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The map label for this gene is lepB [H]

Identifier: 119717478

GI number: 119717478

Start: 3455747

End: 3456550

Strand: Reverse

Name: lepB [H]

Synonym: Noca_3254

Alternate gene names: 119717478

Gene position: 3456550-3455747 (Counterclockwise)

Preceding gene: 119717479

Following gene: 119717477

Centisome position: 69.33

GC content: 67.54

Gene sequence:

>804_bases
GTGACTTCCGAAGACCGCGACTCCACGTCCGTCGCCGAACCCGACGAGACCGGAGCGCGGTCTTCGCACTCCCCGGCACC
CGCCTCGAAGCCCGCCAAGAAGAAGCACCTGCCGGTCTGGCAGGAGACGATCCTGCTCCTCGGCATCGCCGTCGTGCTGG
CGATCGTCATCAAGGCGCTGTTCGTCCAGGCCTTCTACATCCCGTCGCAGTCGATGGAGCCCGGTCTGGTCAAGAACGAC
CGGATCCTGGTACAGAAGGTGTCCTACTGGTTCGGCGGCGGCCCCGAGCGCGGGGACGTCGTCGTGTTCAAGGACCCGGG
CGGCTGGCTGACCGCCGAGGAGTCGGCCGGGCCGACCAACGGGGTCGCGAAGCTGCTGTCCAAGGTGGGCCTCTACCCCT
CCGGCGGCCACCTGGTGAAGCGGGTCATCGGGGTCGCGGGCGACACCGTCTCCTGCTGCGACGTCCGGGGCCGGATCGAG
GTCAACGGCCAGCCGCTCGACGAGAAGGACTACGCGCGGCTCGACGGGGCGGAGTGCTACGGCCCGATGGTCGACGGCTG
CGACAAGGACTGGGAGATCGGGCCCATCCCGGCGGGCCACATCTTCGTGATGGGCGACAACCGCAACAACTCCGCCGACT
CCTCCTTCCACATGTGCAAGCCGAGCGAGACCGACTGCACCAAGAACCCGTACGTCGACGTCGGTGACGTGGTCGGCAAG
GTGTTCGTGCTGCTCTGGCCCAGTGATCACTTCAAGTTCCTGCATCGTCCCGACACCTTCGCGGGCGTGCCCGACCCGTC
CTAG

Upstream 100 bases:

>100_bases
GCTCTACTACCTGCGCAACCTGCGCGGCAAGAAGGCGAAGATCAAGGAGCGCCGCGAGGCCTGAGCGAGATTTCTCAGGC
AGCCTGACTACGCTTCCCGC

Downstream 100 bases:

>100_bases
CGCCGTGACCGAGCCAGCGCCATGAGCGAGCTGCCCCGCGGATCCACGATCCGCAAGGACGCCGGCCTGTACGGCTACGA
GCGGGCCCTGCGCCGGCACG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTSEDRDSTSVAEPDETGARSSHSPAPASKPAKKKHLPVWQETILLLGIAVVLAIVIKALFVQAFYIPSQSMEPGLVKND
RILVQKVSYWFGGGPERGDVVVFKDPGGWLTAEESAGPTNGVAKLLSKVGLYPSGGHLVKRVIGVAGDTVSCCDVRGRIE
VNGQPLDEKDYARLDGAECYGPMVDGCDKDWEIGPIPAGHIFVMGDNRNNSADSSFHMCKPSETDCTKNPYVDVGDVVGK
VFVLLWPSDHFKFLHRPDTFAGVPDPS

Sequences:

>Translated_267_residues
MTSEDRDSTSVAEPDETGARSSHSPAPASKPAKKKHLPVWQETILLLGIAVVLAIVIKALFVQAFYIPSQSMEPGLVKND
RILVQKVSYWFGGGPERGDVVVFKDPGGWLTAEESAGPTNGVAKLLSKVGLYPSGGHLVKRVIGVAGDTVSCCDVRGRIE
VNGQPLDEKDYARLDGAECYGPMVDGCDKDWEIGPIPAGHIFVMGDNRNNSADSSFHMCKPSETDCTKNPYVDVGDVVGK
VFVLLWPSDHFKFLHRPDTFAGVPDPS
>Mature_266_residues
TSEDRDSTSVAEPDETGARSSHSPAPASKPAKKKHLPVWQETILLLGIAVVLAIVIKALFVQAFYIPSQSMEPGLVKNDR
ILVQKVSYWFGGGPERGDVVVFKDPGGWLTAEESAGPTNGVAKLLSKVGLYPSGGHLVKRVIGVAGDTVSCCDVRGRIEV
NGQPLDEKDYARLDGAECYGPMVDGCDKDWEIGPIPAGHIFVMGDNRNNSADSSFHMCKPSETDCTKNPYVDVGDVVGKV
FVLLWPSDHFKFLHRPDTFAGVPDPS

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28794; Mature: 28663

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEDRDSTSVAEPDETGARSSHSPAPASKPAKKKHLPVWQETILLLGIAVVLAIVIKAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVQAFYIPSQSMEPGLVKNDRILVQKVSYWFGGGPERGDVVVFKDPGGWLTAEESAGPTN
HHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCHH
GVAKLLSKVGLYPSGGHLVKRVIGVAGDTVSCCDVRGRIEVNGQPLDEKDYARLDGAECY
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHCCCHHHC
GPMVDGCDKDWEIGPIPAGHIFVMGDNRNNSADSSFHMCKPSETDCTKNPYVDVGDVVGK
CCHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCE
VFVLLWPSDHFKFLHRPDTFAGVPDPS
EEEEEECCHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure 
TSEDRDSTSVAEPDETGARSSHSPAPASKPAKKKHLPVWQETILLLGIAVVLAIVIKAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVQAFYIPSQSMEPGLVKNDRILVQKVSYWFGGGPERGDVVVFKDPGGWLTAEESAGPTN
HHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCHH
GVAKLLSKVGLYPSGGHLVKRVIGVAGDTVSCCDVRGRIEVNGQPLDEKDYARLDGAECY
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHCCCHHHC
GPMVDGCDKDWEIGPIPAGHIFVMGDNRNNSADSSFHMCKPSETDCTKNPYVDVGDVVGK
CCHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCE
VFVLLWPSDHFKFLHRPDTFAGVPDPS
EEEEEECCHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]