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The map label for this gene is fur [H]

Identifier: 119715119

GI number: 119715119

Start: 912634

End: 913074

Strand: Direct

Name: fur [H]

Synonym: Noca_0874

Alternate gene names: 119715119

Gene position: 912634-913074 (Clockwise)

Preceding gene: 119715118

Following gene: 119715120

Centisome position: 18.3

GC content: 75.06

Gene sequence:

>441_bases
ATGGCGACGACCACGGACCGCACCCGGGACTTCCCGGAGCTGCTGCGCGGTGCGGCGCTGCGGGTGACCCGCCCGCGGCT
CGCCGTGCTGGGCGCCGTGCACGCGCTGCCGCACGCCGACACCGAGTCGATCATCGGTGCCGTCCGCGAGGGCCTCCCCG
GCGTCTCGCACCAGGCCGTCTACGACTCGCTGCACGCCCTGACCGCCGCCGGCCTGGTACGGCGCATCCAGCCCGCCGGC
TCGGTCGCGCGCTACGAGGCGCGCGTCGGCGACAACCACCACCACGTGGTGTGCCGCGCGTGCGGGATCGTCGCCGACGT
CGACTGCGCCGTCGGCGGCGCGCCCTGCCTGACCGCTTCGGACGACCACGGCTTCCGCATCGACGAGGCCGAGGTCGTCT
ACTGGGGCATCTGCCCCGCCTGCTCGACCACCCGATCGTGA

Upstream 100 bases:

>100_bases
TCGCTCGCGAGGTACCCCTCCCGTGCGGAGCTGCTCGGTGTCGAGGAGACCGTGCCACCCCTTTCTTGACTCATTCCAGA
AAGGTCGCAAGACTGCGGCC

Downstream 100 bases:

>100_bases
CCGCCAACGCCCGTCCGGAAGGAAGACCATGACCGACAGCCAGGACAACCGCACCCCCGAGAGCCCGCAGGGCGTCGACC
GGAAGGCGGAGGGTGGGTGC

Product: ferric-uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MATTTDRTRDFPELLRGAALRVTRPRLAVLGAVHALPHADTESIIGAVREGLPGVSHQAVYDSLHALTAAGLVRRIQPAG
SVARYEARVGDNHHHVVCRACGIVADVDCAVGGAPCLTASDDHGFRIDEAEVVYWGICPACSTTRS

Sequences:

>Translated_146_residues
MATTTDRTRDFPELLRGAALRVTRPRLAVLGAVHALPHADTESIIGAVREGLPGVSHQAVYDSLHALTAAGLVRRIQPAG
SVARYEARVGDNHHHVVCRACGIVADVDCAVGGAPCLTASDDHGFRIDEAEVVYWGICPACSTTRS
>Mature_145_residues
ATTTDRTRDFPELLRGAALRVTRPRLAVLGAVHALPHADTESIIGAVREGLPGVSHQAVYDSLHALTAAGLVRRIQPAGS
VARYEARVGDNHHHVVCRACGIVADVDCAVGGAPCLTASDDHGFRIDEAEVVYWGICPACSTTRS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15434; Mature: 15302

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTDRTRDFPELLRGAALRVTRPRLAVLGAVHALPHADTESIIGAVREGLPGVSHQAV
CCCCCCCCCCHHHHHCCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHH
YDSLHALTAAGLVRRIQPAGSVARYEARVGDNHHHVVCRACGIVADVDCAVGGAPCLTAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHEEHHCCCEECCCCCCCCCEEECC
DDHGFRIDEAEVVYWGICPACSTTRS
CCCCEEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
ATTTDRTRDFPELLRGAALRVTRPRLAVLGAVHALPHADTESIIGAVREGLPGVSHQAV
CCCCCCCCCHHHHHCCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHH
YDSLHALTAAGLVRRIQPAGSVARYEARVGDNHHHVVCRACGIVADVDCAVGGAPCLTAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHEEHHCCCEECCCCCCCCCEEECC
DDHGFRIDEAEVVYWGICPACSTTRS
CCCCEEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]