGCAGGAGCCTGACG

Downstream 100 bases:

>100_bases
ACCTTGTTACCACAGCGGGAAGCCGAAGGAGAACTGATTGGTATCTATCGCCGCATGCTGGCGGTGATAGTGATGCTGTT
ACTGCTGGCGGTCGTGGGGA

Product: MSHA biogenesis protein MshG

Products: NA

Alternate protein names: Type IV-A pilus assembly protein pilC [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MPVYKYRGRNAQGQQVTGELDAASENAAADQLLSRAVIPLEFRETKPRGEGVSVSSLFRRRVSLEELQIFTRQMYSLTRS
GIPILRAIAGLSETTHSQQMKQALDDISVQLTAGRPLSSAMNHHPEVFDALFVSMVHVGENTGKLEDVFLQLSGYLEREQ
ETRRRIKSAVRYPTFVLIAISLAMVILNIMVIPKFADMFSRFGAELPWATRILIATSNFFVNYWWLLALLVVGLIGGLAY
WHKTEQGEKKWDQWKLHMPAVGSIIERSTLSRYCRSFAMMMGAGVPMTQALSLVADAVDNAYMHDKIVAMRRGIESGESM
LRVSNHSKLFTPLVLQMVAVGEETGQLEQLLNDAADFYEGEVDYDLKNLTAKLEPILIGIVAGIVLILALGIYLPMWDML
NVVKGG

Sequences:

>Translated_406_residues
MPVYKYRGRNAQGQQVTGELDAASENAAADQLLSRAVIPLEFRETKPRGEGVSVSSLFRRRVSLEELQIFTRQMYSLTRS
GIPILRAIAGLSETTHSQQMKQALDDISVQLTAGRPLSSAMNHHPEVFDALFVSMVHVGENTGKLEDVFLQLSGYLEREQ
ETRRRIKSAVRYPTFVLIAISLAMVILNIMVIPKFADMFSRFGAELPWATRILIATSNFFVNYWWLLALLVVGLIGGLAY
WHKTEQGEKKWDQWKLHMPAVGSIIERSTLSRYCRSFAMMMGAGVPMTQALSLVADAVDNAYMHDKIVAMRRGIESGESM
LRVSNHSKLFTPLVLQMVAVGEETGQLEQLLNDAADFYEGEVDYDLKNLTAKLEPILIGIVAGIVLILALGIYLPMWDML
NVVKGG
>Mature_405_residues
PVYKYRGRNAQGQQVTGELDAASENAAADQLLSRAVIPLEFRETKPRGEGVSVSSLFRRRVSLEELQIFTRQMYSLTRSG
IPILRAIAGLSETTHSQQMKQALDDISVQLTAGRPLSSAMNHHPEVFDALFVSMVHVGENTGKLEDVFLQLSGYLEREQE
TRRRIKSAVRYPTFVLIAISLAMVILNIMVIPKFADMFSRFGAELPWATRILIATSNFFVNYWWLLALLVVGLIGGLAYW
HKTEQGEKKWDQWKLHMPAVGSIIERSTLSRYCRSFAMMMGAGVPMTQALSLVADAVDNAYMHDKIVAMRRGIESGESML
RVSNHSKLFTPLVLQMVAVGEETGQLEQLLNDAADFYEGEVDYDLKNLTAKLEPILIGIVAGIVLILALGIYLPMWDMLN
VVKGG

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=27.020202020202, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786295, Length=407, Percent_Identity=25.7985257985258, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45358; Mature: 45227

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVYKYRGRNAQGQQVTGELDAASENAAADQLLSRAVIPLEFRETKPRGEGVSVSSLFRR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
RVSLEELQIFTRQMYSLTRSGIPILRAIAGLSETTHSQQMKQALDDISVQLTAGRPLSSA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHH
MNHHPEVFDALFVSMVHVGENTGKLEDVFLQLSGYLEREQETRRRIKSAVRYPTFVLIAI
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SLAMVILNIMVIPKFADMFSRFGAELPWATRILIATSNFFVNYWWLLALLVVGLIGGLAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
WHKTEQGEKKWDQWKLHMPAVGSIIERSTLSRYCRSFAMMMGAGVPMTQALSLVADAVDN
HHCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AYMHDKIVAMRRGIESGESMLRVSNHSKLFTPLVLQMVAVGEETGQLEQLLNDAADFYEG
HHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
EVDYDLKNLTAKLEPILIGIVAGIVLILALGIYLPMWDMLNVVKGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVYKYRGRNAQGQQVTGELDAASENAAADQLLSRAVIPLEFRETKPRGEGVSVSSLFRR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
RVSLEELQIFTRQMYSLTRSGIPILRAIAGLSETTHSQQMKQALDDISVQLTAGRPLSSA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHH
MNHHPEVFDALFVSMVHVGENTGKLEDVFLQLSGYLEREQETRRRIKSAVRYPTFVLIAI
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SLAMVILNIMVIPKFADMFSRFGAELPWATRILIATSNFFVNYWWLLALLVVGLIGGLAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
WHKTEQGEKKWDQWKLHMPAVGSIIERSTLSRYCRSFAMMMGAGVPMTQALSLVADAVDN
HHCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AYMHDKIVAMRRGIESGESMLRVSNHSKLFTPLVLQMVAVGEETGQLEQLLNDAADFYEG
HHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
EVDYDLKNLTAKLEPILIGIVAGIVLILALGIYLPMWDMLNVVKGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10024587; 10952301 [H]