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The map label for this gene is pqqL [C]

Identifier: 119717400

GI number: 119717400

Start: 3373706

End: 3375067

Strand: Reverse

Name: pqqL [C]

Synonym: Noca_3176

Alternate gene names: 119717400

Gene position: 3375067-3373706 (Counterclockwise)

Preceding gene: 119717401

Following gene: 119717399

Centisome position: 67.69

GC content: 71.95

Gene sequence:

>1362_bases
GTGACGCCCCGGTCGGCCGAAGCCTCACCGGTGACCCGCCAGAGCAGCTCTGGCGGGTCACCGTCTTCCCGGGGCACGAC
GCGCACGCTGCAGACGACCACCGACGCCGACGGCCAGGTGACCTCGCGGGTGCGGCGTACGGTCCTGCCCTCGGGACTGC
GGGTGATCAGCGAGCACCAGGCGGGCGTCCGGTCCGCGGCGATCGGCGTGTGGGTGGGGGTCGGCTCGCGCGACGAGAGC
CCCAGCCTGCACGGCTGCTCGCACTTCCTCGAGCACCTGCTGTTCAAGGGCACGACGGAGCGCTCGGCGCTGGACATCTC
GGTGGCGCTGGACGCGGTGGGCGGTGAGTTCAACGCGTTCACCGCGAAGGAGTACACCTGCTTCCACGCCCGGGTGCTCG
ACGAGGACCTGCCGCTGGCCGTGGACGTGCTCGGAGACATGATCACCGCCTCGACGCTCACCGCCGAGGACGTCGAGGCC
GAGCGCGACGTGATCCTCGACGAGATCGCCATGCACGATGACGATCCTGACGACGTCGTGCACAACCTGTTCGCGGAGCA
GGCCTGGGGAGACACCCCGCTCGGCCGGCCGATCGCCGGCACCGTCGGCTCGATCCGCTCGCTCAGCCGCGACCAGGTGC
GCCGCTTCTACCGGCGTCACTACCGGCCCGCGAACGTCGTGGTCGCGGCCGCCGGGAACGTCGACCACGCCCAACTGGTG
CGCCAGGTCCGTACGGCGTTCGCCCGCAACGGCTGGCTCGACGGGCGCGACACTCCGGTGGTGCCGCGGCACGGCACCCG
CAAGCGGGTCCGGCCCGGGGTGCTCGCCACGACCCGGCCGTTCGAGCAGGTCAACGTGGTCCTCGGCATGGAGGGCCTGC
GCCGCGACGACGACCGCCGCTTCGCCCTGGGCGTGCTCAACACCGCCCTCGGCGGCGGCACCTCCTCGCGGCTGTTCCAG
GAGGTTCGCGAGCGTCGTGGGCTCGCGTACTCGGTCTTCTCCTTCGCCACCCACCACGCCGACTCAGGACTGGTCGGCGT
GTCGGTCGGCTGCCTGCCGAACAAGCTCGACGACGTCCTCGCCGTCGTGCGCGAGGAGCTGGCCAAGGTCGCCGAGTCCG
GCATCACGGCCGAGGAGCTGGCCCGCGGCAAGGGTCAGCTGCGGGGCGGGCTGGTGCTGGGGCTCGAGGACTCCGCGTCC
CGGATGTCCCGCATCGGCAAGGCCGAGCTGGTGCACGACCGGTTGATGAGCATCGACGAGGTGATCGCCCGCATCGACGG
CGTCACGCTCGAAGAGGTCCAGTCGATCGCGGCCGAGGTCTTCGCCCGGCCCGAGATCCTCGCGGTGGTCGGCCCGGCGT
AG

Upstream 100 bases:

>100_bases
AGATCGCCGAGATCGACGACCGCGGGAAGCTGTCGCTGGTCCCGGTCGTCGAGGGCGACCAGGCCGACTCCGACACCGCC
GAGGCCGGCTCCGAGGAGGA

Downstream 100 bases:

>100_bases
CGGATCGAGGTGGCCCCGAGCCAGGCCGGCCCGGCGGCTGGATCGCACGATCGACGACCGGCTGCACCGCCGCCTCGATG
CCGAGTCGGACGCGGCGCTG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTPRSAEASPVTRQSSSGGSPSSRGTTRTLQTTTDADGQVTSRVRRTVLPSGLRVISEHQAGVRSAAIGVWVGVGSRDES
PSLHGCSHFLEHLLFKGTTERSALDISVALDAVGGEFNAFTAKEYTCFHARVLDEDLPLAVDVLGDMITASTLTAEDVEA
ERDVILDEIAMHDDDPDDVVHNLFAEQAWGDTPLGRPIAGTVGSIRSLSRDQVRRFYRRHYRPANVVVAAAGNVDHAQLV
RQVRTAFARNGWLDGRDTPVVPRHGTRKRVRPGVLATTRPFEQVNVVLGMEGLRRDDDRRFALGVLNTALGGGTSSRLFQ
EVRERRGLAYSVFSFATHHADSGLVGVSVGCLPNKLDDVLAVVREELAKVAESGITAEELARGKGQLRGGLVLGLEDSAS
RMSRIGKAELVHDRLMSIDEVIARIDGVTLEEVQSIAAEVFARPEILAVVGPA

Sequences:

>Translated_453_residues
MTPRSAEASPVTRQSSSGGSPSSRGTTRTLQTTTDADGQVTSRVRRTVLPSGLRVISEHQAGVRSAAIGVWVGVGSRDES
PSLHGCSHFLEHLLFKGTTERSALDISVALDAVGGEFNAFTAKEYTCFHARVLDEDLPLAVDVLGDMITASTLTAEDVEA
ERDVILDEIAMHDDDPDDVVHNLFAEQAWGDTPLGRPIAGTVGSIRSLSRDQVRRFYRRHYRPANVVVAAAGNVDHAQLV
RQVRTAFARNGWLDGRDTPVVPRHGTRKRVRPGVLATTRPFEQVNVVLGMEGLRRDDDRRFALGVLNTALGGGTSSRLFQ
EVRERRGLAYSVFSFATHHADSGLVGVSVGCLPNKLDDVLAVVREELAKVAESGITAEELARGKGQLRGGLVLGLEDSAS
RMSRIGKAELVHDRLMSIDEVIARIDGVTLEEVQSIAAEVFARPEILAVVGPA
>Mature_452_residues
TPRSAEASPVTRQSSSGGSPSSRGTTRTLQTTTDADGQVTSRVRRTVLPSGLRVISEHQAGVRSAAIGVWVGVGSRDESP
SLHGCSHFLEHLLFKGTTERSALDISVALDAVGGEFNAFTAKEYTCFHARVLDEDLPLAVDVLGDMITASTLTAEDVEAE
RDVILDEIAMHDDDPDDVVHNLFAEQAWGDTPLGRPIAGTVGSIRSLSRDQVRRFYRRHYRPANVVVAAAGNVDHAQLVR
QVRTAFARNGWLDGRDTPVVPRHGTRKRVRPGVLATTRPFEQVNVVLGMEGLRRDDDRRFALGVLNTALGGGTSSRLFQE
VRERRGLAYSVFSFATHHADSGLVGVSVGCLPNKLDDVLAVVREELAKVAESGITAEELARGKGQLRGGLVLGLEDSASR
MSRIGKAELVHDRLMSIDEVIARIDGVTLEEVQSIAAEVFARPEILAVVGPA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=436, Percent_Identity=33.4862385321101, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI46593007, Length=468, Percent_Identity=30.7692307692308, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI24308013, Length=471, Percent_Identity=23.7791932059448, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI50592988, Length=415, Percent_Identity=22.6506024096386, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1787770, Length=411, Percent_Identity=21.1678832116788, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=414, Percent_Identity=29.2270531400966, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17553678, Length=425, Percent_Identity=28.7058823529412, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17510601, Length=441, Percent_Identity=22.4489795918367, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=425, Percent_Identity=32, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321813, Length=422, Percent_Identity=23.4597156398104, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319426, Length=427, Percent_Identity=22.7166276346604, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357875, Length=422, Percent_Identity=31.5165876777251, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24646943, Length=422, Percent_Identity=31.5165876777251, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI19921772, Length=434, Percent_Identity=25.8064516129032, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48845; Mature: 48713

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRSAEASPVTRQSSSGGSPSSRGTTRTLQTTTDADGQVTSRVRRTVLPSGLRVISEHQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHH
AGVRSAAIGVWVGVGSRDESPSLHGCSHFLEHLLFKGTTERSALDISVALDAVGGEFNAF
HHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCE
TAKEYTCFHARVLDEDLPLAVDVLGDMITASTLTAEDVEAERDVILDEIAMHDDDPDDVV
ECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHH
HNLFAEQAWGDTPLGRPIAGTVGSIRSLSRDQVRRFYRRHYRPANVVVAAAGNVDHAQLV
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
RQVRTAFARNGWLDGRDTPVVPRHGTRKRVRPGVLATTRPFEQVNVVLGMEGLRRDDDRR
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCEECCCCHHHHHHHCCCHHCCCCCCCH
FALGVLNTALGGGTSSRLFQEVRERRGLAYSVFSFATHHADSGLVGVSVGCLPNKLDDVL
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
AVVREELAKVAESGITAEELARGKGQLRGGLVLGLEDSASRMSRIGKAELVHDRLMSIDE
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHH
VIARIDGVTLEEVQSIAAEVFARPEILAVVGPA
HHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
TPRSAEASPVTRQSSSGGSPSSRGTTRTLQTTTDADGQVTSRVRRTVLPSGLRVISEHQ
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHH
AGVRSAAIGVWVGVGSRDESPSLHGCSHFLEHLLFKGTTERSALDISVALDAVGGEFNAF
HHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCE
TAKEYTCFHARVLDEDLPLAVDVLGDMITASTLTAEDVEAERDVILDEIAMHDDDPDDVV
ECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHH
HNLFAEQAWGDTPLGRPIAGTVGSIRSLSRDQVRRFYRRHYRPANVVVAAAGNVDHAQLV
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
RQVRTAFARNGWLDGRDTPVVPRHGTRKRVRPGVLATTRPFEQVNVVLGMEGLRRDDDRR
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCEECCCCHHHHHHHCCCHHCCCCCCCH
FALGVLNTALGGGTSSRLFQEVRERRGLAYSVFSFATHHADSGLVGVSVGCLPNKLDDVL
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
AVVREELAKVAESGITAEELARGKGQLRGGLVLGLEDSASRMSRIGKAELVHDRLMSIDE
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHH
VIARIDGVTLEEVQSIAAEVFARPEILAVVGPA
HHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]