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The map label for this gene is ligC [H]

Identifier: 119715152

GI number: 119715152

Start: 948797

End: 949897

Strand: Reverse

Name: ligC [H]

Synonym: Noca_0907

Alternate gene names: 119715152

Gene position: 949897-948797 (Counterclockwise)

Preceding gene: 119715155

Following gene: 119715151

Centisome position: 19.05

GC content: 71.75

Gene sequence:

>1101_bases
ATGCAGCTGCCGGTGATGCCGCCCGTCCAGCCGATGCTCGCGAAGTCGGTCAAGGGGATCCCCGACCCCGAGAAGCACGG
GGGCCTGAGCTTCGAGCCGAAGTGGGACGGGTTCCGGTGCCTCGTGTTCAAGGACGGCGACGAGGTGGAGCTGGCCAGCC
GCAACACCAAGCCGCTGACCCGCTACTTCCCCGAGGTCGTCGCCGCGATGCGCGAGCAGCTGCCGCACCGCTGCGTGCTG
GACGGCGAGCTCTTCGTCGCGCTCCCGAACGACGCGGGGGTGGAGCGCCTGGAGTTCGAGGTGCTCCAGGAGCGGATCCA
CCCGGCCCGGTCCCGCATCGAGCTGCTGGCCGAGAAGACGCCGGCCTCGTACGTCGCGTTCGACCTGCTCGCGCTCGACG
ACGAGTCGTACGCCGAGCGGCCGTTCGCGGAGCGTCGCGCCGCCCTCGAGCGGGCGCTGGGCGACCTCGACGGGCCCTGC
TTCCTCACCCGCACCACCACGGATCCGGCGCAGGCCGAGGAGTGGTTCCACCAGTTCGAGGGCGCCGGCCTCGACGGCGT
GGTCGCCAAGCCCCTGGGGGCGGCGTACCAGCAGAACGCCCGCACCATGCTCAAGATCAAGCACGAGCGCACCGCCGACG
TGGTCGTCGCCGGCTACCGCGAGCACAAGACCAGCACCCCCGACAGGCCGTTGCTCGGCAGCCTGCTGCTCGGGCTGTAC
GCCGACGGCCAGCTCCAGCACGTCGGTGTGAGCGCCAGCTTCACCGCCGCCCGTCGCGCCGAGCTGATCGAGGAGCTGCA
GCCGCTCGTCGTGCCGATCGCGGACCACCCCTGGGGCGAGTGGGCCGACTGGGCGATCGCCAACCCGGACCGGGTGCCGG
GCACCCAGAGCCGGTGGAGCCAGGGCAAGGACCTCTCGTTCACCCCGCTGCGCCCCGAGCGGGTGCTGGAGGTCGCCTAC
GACCACATGGAGGGACGCCGGTTCCGCCACACCGCCCAGTTCCGGCGCTGGCGGCCCGACCGCGACCCGGAGTCGTGCGG
GTACGACCAACTGGAGGAGCCGGTGGGCTACGACCTCGCTAGGATCCTGAACGTCGACTGA

Upstream 100 bases:

>100_bases
CGGCCCAAGGTTACGGGTCGTGTGCCTGAGGACGCGCCATGGCGCGTCCTCAGGCACACGACCCACCTCCGAGAGCAGCC
GGCGCGGTTAGCCTCGGGGG

Downstream 100 bases:

>100_bases
TCCGACTCACCCGGCCGGCCGAGGAGGCACCACATGTCCGAGAACCCGTCCGAGAGCTCCTCAGGGGACTACGACGTCGT
GCTCCTGGTCGAGCAGGCCC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQLPVMPPVQPMLAKSVKGIPDPEKHGGLSFEPKWDGFRCLVFKDGDEVELASRNTKPLTRYFPEVVAAMREQLPHRCVL
DGELFVALPNDAGVERLEFEVLQERIHPARSRIELLAEKTPASYVAFDLLALDDESYAERPFAERRAALERALGDLDGPC
FLTRTTTDPAQAEEWFHQFEGAGLDGVVAKPLGAAYQQNARTMLKIKHERTADVVVAGYREHKTSTPDRPLLGSLLLGLY
ADGQLQHVGVSASFTAARRAELIEELQPLVVPIADHPWGEWADWAIANPDRVPGTQSRWSQGKDLSFTPLRPERVLEVAY
DHMEGRRFRHTAQFRRWRPDRDPESCGYDQLEEPVGYDLARILNVD

Sequences:

>Translated_366_residues
MQLPVMPPVQPMLAKSVKGIPDPEKHGGLSFEPKWDGFRCLVFKDGDEVELASRNTKPLTRYFPEVVAAMREQLPHRCVL
DGELFVALPNDAGVERLEFEVLQERIHPARSRIELLAEKTPASYVAFDLLALDDESYAERPFAERRAALERALGDLDGPC
FLTRTTTDPAQAEEWFHQFEGAGLDGVVAKPLGAAYQQNARTMLKIKHERTADVVVAGYREHKTSTPDRPLLGSLLLGLY
ADGQLQHVGVSASFTAARRAELIEELQPLVVPIADHPWGEWADWAIANPDRVPGTQSRWSQGKDLSFTPLRPERVLEVAY
DHMEGRRFRHTAQFRRWRPDRDPESCGYDQLEEPVGYDLARILNVD
>Mature_366_residues
MQLPVMPPVQPMLAKSVKGIPDPEKHGGLSFEPKWDGFRCLVFKDGDEVELASRNTKPLTRYFPEVVAAMREQLPHRCVL
DGELFVALPNDAGVERLEFEVLQERIHPARSRIELLAEKTPASYVAFDLLALDDESYAERPFAERRAALERALGDLDGPC
FLTRTTTDPAQAEEWFHQFEGAGLDGVVAKPLGAAYQQNARTMLKIKHERTADVVVAGYREHKTSTPDRPLLGSLLLGLY
ADGQLQHVGVSASFTAARRAELIEELQPLVVPIADHPWGEWADWAIANPDRVPGTQSRWSQGKDLSFTPLRPERVLEVAY
DHMEGRRFRHTAQFRRWRPDRDPESCGYDQLEEPVGYDLARILNVD

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=361, Percent_Identity=26.8698060941828, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85815841, Length=238, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 41282; Mature: 41282

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPVMPPVQPMLAKSVKGIPDPEKHGGLSFEPKWDGFRCLVFKDGDEVELASRNTKPLT
CCCCCCCCCHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHH
RYFPEVVAAMREQLPHRCVLDGELFVALPNDAGVERLEFEVLQERIHPARSRIELLAEKT
HHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PASYVAFDLLALDDESYAERPFAERRAALERALGDLDGPCFLTRTTTDPAQAEEWFHQFE
CCHHHEEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC
GAGLDGVVAKPLGAAYQQNARTMLKIKHERTADVVVAGYREHKTSTPDRPLLGSLLLGLY
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHCCCCCCCCHHHHHHHHHHH
ADGQLQHVGVSASFTAARRAELIEELQPLVVPIADHPWGEWADWAIANPDRVPGTQSRWS
CCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHC
QGKDLSFTPLRPERVLEVAYDHMEGRRFRHTAQFRRWRPDRDPESCGYDQLEEPVGYDLA
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHH
RILNVD
HHHCCC
>Mature Secondary Structure
MQLPVMPPVQPMLAKSVKGIPDPEKHGGLSFEPKWDGFRCLVFKDGDEVELASRNTKPLT
CCCCCCCCCHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHH
RYFPEVVAAMREQLPHRCVLDGELFVALPNDAGVERLEFEVLQERIHPARSRIELLAEKT
HHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PASYVAFDLLALDDESYAERPFAERRAALERALGDLDGPCFLTRTTTDPAQAEEWFHQFE
CCHHHEEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC
GAGLDGVVAKPLGAAYQQNARTMLKIKHERTADVVVAGYREHKTSTPDRPLLGSLLLGLY
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHCCCCCCCCHHHHHHHHHHH
ADGQLQHVGVSASFTAARRAELIEELQPLVVPIADHPWGEWADWAIANPDRVPGTQSRWS
CCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHC
QGKDLSFTPLRPERVLEVAYDHMEGRRFRHTAQFRRWRPDRDPESCGYDQLEEPVGYDLA
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHH
RILNVD
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA