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The map label for this gene is ctaD1 [H]

Identifier: 119717364

GI number: 119717364

Start: 3342432

End: 3344180

Strand: Reverse

Name: ctaD1 [H]

Synonym: Noca_3140

Alternate gene names: 119717364

Gene position: 3344180-3342432 (Counterclockwise)

Preceding gene: 119717365

Following gene: 119717363

Centisome position: 67.07

GC content: 67.18

Gene sequence:

>1749_bases
GTGACCGCCACCGCTGCACCGTCGACCACCATCACGGCACGCCCGCCGCTGGGTCAGCAGCTCGCGCGCATCATGACGAC
GACCGATCACAAGGTGATCGGCAAGCTCTACCTGGGCACGTCGTTCGCCTGGTTCCTGATCGGCGGCCTGATGGCCATGC
TGATCCGCTCGGAGCTGGCCTACCCGGGCATGCAGGTCGTGAACGACGAGGTCTACAACCAGCTGTTCACGATGCACGGC
ACGATCATGCTGCTGCTGTTCGCGACGCCGCTGTTCTTCGGCTTCGCCAACGTGATCATGCCGTTGCAGATCGGCTCGCC
CGACGTCGCCTTCCCGCGCCTGAACATGCTCAGCTACTGGCTGTTCCTGTTCGGCGGCCTGATCGCCGCGTCCGGCTTCC
TCACGCCCTCCGGCGCGGCCGACTTCGGCTGGTTCGCCTACACCCCGCTCTCCGACGCGGTGCGCTCGCCGGGCGTCGGC
GGCGACCTGTGGATCATGGGCCTGTGGATGGCCGGCCTCGGCACCATCCTCGGCGCGGTCAACTTCATCACCACGATCAT
CTGCATGCGCGCGCCCGGCATGACGATGTTCCGGATGCCGATCTTCGTGTGGAACACGCTGGTCACCAGCCTGCTCGCAC
TGATCGTCTTCCCGGTCCTCGCCGGCGCGCTGCTCTCGCTCGAGGCCGACCGCCAGCTGGGCGCCCACGTCTTCGACACC
TCGCACGGCGGCGCCATCTTGTGGCAGCACCTGTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATCGCGTTGCCGTT
CTTCGGCATCGTGACCGAGATCCTCCCGGTGTTCAGCCGCAAGCCGATCTTCGGCTACATCGGCCTGGTCGGCGCGACCC
TCGGCATCGCCGTCCTCTCGGTCGCCGTGTGGGCGCACCACATGTTCGTCACCGGCGCCGTGGACCTGCCGTTCTTCTCC
GGCATGACCTTCCTGATCGCCGTACCGACCGGGGTGAAGTTCTTCAACTGGATCGGCACGATGTGGGGCGGGTCGTTGTC
GTTCGACACCCCGATGCTGTGGTCGATCGGCTTCTTGACGACGTTCCTGTTCGGCGGCCTGACCGGCGTGATCCTGGCCA
GCCCGCCGCTGGACTTCCACGTCTCCGACTCCTACTTCGTGGTCGCGCACTTCCACTACGTCGTCTTCGGCACCGTCGTG
TTCGCGATGTTCGCCGGCTTCTACTACTGGTGGCCGAAGATGACCGGCCGGATGCTCGACGAGCGGCTCGGCCGGCTCCA
CTTCTGGCTGCTGTTCATCGGCTTCCACACCACGTTCCTGGTCCAGCACTGGCTCGGCGTCGAGGGCATGCCGCGGCGCT
ACGCCGACTACCTGCCGGGCGACGGCTTCACGACGCTCAACCAGGTGTCGACGATCGGCGCGTTCCTGCTCGGCGCCTCC
ACGCTGCCGTTCCTCTACAACGTCTACATCTCGCGTCGCTCGCCGCTGGTCACCACGGACGACCCGTGGGGCTGGGGCCG
GTCGCTGGAGTGGGCCACGAGCTGCCCGCCGCCGCGCCACAACTTCGTGACCATCCCGCGGATCCGCTCGGAGTCGCCGG
CGTTCGACCTGCACCACCCCGAGGTCGCGGCGATCGAGTTGGAGGACAACGAGGCCGCCCGGGTGGGCGCACCTGCCGAC
GCACCTGACATGGAGGGCCGCGAGGAGATGCTCCGCGACCGCAACACCGACCCGGAGGGCAACGCCTGA

Upstream 100 bases:

>100_bases
AGGACGCCGGTGCGACGTCGCAGGCGCCGCTGCTGGGCGGCGAGTACGCCAGCACGCAGGCCGGACTCGACTCCGGCGAC
CAGTCCGAGGAGGGCGCGGA

Downstream 100 bases:

>100_bases
TGAAGTCCGAGGCCTGGATCTTCGGGATCGTCACCATCTTCTTCGGGCTGATCAGCCCGGCGTACTGGTTCATGTCCTCG
GACTGGACCGGCACGTCCGC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-alpha; Cytochrome c oxidase polypeptide I-alpha [H]

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MTATAAPSTTITARPPLGQQLARIMTTTDHKVIGKLYLGTSFAWFLIGGLMAMLIRSELAYPGMQVVNDEVYNQLFTMHG
TIMLLLFATPLFFGFANVIMPLQIGSPDVAFPRLNMLSYWLFLFGGLIAASGFLTPSGAADFGWFAYTPLSDAVRSPGVG
GDLWIMGLWMAGLGTILGAVNFITTIICMRAPGMTMFRMPIFVWNTLVTSLLALIVFPVLAGALLSLEADRQLGAHVFDT
SHGGAILWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPIFGYIGLVGATLGIAVLSVAVWAHHMFVTGAVDLPFFS
GMTFLIAVPTGVKFFNWIGTMWGGSLSFDTPMLWSIGFLTTFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVV
FAMFAGFYYWWPKMTGRMLDERLGRLHFWLLFIGFHTTFLVQHWLGVEGMPRRYADYLPGDGFTTLNQVSTIGAFLLGAS
TLPFLYNVYISRRSPLVTTDDPWGWGRSLEWATSCPPPRHNFVTIPRIRSESPAFDLHHPEVAAIELEDNEAARVGAPAD
APDMEGREEMLRDRNTDPEGNA

Sequences:

>Translated_582_residues
MTATAAPSTTITARPPLGQQLARIMTTTDHKVIGKLYLGTSFAWFLIGGLMAMLIRSELAYPGMQVVNDEVYNQLFTMHG
TIMLLLFATPLFFGFANVIMPLQIGSPDVAFPRLNMLSYWLFLFGGLIAASGFLTPSGAADFGWFAYTPLSDAVRSPGVG
GDLWIMGLWMAGLGTILGAVNFITTIICMRAPGMTMFRMPIFVWNTLVTSLLALIVFPVLAGALLSLEADRQLGAHVFDT
SHGGAILWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPIFGYIGLVGATLGIAVLSVAVWAHHMFVTGAVDLPFFS
GMTFLIAVPTGVKFFNWIGTMWGGSLSFDTPMLWSIGFLTTFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVV
FAMFAGFYYWWPKMTGRMLDERLGRLHFWLLFIGFHTTFLVQHWLGVEGMPRRYADYLPGDGFTTLNQVSTIGAFLLGAS
TLPFLYNVYISRRSPLVTTDDPWGWGRSLEWATSCPPPRHNFVTIPRIRSESPAFDLHHPEVAAIELEDNEAARVGAPAD
APDMEGREEMLRDRNTDPEGNA
>Mature_581_residues
TATAAPSTTITARPPLGQQLARIMTTTDHKVIGKLYLGTSFAWFLIGGLMAMLIRSELAYPGMQVVNDEVYNQLFTMHGT
IMLLLFATPLFFGFANVIMPLQIGSPDVAFPRLNMLSYWLFLFGGLIAASGFLTPSGAADFGWFAYTPLSDAVRSPGVGG
DLWIMGLWMAGLGTILGAVNFITTIICMRAPGMTMFRMPIFVWNTLVTSLLALIVFPVLAGALLSLEADRQLGAHVFDTS
HGGAILWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPIFGYIGLVGATLGIAVLSVAVWAHHMFVTGAVDLPFFSG
MTFLIAVPTGVKFFNWIGTMWGGSLSFDTPMLWSIGFLTTFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVVF
AMFAGFYYWWPKMTGRMLDERLGRLHFWLLFIGFHTTFLVQHWLGVEGMPRRYADYLPGDGFTTLNQVSTIGAFLLGAST
LPFLYNVYISRRSPLVTTDDPWGWGRSLEWATSCPPPRHNFVTIPRIRSESPAFDLHHPEVAAIELEDNEAARVGAPADA
PDMEGREEMLRDRNTDPEGNA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=42.8007889546351, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=43.389199255121, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=39.292364990689, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=39.8148148148148, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=37.2, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 64330; Mature: 64199

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATAAPSTTITARPPLGQQLARIMTTTDHKVIGKLYLGTSFAWFLIGGLMAMLIRSELA
CCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPGMQVVNDEVYNQLFTMHGTIMLLLFATPLFFGFANVIMPLQIGSPDVAFPRLNMLSYW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHH
LFLFGGLIAASGFLTPSGAADFGWFAYTPLSDAVRSPGVGGDLWIMGLWMAGLGTILGAV
HHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NFITTIICMRAPGMTMFRMPIFVWNTLVTSLLALIVFPVLAGALLSLEADRQLGAHVFDT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SHGGAILWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPIFGYIGLVGATLGIAVLS
CCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VAVWAHHMFVTGAVDLPFFSGMTFLIAVPTGVKFFNWIGTMWGGSLSFDTPMLWSIGFLT
HHHHHHHHHHCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVVFAMFAGFYYWWPKMTGRMLD
HHHHHCHHEEEEECCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGRLHFWLLFIGFHTTFLVQHWLGVEGMPRRYADYLPGDGFTTLNQVSTIGAFLLGAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
TLPFLYNVYISRRSPLVTTDDPWGWGRSLEWATSCPPPRHNFVTIPRIRSESPAFDLHHP
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
EVAAIELEDNEAARVGAPADAPDMEGREEMLRDRNTDPEGNA
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TATAAPSTTITARPPLGQQLARIMTTTDHKVIGKLYLGTSFAWFLIGGLMAMLIRSELA
CCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPGMQVVNDEVYNQLFTMHGTIMLLLFATPLFFGFANVIMPLQIGSPDVAFPRLNMLSYW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHH
LFLFGGLIAASGFLTPSGAADFGWFAYTPLSDAVRSPGVGGDLWIMGLWMAGLGTILGAV
HHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NFITTIICMRAPGMTMFRMPIFVWNTLVTSLLALIVFPVLAGALLSLEADRQLGAHVFDT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SHGGAILWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPIFGYIGLVGATLGIAVLS
CCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VAVWAHHMFVTGAVDLPFFSGMTFLIAVPTGVKFFNWIGTMWGGSLSFDTPMLWSIGFLT
HHHHHHHHHHCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TFLFGGLTGVILASPPLDFHVSDSYFVVAHFHYVVFGTVVFAMFAGFYYWWPKMTGRMLD
HHHHHCHHEEEEECCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGRLHFWLLFIGFHTTFLVQHWLGVEGMPRRYADYLPGDGFTTLNQVSTIGAFLLGAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
TLPFLYNVYISRRSPLVTTDDPWGWGRSLEWATSCPPPRHNFVTIPRIRSESPAFDLHHP
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
EVAAIELEDNEAARVGAPADAPDMEGREEMLRDRNTDPEGNA
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]