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The map label for this gene is degP [C]

Identifier: 119715129

GI number: 119715129

Start: 922326

End: 923579

Strand: Reverse

Name: degP [C]

Synonym: Noca_0884

Alternate gene names: 119715129

Gene position: 923579-922326 (Counterclockwise)

Preceding gene: 119715132

Following gene: 119715123

Centisome position: 18.52

GC content: 72.25

Gene sequence:

>1254_bases
ATGAACGACCAGCCCACCAGTCCGCCTCCGGGACCGCCGAACCCGTACTTCTCCACCCCGGCGCCGCTGGGTCCGCCTCC
CCAGGGCCCGCCTCCCGGGGTGGCGCCGGACCCGCAGCCGGGGCAGCGTCGTCCTCGCCGGACCGGCCTCGCCGCCGCGG
TCGTCGCGACCGCGCTGGTGGCCGGCGGCGCGGCAGGGGTCGGCGGCGCCGCCGCCTGGAGCGCGCTCGACGATGGAGGC
TCGTCGAGCGCGGGCGGCCCCAGCAGCCGCACGACGGCGCAGGTCGTCGACACCCCCGACTCCGAGGCACCGGCCGGCTC
CGTCGAGCAGGTCGCTGCCAAGGTGCTGCCTTCGGTGGTCAAGATCGACGTGGCCGGCGCCCAGGGCGCCGGTTCGGGCT
CGGGGATCATCCTCAGCTCCGACGGCGAGATCCTCACCAACAACCACGTGGTGGAGCTCGCCGGCGACAACGGGTCGATC
CGGGTCTCCTTCAACGACGGCTCCACCGCGAAGGCCGAGATCCTCGGCACCGACCCCCTGACGGACACCGCGGTGATCAA
GGCCCAGGACGTCTCCGGGCTGACGCCCGCGACGATCGGGAAGTCGGGCGACCTCAAGGTCGGCGAGAGCGTCGTGGCGA
TCGGGTCCCCGTTCGGGCTCGACTCGACGGTGACCAGCGGCATCGTGAGTGCGCTGGACCGGCCGGTGGACGTCGGCTCC
GACGGCCAGGGCAACAGCACGACGTACCCCGCGATCCAGACCGACGCTGCGATCAACCCGGGCAACAGCGGCGGCGCGCT
CGTCGACCTCGACGGCAACGTCGTCGGCATCAACTCCTCGATCCGCACCGCCAGCTCCATGGAGGGGCAGGCCGGCTCGA
TCGGGCTCGGCTTCGCCATCCCGATGGACGAGGTGATGCCGATCGTCGACCAGATGGTCAACGGCGAGACCCCGACCCAC
GCCCGCCTCGGCATCTCCGTCTCCGACGTCGCGAGCCGGCCCGGAGCCGAGGTGACCGAGGGCGCCGAGGTCCAAGACGT
CAACGCCGGCTCGACCGCGGACGACGCCGGCCTGGCGAAGGGCGACATCATCACCAAGGTCGACGACCAGCTGATCAGCG
GCGCCGACTCCCTGGTCGCCACCATCAGGTCCTACCGGCCCGGCGACGAGGTCACCGTCACCTACGAGCACGGCGGCGAC
ACCAAGACCGTCACTCTCCAGCTGGACTCGGACGCGGACACGTCCAACTCCTGA

Upstream 100 bases:

>100_bases
CCGCGGTCGCCCGGAATTCCCGGCGGACCGGGGTCGAGTTCTTCGTACCGCCCCAGAAAGGTCTCAGGAAGGTCACAGGC
TGCCCGCCCATGGTTGAGAC

Downstream 100 bases:

>100_bases
TCCGGCCCACAGACCTTTCTCTCCCCCGAGAAGGGATCGGGGCCCCACCGGCCAGCAGGTCCGTCTCCCGTCAGCCGGTG
GGGCCCTCTTCTGCGTCGCC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNDQPTSPPPGPPNPYFSTPAPLGPPPQGPPPGVAPDPQPGQRRPRRTGLAAAVVATALVAGGAAGVGGAAAWSALDDGG
SSSAGGPSSRTTAQVVDTPDSEAPAGSVEQVAAKVLPSVVKIDVAGAQGAGSGSGIILSSDGEILTNNHVVELAGDNGSI
RVSFNDGSTAKAEILGTDPLTDTAVIKAQDVSGLTPATIGKSGDLKVGESVVAIGSPFGLDSTVTSGIVSALDRPVDVGS
DGQGNSTTYPAIQTDAAINPGNSGGALVDLDGNVVGINSSIRTASSMEGQAGSIGLGFAIPMDEVMPIVDQMVNGETPTH
ARLGISVSDVASRPGAEVTEGAEVQDVNAGSTADDAGLAKGDIITKVDDQLISGADSLVATIRSYRPGDEVTVTYEHGGD
TKTVTLQLDSDADTSNS

Sequences:

>Translated_417_residues
MNDQPTSPPPGPPNPYFSTPAPLGPPPQGPPPGVAPDPQPGQRRPRRTGLAAAVVATALVAGGAAGVGGAAAWSALDDGG
SSSAGGPSSRTTAQVVDTPDSEAPAGSVEQVAAKVLPSVVKIDVAGAQGAGSGSGIILSSDGEILTNNHVVELAGDNGSI
RVSFNDGSTAKAEILGTDPLTDTAVIKAQDVSGLTPATIGKSGDLKVGESVVAIGSPFGLDSTVTSGIVSALDRPVDVGS
DGQGNSTTYPAIQTDAAINPGNSGGALVDLDGNVVGINSSIRTASSMEGQAGSIGLGFAIPMDEVMPIVDQMVNGETPTH
ARLGISVSDVASRPGAEVTEGAEVQDVNAGSTADDAGLAKGDIITKVDDQLISGADSLVATIRSYRPGDEVTVTYEHGGD
TKTVTLQLDSDADTSNS
>Mature_417_residues
MNDQPTSPPPGPPNPYFSTPAPLGPPPQGPPPGVAPDPQPGQRRPRRTGLAAAVVATALVAGGAAGVGGAAAWSALDDGG
SSSAGGPSSRTTAQVVDTPDSEAPAGSVEQVAAKVLPSVVKIDVAGAQGAGSGSGIILSSDGEILTNNHVVELAGDNGSI
RVSFNDGSTAKAEILGTDPLTDTAVIKAQDVSGLTPATIGKSGDLKVGESVVAIGSPFGLDSTVTSGIVSALDRPVDVGS
DGQGNSTTYPAIQTDAAINPGNSGGALVDLDGNVVGINSSIRTASSMEGQAGSIGLGFAIPMDEVMPIVDQMVNGETPTH
ARLGISVSDVASRPGAEVTEGAEVQDVNAGSTADDAGLAKGDIITKVDDQLISGADSLVATIRSYRPGDEVTVTYEHGGD
TKTVTLQLDSDADTSNS

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=295, Percent_Identity=34.5762711864407, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI22129776, Length=280, Percent_Identity=36.4285714285714, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI24308541, Length=356, Percent_Identity=32.3033707865169, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7019477, Length=324, Percent_Identity=32.4074074074074, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1786356, Length=283, Percent_Identity=39.9293286219081, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789629, Length=338, Percent_Identity=35.7988165680473, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=33.9285714285714, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646839, Length=267, Percent_Identity=34.8314606741573, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41127; Mature: 41127

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQPTSPPPGPPNPYFSTPAPLGPPPQGPPPGVAPDPQPGQRRPRRTGLAAAVVATALV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGGAAGVGGAAAWSALDDGGSSSAGGPSSRTTAQVVDTPDSEAPAGSVEQVAAKVLPSVV
HCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEE
KIDVAGAQGAGSGSGIILSSDGEILTNNHVVELAGDNGSIRVSFNDGSTAKAEILGTDPL
EEEECCCCCCCCCCEEEEECCCCEEECCEEEEEECCCCEEEEEECCCCCEEEEEEECCCC
TDTAVIKAQDVSGLTPATIGKSGDLKVGESVVAIGSPFGLDSTVTSGIVSALDRPVDVGS
CCCEEEEECCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
DGQGNSTTYPAIQTDAAINPGNSGGALVDLDGNVVGINSSIRTASSMEGQAGSIGLGFAI
CCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCHHCCCCCCCCEEEEEEC
PMDEVMPIVDQMVNGETPTHARLGISVSDVASRPGAEVTEGAEVQDVNAGSTADDAGLAK
CHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
GDIITKVDDQLISGADSLVATIRSYRPGDEVTVTYEHGGDTKTVTLQLDSDADTSNS
CCEEEHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNDQPTSPPPGPPNPYFSTPAPLGPPPQGPPPGVAPDPQPGQRRPRRTGLAAAVVATALV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGGAAGVGGAAAWSALDDGGSSSAGGPSSRTTAQVVDTPDSEAPAGSVEQVAAKVLPSVV
HCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEE
KIDVAGAQGAGSGSGIILSSDGEILTNNHVVELAGDNGSIRVSFNDGSTAKAEILGTDPL
EEEECCCCCCCCCCEEEEECCCCEEECCEEEEEECCCCEEEEEECCCCCEEEEEEECCCC
TDTAVIKAQDVSGLTPATIGKSGDLKVGESVVAIGSPFGLDSTVTSGIVSALDRPVDVGS
CCCEEEEECCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
DGQGNSTTYPAIQTDAAINPGNSGGALVDLDGNVVGINSSIRTASSMEGQAGSIGLGFAI
CCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCHHCCCCCCCCEEEEEEC
PMDEVMPIVDQMVNGETPTHARLGISVSDVASRPGAEVTEGAEVQDVNAGSTADDAGLAK
CHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
GDIITKVDDQLISGADSLVATIRSYRPGDEVTVTYEHGGDTKTVTLQLDSDADTSNS
CCEEEHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]