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The map label for this gene is lspA [H]

Identifier: 119716435

GI number: 119716435

Start: 2355476

End: 2355997

Strand: Reverse

Name: lspA [H]

Synonym: Noca_2206

Alternate gene names: 119716435

Gene position: 2355997-2355476 (Counterclockwise)

Preceding gene: 119716436

Following gene: 119716434

Centisome position: 47.25

GC content: 69.54

Gene sequence:

>522_bases
GTGCGGACTGGTCGTGTCGTAGTCCTGTTGGCGGCGGCCACGGTTGCTGGGATCGACCTGACCGCGAAGGCGGTATCCGA
GGTCCAGCTGGCCAACTCTTCGGTCGATCTCGGGCTACTGCAGCTCAAATTGGCCCACAACTCCGGCGTCGCGTTCAGCA
TGGGCGACCGACTTCCGGTGGGCGTGATCGTGGCCATCACCGCGGCCATCGCCGTCACCCTGGCCGTGTACGCGTGGCGC
AGGGCCCCGCACGCCGGGTGGGTCGAGCGGATCGCCGGCGGAGCGGTCATCGGCGGCGCCCTCGCCAACGTGGTCGACCG
CGCCCGCGACGGCGTGGTCACCGACTACCTGCACACCGGCTGGTGGCCCACGTTCAACCTCGCCGACACATTCCTGGTCA
CCGGGTTCGTCGTGATCGCCGTGCTGCACGCCCGCCCAGAACGCACCAAGGAGACGGCTGCGGCGCCGGCGAAAAACCAC
ACCGCCGCCCGGCCGGTCACGAACGACCCTCCACGGACATAG

Upstream 100 bases:

>100_bases
CGCCGCCGGAACAGCCGCCCGTCGCTCCCGCGCCAGCGGAAGCCGGGGCCACGTGAGCCGGGGCCCGCTGAGCCGCGGTC
TAGCGGAGGCAGGCACGCGG

Downstream 100 bases:

>100_bases
CCATCGCCTCCAGTGCCCAGCAGCGCGAGCCTGGGCGCCATGAACTCGGCTGTCGTCGCCACCGAGCAGGCACAGACCCC
CTCGAGACCCAAGACGACGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MRTGRVVVLLAAATVAGIDLTAKAVSEVQLANSSVDLGLLQLKLAHNSGVAFSMGDRLPVGVIVAITAAIAVTLAVYAWR
RAPHAGWVERIAGGAVIGGALANVVDRARDGVVTDYLHTGWWPTFNLADTFLVTGFVVIAVLHARPERTKETAAAPAKNH
TAARPVTNDPPRT

Sequences:

>Translated_173_residues
MRTGRVVVLLAAATVAGIDLTAKAVSEVQLANSSVDLGLLQLKLAHNSGVAFSMGDRLPVGVIVAITAAIAVTLAVYAWR
RAPHAGWVERIAGGAVIGGALANVVDRARDGVVTDYLHTGWWPTFNLADTFLVTGFVVIAVLHARPERTKETAAAPAKNH
TAARPVTNDPPRT
>Mature_173_residues
MRTGRVVVLLAAATVAGIDLTAKAVSEVQLANSSVDLGLLQLKLAHNSGVAFSMGDRLPVGVIVAITAAIAVTLAVYAWR
RAPHAGWVERIAGGAVIGGALANVVDRARDGVVTDYLHTGWWPTFNLADTFLVTGFVVIAVLHARPERTKETAAAPAKNH
TAARPVTNDPPRT

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18104; Mature: 18104

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTGRVVVLLAAATVAGIDLTAKAVSEVQLANSSVDLGLLQLKLAHNSGVAFSMGDRLPV
CCCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEECCCCCCH
GVIVAITAAIAVTLAVYAWRRAPHAGWVERIAGGAVIGGALANVVDRARDGVVTDYLHTG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC
WWPTFNLADTFLVTGFVVIAVLHARPERTKETAAAPAKNHTAARPVTNDPPRT
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTGRVVVLLAAATVAGIDLTAKAVSEVQLANSSVDLGLLQLKLAHNSGVAFSMGDRLPV
CCCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEECCCCCCH
GVIVAITAAIAVTLAVYAWRRAPHAGWVERIAGGAVIGGALANVVDRARDGVVTDYLHTG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC
WWPTFNLADTFLVTGFVVIAVLHARPERTKETAAAPAKNHTAARPVTNDPPRT
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]