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The map label for this gene is ldc [H]

Identifier: 119773550

GI number: 119773550

Start: 506845

End: 508020

Strand: Direct

Name: ldc [H]

Synonym: Sama_0410

Alternate gene names: 119773550

Gene position: 506845-508020 (Clockwise)

Preceding gene: 119773547

Following gene: 119773552

Centisome position: 11.77

GC content: 50.51

Gene sequence:

>1176_bases
ATGAGCCAGTTTCAATCTATTGACGTTGCTGATTTTTACGATAGTGAAACCTTTGCACGAATTCAGGAATTCGCCAAAGA
CAAGGCAACCCCTTTTGTGGTGATTGATACCAATATCATCGCGAAACAATACGATGACATGGTGACCAACTTCCCGTTTG
CCAACGTTTATTATGCAGTTAAGGCCAATCCCGCCAAAGAGATCCTGACCCTGCTGAAAGATAAAGGCTCCAACTTTGAT
ATCGCATCTATCTACGAGCTGGATATGGTGATGGCCGTCGGTGTGACTGCGGATCGCGTCAGCTTCGGCAACACCATCAA
AAAACGCAAAGATGTCCGTGCCTTTTATGAGCGTGGCGTGCGTTTGTTTGCTTCTGACTCTGAGGCCGATTTGCGCATGA
TTGCCGAAGAAGCCCCTGGCTCTAAAGTGTATGTGCGTATCCTGACAGAAGGTTCGCAAACCGCTGACTGGCCGTTGTCG
CGCAAGTTCGGTTGCCAAAATGAAATGGCCTATGAGTTGCTGGCGCTGGCAAAAGAGCTGGGCCTGGATCCTTATGGCAT
ATCCTTCCACGTGGGTTCTCAGCAGCGCGATATCGGTGCCTGGGATGCCGCCATCGGTAAGGTGAAGGTACTGTTCGATC
GTCTGCGTGAAGATCACGGTATTGTGCTGAAGATGATTAACATGGGTGGCGGTTTCCCGGCCAACTACATAGACAAGACC
AATCAACTCGGTGTTTACGCTCAGCAAATCAAACACTTCCTTAAGGAAGACTTTGGTGATGAGCTGCCTGAAATCATTCT
GGAGCCTGGTCGCTCGCTGATTTCAAATGCCGGCGTGCTCATTTCTGAAGTGGTACTTATCAGCCGTAAGTCTCACACTG
CGCTGGAGCGTTGGGTATACACAGATGTGGGTAAATTCTCAGGTCTGATTGAGACCATGGACGAAGCCATCAAATACCCC
ATCTTCACCGAAAAGAAGGGTGAACTGGACAAGTGTGTGATTGCCGGACCAACCTGTGACAGTGCCGACATCATGTATGA
GCACTATGCCTATGGTTTGCCGGCGGATCTCGCCATCGGTGACCGCCTGTACTGGCTGACCGCCGGTGCCTACACCACCA
CCTACTCGGCGGTGTGTTTTAACGGCTTCCCGCCGCTCAAGGATTACTACCTGTAA

Upstream 100 bases:

>100_bases
AATTCGTTGCATCTTCAGCGAAAATAGCGTCTACTTCGCACGTTTTTTACCATCACATTGATGCCATCCACTCGGGCTAA
GTACAGGAGAACCAAGGCCA

Downstream 100 bases:

>100_bases
TCGGCGTTTCCGGCGAAACCGTAATACAAAAAGAAGGGTGCCATTAAGGCACCCTTTATTTTTGAAGCCAGCTGGCAGTT
GGACATCAGTTGTCGTATGA

Product: ornithine decarboxylase

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSQFQSIDVADFYDSETFARIQEFAKDKATPFVVIDTNIIAKQYDDMVTNFPFANVYYAVKANPAKEILTLLKDKGSNFD
IASIYELDMVMAVGVTADRVSFGNTIKKRKDVRAFYERGVRLFASDSEADLRMIAEEAPGSKVYVRILTEGSQTADWPLS
RKFGCQNEMAYELLALAKELGLDPYGISFHVGSQQRDIGAWDAAIGKVKVLFDRLREDHGIVLKMINMGGGFPANYIDKT
NQLGVYAQQIKHFLKEDFGDELPEIILEPGRSLISNAGVLISEVVLISRKSHTALERWVYTDVGKFSGLIETMDEAIKYP
IFTEKKGELDKCVIAGPTCDSADIMYEHYAYGLPADLAIGDRLYWLTAGAYTTTYSAVCFNGFPPLKDYYL

Sequences:

>Translated_391_residues
MSQFQSIDVADFYDSETFARIQEFAKDKATPFVVIDTNIIAKQYDDMVTNFPFANVYYAVKANPAKEILTLLKDKGSNFD
IASIYELDMVMAVGVTADRVSFGNTIKKRKDVRAFYERGVRLFASDSEADLRMIAEEAPGSKVYVRILTEGSQTADWPLS
RKFGCQNEMAYELLALAKELGLDPYGISFHVGSQQRDIGAWDAAIGKVKVLFDRLREDHGIVLKMINMGGGFPANYIDKT
NQLGVYAQQIKHFLKEDFGDELPEIILEPGRSLISNAGVLISEVVLISRKSHTALERWVYTDVGKFSGLIETMDEAIKYP
IFTEKKGELDKCVIAGPTCDSADIMYEHYAYGLPADLAIGDRLYWLTAGAYTTTYSAVCFNGFPPLKDYYL
>Mature_390_residues
SQFQSIDVADFYDSETFARIQEFAKDKATPFVVIDTNIIAKQYDDMVTNFPFANVYYAVKANPAKEILTLLKDKGSNFDI
ASIYELDMVMAVGVTADRVSFGNTIKKRKDVRAFYERGVRLFASDSEADLRMIAEEAPGSKVYVRILTEGSQTADWPLSR
KFGCQNEMAYELLALAKELGLDPYGISFHVGSQQRDIGAWDAAIGKVKVLFDRLREDHGIVLKMINMGGGFPANYIDKTN
QLGVYAQQIKHFLKEDFGDELPEIILEPGRSLISNAGVLISEVVLISRKSHTALERWVYTDVGKFSGLIETMDEAIKYPI
FTEKKGELDKCVIAGPTCDSADIMYEHYAYGLPADLAIGDRLYWLTAGAYTTTYSAVCFNGFPPLKDYYL

Specific function: Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency [H]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Homo sapiens, GI4505489, Length=387, Percent_Identity=30.2325581395349, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI16506287, Length=368, Percent_Identity=25.5434782608696, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI22538418, Length=381, Percent_Identity=25.7217847769029, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI21361583, Length=381, Percent_Identity=25.7217847769029, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562780, Length=372, Percent_Identity=29.8387096774194, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322664, Length=400, Percent_Identity=29.75, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24586472, Length=359, Percent_Identity=29.8050139275766, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24586474, Length=350, Percent_Identity=30.2857142857143, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- InterPro:   IPR002433 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.17; =4.1.1.18 [H]

Molecular weight: Translated: 43784; Mature: 43653

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFQSIDVADFYDSETFARIQEFAKDKATPFVVIDTNIIAKQYDDMVTNFPFANVYYAV
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEE
KANPAKEILTLLKDKGSNFDIASIYELDMVMAVGVTADRVSFGNTIKKRKDVRAFYERGV
ECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCC
RLFASDSEADLRMIAEEAPGSKVYVRILTEGSQTADWPLSRKFGCQNEMAYELLALAKEL
EEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLDPYGISFHVGSQQRDIGAWDAAIGKVKVLFDRLREDHGIVLKMINMGGGFPANYIDKT
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCC
NQLGVYAQQIKHFLKEDFGDELPEIILEPGRSLISNAGVLISEVVLISRKSHTALERWVY
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TDVGKFSGLIETMDEAIKYPIFTEKKGELDKCVIAGPTCDSADIMYEHYAYGLPADLAIG
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEC
DRLYWLTAGAYTTTYSAVCFNGFPPLKDYYL
CEEEEEECCCHHHEEHEEEECCCCCHHHCCC
>Mature Secondary Structure 
SQFQSIDVADFYDSETFARIQEFAKDKATPFVVIDTNIIAKQYDDMVTNFPFANVYYAV
CCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEE
KANPAKEILTLLKDKGSNFDIASIYELDMVMAVGVTADRVSFGNTIKKRKDVRAFYERGV
ECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCC
RLFASDSEADLRMIAEEAPGSKVYVRILTEGSQTADWPLSRKFGCQNEMAYELLALAKEL
EEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLDPYGISFHVGSQQRDIGAWDAAIGKVKVLFDRLREDHGIVLKMINMGGGFPANYIDKT
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCC
NQLGVYAQQIKHFLKEDFGDELPEIILEPGRSLISNAGVLISEVVLISRKSHTALERWVY
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TDVGKFSGLIETMDEAIKYPIFTEKKGELDKCVIAGPTCDSADIMYEHYAYGLPADLAIG
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEC
DRLYWLTAGAYTTTYSAVCFNGFPPLKDYYL
CEEEEEECCCHHHEEHEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11073919 [H]