Click here to switch to the map view.

The map label for this gene is argS

Identifier: 119773583

GI number: 119773583

Start: 545443

End: 547188

Strand: Reverse

Name: argS

Synonym: Sama_0443

Alternate gene names: 119773583

Gene position: 547188-545443 (Counterclockwise)

Preceding gene: 119773584

Following gene: 119773582

Centisome position: 12.71

GC content: 58.42

Gene sequence:

>1746_bases
ATGAAAGAACTCATTCAATCCTTGCTCGAACAAACCCTTGAATCCTTGAAAGCCCAGGGCATTGTGCCCGCCGACTTTGA
AGCGCGCATTCAGGTCGACCGAACTAAGGACAAGAGCCATGGCGATCTGGCCACCAATCTGGCCATGATGTTGACCAAGG
TTGCCGGTAAACCGCCACGTGAAATGGCGCAGCTCATCATCGACAACCTGCCCGCGTCCGCGCAGGTGGCCAAGGTCGAG
ATTGCTGGCCCCGGCTTTATCAACTTCTTTATCGACGACAACGCCCTGGCCAACCAGCTCAAGGCCGCGCTCGGCGATGC
CATGCTGGGCGTGAAAGCCGCAGCACCACAAACCGTGGTGGTGGACTACTCCTCCCCCAACCTCGCCAAGGAAATGCACG
TGGGTCACCTGCGTTCCACCATCATTGGCGACAGCGTAGTCCGCGCGCTGGAATTCCTCGGCCATAAAGTCATCCGTCAA
AACCACGTGGGTGACTGGGGTACCCAGTTCGGCATGCTGCTGGCCTACATGGAAGAGCTGCGTGCCCAGGGCGATGACAA
GGCCAATCTGGAGCTGTCAGACCTAGAAAGCTTCTACCGTGCGGCCAAGCTGCGTTTTGACGAATCCGACGAATTCGCCA
CCCGCGCCCGTCAGTTGGTGGTTGAGCTGCAAAGCGGTGATGCTTACTGCAACAAGCTGTGGCGCGAGTTCAACGACATC
TCCCTGAGCCACTGTCATGACGTGTATGCGCGTTTGGGTGTGAGCCTGACCCGTAAAGATGTACACGGTGAGAGCGCCTA
CAACGCCGACCTCGCTCAGGTTGTGGCCGATCTGGATGCCAAGGGCCTGCTCGCCATCAGTGACGGCGCCAAGGTGGTAT
TCCAGGAAGAGTTCCGTAACAAAGATGGCGAGCCACTGCCGGTGATTATCCAGAAGGCCGATGGCGGCTTCCTGTATGCC
ACGACCGATCTGGCCGCCATGCGCTACCGCTCAGGTGTGCTGAATGCCGACCGTGTGCTCTACTTTGTAGACCTGCGTCA
GGCGCTGCACTTCCAGCAGGTATTCAGCCTGGCCCGCACCGCAGGTTTCGTGCGTGACAACATGACCCTCGAGCACATGG
GCTTTGGCACCATGAACGGCGAAGACGGTCGTCCCTTCAAGACCCGCTCCGGCGGCGTGGTGAAGCTGGTTGACCTGCTC
GATGAAGCCGTTGAGCGTGCCGAGCAGCTGGTTCGCAGTAAAAACCCCGATATGGATGAAACTGAAGTCAAAGAAATCGC
CCGCGTGGTTGGCATTGCCTCGGTAAAATACGCCGACCTGTCCAAGAACCGCAGCAGCGATTACATCTTCAGCTTCGAGC
AGATGCTGAGCTTCGAAGGCAACACAGCCCCCTATCTGCTGTACGCTTACACCCGTGTGGCCGGTATCTTCAAGAAAGCC
GAAAACATCGACCTGACCAACGCCGAGCTGGTGCTGGATCATGACAAAGAGAAAGAGCTGGGCAACAAGCTGGCACAGTT
CGGTGAAATCCTTGCACGCATGGTGGACAAGGGCCAACCGCACATTCTCTGTGGTTACCTGTACGAGTTGGCTGGCGCCT
TCTCCAGCTTCTACGAGGCCTGCCCGGTGCTGAGCGCCGACAGCGAAACCGCCCGCGACAGCCGTTTGCTGCTATCGCGC
CTGACCGCCGACACCCTCAAGCAGGGCCTGTCGCTGCTCGGCATCGAGACTCTGGAGCGCATGTAA

Upstream 100 bases:

>100_bases
TTGCTCAAAAAGTTCCTTCAGCCAATAGCCAGCCGGGGGGCGCAGAGGCTACAATTCCCGGTTATTCCCGTTAAACCTTG
CAGTCAATAGATACAGGCCG

Downstream 100 bases:

>100_bases
TCCATGAGTCGCGATTACGCCAACCGAGCGCCACGGAGTAAAGGTCGTGGCAGCAACAAGAATGCCCGCTCGCCGGGGCA
CAAGCCCTGGATCGCGCTGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MKELIQSLLEQTLESLKAQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKPPREMAQLIIDNLPASAQVAKVE
IAGPGFINFFIDDNALANQLKAALGDAMLGVKAAAPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAQGDDKANLELSDLESFYRAAKLRFDESDEFATRARQLVVELQSGDAYCNKLWREFNDI
SLSHCHDVYARLGVSLTRKDVHGESAYNADLAQVVADLDAKGLLAISDGAKVVFQEEFRNKDGEPLPVIIQKADGGFLYA
TTDLAAMRYRSGVLNADRVLYFVDLRQALHFQQVFSLARTAGFVRDNMTLEHMGFGTMNGEDGRPFKTRSGGVVKLVDLL
DEAVERAEQLVRSKNPDMDETEVKEIARVVGIASVKYADLSKNRSSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKKA
ENIDLTNAELVLDHDKEKELGNKLAQFGEILARMVDKGQPHILCGYLYELAGAFSSFYEACPVLSADSETARDSRLLLSR
LTADTLKQGLSLLGIETLERM

Sequences:

>Translated_581_residues
MKELIQSLLEQTLESLKAQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKPPREMAQLIIDNLPASAQVAKVE
IAGPGFINFFIDDNALANQLKAALGDAMLGVKAAAPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAQGDDKANLELSDLESFYRAAKLRFDESDEFATRARQLVVELQSGDAYCNKLWREFNDI
SLSHCHDVYARLGVSLTRKDVHGESAYNADLAQVVADLDAKGLLAISDGAKVVFQEEFRNKDGEPLPVIIQKADGGFLYA
TTDLAAMRYRSGVLNADRVLYFVDLRQALHFQQVFSLARTAGFVRDNMTLEHMGFGTMNGEDGRPFKTRSGGVVKLVDLL
DEAVERAEQLVRSKNPDMDETEVKEIARVVGIASVKYADLSKNRSSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKKA
ENIDLTNAELVLDHDKEKELGNKLAQFGEILARMVDKGQPHILCGYLYELAGAFSSFYEACPVLSADSETARDSRLLLSR
LTADTLKQGLSLLGIETLERM
>Mature_581_residues
MKELIQSLLEQTLESLKAQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKPPREMAQLIIDNLPASAQVAKVE
IAGPGFINFFIDDNALANQLKAALGDAMLGVKAAAPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAQGDDKANLELSDLESFYRAAKLRFDESDEFATRARQLVVELQSGDAYCNKLWREFNDI
SLSHCHDVYARLGVSLTRKDVHGESAYNADLAQVVADLDAKGLLAISDGAKVVFQEEFRNKDGEPLPVIIQKADGGFLYA
TTDLAAMRYRSGVLNADRVLYFVDLRQALHFQQVFSLARTAGFVRDNMTLEHMGFGTMNGEDGRPFKTRSGGVVKLVDLL
DEAVERAEQLVRSKNPDMDETEVKEIARVVGIASVKYADLSKNRSSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKKA
ENIDLTNAELVLDHDKEKELGNKLAQFGEILARMVDKGQPHILCGYLYELAGAFSSFYEACPVLSADSETARDSRLLLSR
LTADTLKQGLSLLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=570, Percent_Identity=40.1754385964912, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI197100773, Length=517, Percent_Identity=31.3346228239845, Blast_Score=199, Evalue=7e-51,
Organism=Escherichia coli, GI1788184, Length=580, Percent_Identity=55, Blast_Score=643, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=598, Percent_Identity=36.9565217391304, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI71985068, Length=558, Percent_Identity=38.3512544802867, Blast_Score=348, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI17532153, Length=488, Percent_Identity=29.0983606557377, Blast_Score=158, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=576, Percent_Identity=31.5972222222222, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6321883, Length=565, Percent_Identity=29.9115044247788, Blast_Score=219, Evalue=8e-58,
Organism=Drosophila melanogaster, GI18859963, Length=606, Percent_Identity=39.4389438943894, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=32.2981366459627, Blast_Score=200, Evalue=3e-51,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SHEAM (A1S2P7)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926323.1
- ProteinModelPortal:   A1S2P7
- STRING:   A1S2P7
- GeneID:   4602698
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0443
- NMPDR:   fig|326297.7.peg.417
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   A1S2P7
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64311; Mature: 64311

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELIQSLLEQTLESLKAQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKPPR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
EMAQLIIDNLPASAQVAKVEIAGPGFINFFIDDNALANQLKAALGDAMLGVKAAAPQTVV
HHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAQGDDKANLELSDLESFYRAAKLRFDESDEFATRARQLVVELQSGDAYCNKLWREFNDI
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLSHCHDVYARLGVSLTRKDVHGESAYNADLAQVVADLDAKGLLAISDGAKVVFQEEFRN
CHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEHHHHCC
KDGEPLPVIIQKADGGFLYATTDLAAMRYRSGVLNADRVLYFVDLRQALHFQQVFSLART
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCHHHHEEHHHHHHHHHHHHHHHHHHH
AGFVRDNMTLEHMGFGTMNGEDGRPFKTRSGGVVKLVDLLDEAVERAEQLVRSKNPDMDE
HHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TEVKEIARVVGIASVKYADLSKNRSSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKKA
HHHHHHHHHHHHHHEEEHHCCCCCCCCHHEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ENIDLTNAELVLDHDKEKELGNKLAQFGEILARMVDKGQPHILCGYLYELAGAFSSFYEA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CPVLSADSETARDSRLLLSRLTADTLKQGLSLLGIETLERM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKELIQSLLEQTLESLKAQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKPPR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
EMAQLIIDNLPASAQVAKVEIAGPGFINFFIDDNALANQLKAALGDAMLGVKAAAPQTVV
HHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAQGDDKANLELSDLESFYRAAKLRFDESDEFATRARQLVVELQSGDAYCNKLWREFNDI
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLSHCHDVYARLGVSLTRKDVHGESAYNADLAQVVADLDAKGLLAISDGAKVVFQEEFRN
CHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEHHHHCC
KDGEPLPVIIQKADGGFLYATTDLAAMRYRSGVLNADRVLYFVDLRQALHFQQVFSLART
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCHHHHEEHHHHHHHHHHHHHHHHHHH
AGFVRDNMTLEHMGFGTMNGEDGRPFKTRSGGVVKLVDLLDEAVERAEQLVRSKNPDMDE
HHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TEVKEIARVVGIASVKYADLSKNRSSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKKA
HHHHHHHHHHHHHHEEEHHCCCCCCCCHHEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ENIDLTNAELVLDHDKEKELGNKLAQFGEILARMVDKGQPHILCGYLYELAGAFSSFYEA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CPVLSADSETARDSRLLLSRLTADTLKQGLSLLGIETLERM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA