| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is yxbG [H]
Identifier: 119716811
GI number: 119716811
Start: 2749674
End: 2750453
Strand: Reverse
Name: yxbG [H]
Synonym: Noca_2585
Alternate gene names: 119716811
Gene position: 2750453-2749674 (Counterclockwise)
Preceding gene: 119716812
Following gene: 119716810
Centisome position: 55.16
GC content: 69.87
Gene sequence:
>780_bases GTGACAGGACGCATCCAGGGCCGGGTCGCGGTCATCACCGGCGGCTGCTCCGGCATCGGTCTCGCGACGGTGCAGCGCTT CGTCCAGGAGGGCGCGAAGGTCGTCATCGGGGACATCGACGACGCGCGGGGGCACCAGCTGGTCGAGCAGCTGGGCGGCG CAGACGTGGCGACGTACGTCCACGTCGACGTCACCAGCAAGGAGCAGGTCGACGCGCTGTTCCAGACCGCGAAGGACGCC TACGGGTCGGTCGACATCGCGTTCAACAACGCCGGCATCAGCCCGCCGGAGGACGACTCGATCCTGGACACCGACCTGGA CGCCTGGCGCAAGGTGCAGGAGGTCAACCTGACCTCGGTCTACCTGTGCTGCAAGGCCGCCCTCCCCCACATGCTCGAGC AGGGCCGGGGCTCGATCATCAACACGGCGTCGTTCGTCGCGGTGATGGGGGCCGCGACCAGCCAGATCTCCTACTCGGCG TCGAAGGGCGGGGTGCTGTCGATGACCCGGGAGCTCGGCGTCCAGTTCGCGCGCCAGGGGGTGCGGGTCAACGCGCTGTG CCCGGGACCGGTGAACACGCCGCTGCTGCAGGAGCTGTTCGCCAAGGACGCCGAGCGGGCCGCCCGACGGCTCGTGCACG TGCCGATGGGGCGGTTCGGGGAGCCCGAGGAGATGGCGTCGGCGGTGCTGTTCCTCGCCTCGGACGACTCCTCGTTCATG ACCGCGAGCACGTTCCTGGTCGACGGCGGCATCTCCGGCGCCTACGTCACCCCGCTCTGA
Upstream 100 bases:
>100_bases GAGGAGAAGAACGTCTTCATTGCACACTAGGGGGCTCCGCCCCTAGTACCCCCACTGGGGGCTCCGCCCCCAGACCCCCA ACCGTGAGGAGATCGAGAGA
Downstream 100 bases:
>100_bases CGTGGTCGCCCCGGTCATCGGCCTGACCACCTACCGCGAGGAGGCGGCGTGGGGGGTCTGGCGCCAGCGCGCCGACCTGC TCCCCACGCAGTACGCCGCC
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYVHVDVTSKEQVDALFQTAKDA YGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCCKAALPHMLEQGRGSIINTASFVAVMGAATSQISYSA SKGGVLSMTRELGVQFARQGVRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFM TASTFLVDGGISGAYVTPL
Sequences:
>Translated_259_residues MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYVHVDVTSKEQVDALFQTAKDA YGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCCKAALPHMLEQGRGSIINTASFVAVMGAATSQISYSA SKGGVLSMTRELGVQFARQGVRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFM TASTFLVDGGISGAYVTPL >Mature_258_residues TGRIQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYVHVDVTSKEQVDALFQTAKDAY GSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCCKAALPHMLEQGRGSIINTASFVAVMGAATSQISYSAS KGGVLSMTRELGVQFARQGVRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFMT ASTFLVDGGISGAYVTPL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=35.5731225296443, Blast_Score=140, Evalue=8e-34, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=37.4468085106383, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=32.824427480916, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=32.421875, Blast_Score=124, Evalue=9e-29, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=36.046511627907, Blast_Score=120, Evalue=9e-28, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=29.6153846153846, Blast_Score=118, Evalue=4e-27, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=34.4961240310078, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=31.7460317460317, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=30.3846153846154, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=33.1707317073171, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI4504505, Length=244, Percent_Identity=29.5081967213115, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=28.5123966942149, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=33.1632653061224, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=31.3131313131313, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7706318, Length=209, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI142976729, Length=222, Percent_Identity=29.2792792792793, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=31.6091954022989, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4503301, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=5e-12, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=33.739837398374, Blast_Score=140, Evalue=6e-35, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.4110671936759, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=32.258064516129, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=33.8709677419355, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=30.8300395256917, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=33.7301587301587, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.2258064516129, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=31.640625, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=28.2258064516129, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=31.8897637795276, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=31.3725490196078, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=25.6410256410256, Blast_Score=72, Evalue=4e-14, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=36.2204724409449, Blast_Score=143, Evalue=1e-34, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=32.421875, Blast_Score=137, Evalue=5e-33, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=34, Blast_Score=131, Evalue=3e-31, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=33.0827067669173, Blast_Score=123, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=30.1960784313725, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=32.0610687022901, Blast_Score=113, Evalue=9e-26, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.2681992337165, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=29.5454545454545, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=29.3233082706767, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=31.640625, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=28.8461538461538, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=28.2527881040892, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=31.6981132075472, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.4615384615385, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.7984790874525, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.5735294117647, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.9961977186312, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=27.4809160305344, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=30.3149606299213, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.6923076923077, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=30.0751879699248, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.8625954198473, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=32.1782178217822, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=28.4090909090909, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=28.2828282828283, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.9795918367347, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=26.8199233716475, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17561272, Length=266, Percent_Identity=30.0751879699248, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=28.3505154639175, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=27.6679841897233, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508895, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555612, Length=251, Percent_Identity=25.4980079681275, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71997099, Length=228, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=32.6530612244898, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=1e-16, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=30.9803921568627, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-29, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.5381526104418, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=32.5581395348837, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.2, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=35.0253807106599, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI24644337, Length=193, Percent_Identity=35.2331606217617, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=29.5019157088123, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI281364892, Length=224, Percent_Identity=29.9107142857143, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=25.6281407035176, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21357673, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI281364494, Length=244, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331218, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=28.921568627451, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=204, Percent_Identity=28.921568627451, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21356301, Length=244, Percent_Identity=28.6885245901639, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI221510726, Length=186, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24581726, Length=228, Percent_Identity=28.5087719298246, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665264, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27326; Mature: 27195
Theoretical pI: Translated: 4.67; Mature: 4.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYV CCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEE HVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSV EEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHH YLCCKAALPHMLEQGRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELGVQFARQG HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCC VRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFM CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCEE TASTFLVDGGISGAYVTPL EEEEEEEECCCCCEEECCC >Mature Secondary Structure TGRIQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATYV CCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEE HVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSV EEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHH YLCCKAALPHMLEQGRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELGVQFARQG HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCC VRVNALCPGPVNTPLLQELFAKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFM CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCEE TASTFLVDGGISGAYVTPL EEEEEEEECCCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7584049; 9384377 [H]