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The map label for this gene is fur [H]

Identifier: 119715084

GI number: 119715084

Start: 880002

End: 880433

Strand: Reverse

Name: fur [H]

Synonym: Noca_0839

Alternate gene names: 119715084

Gene position: 880433-880002 (Counterclockwise)

Preceding gene: 119715085

Following gene: 119715083

Centisome position: 17.66

GC content: 74.54

Gene sequence:

>432_bases
ATGGCACCTGCCGAGGAGGACCTACGGGCCGCCGGCCTGCGCGTGACCCGCCCGCGGGTCGCCGTACTCGCCGAGGTGTC
CGAGCACCCGCACGCGGACGTCGACACGATCGCGACCGCGGCCCGGGCCCGGCTCGGCAAGGTGTCGACCCAGGCCGTCT
ACGACGTCGTGCACGCGCTCACCGACGCAGGCCTCCTGCGGCGCTTCCAGCCGGCGGGGTCGCCGGCCCGGTTCGAGCTG
GCGACCGGCGACAACCATCACCACCTCGTCTGCCGCGCCTGCCATCGGATCGTCGACGTCGCCTGCGCCACCGGCGAGGC
GCCCTGCCTCCAGGCGAGCGACGACGCCGGCTACCTGCTCGACGAGGCCGAGGTCACCTACTGGGGCCTGTGCGCGAACT
GCCAGGCCGCGGGCGAGCTCGAGCTCCTCTGA

Upstream 100 bases:

>100_bases
GGGCGAGGTCGGAACCTTCCCTTGCGTACGGCAAGTCTTGCGTTAGGCAAGTCTCTGGGCCAAGATGGACTTGATCCGTT
CCAGACCAGGGGGTCAGCGC

Downstream 100 bases:

>100_bases
CCACCGAAGCTCCACCCATCGAGTCGAGAGAGATGAGACCCATGACCACCACGGCACCCGCCCCCACCATCGACGCCTCC
GCCACCGACCCCCGCGCCCG

Product: ferric-uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MAPAEEDLRAAGLRVTRPRVAVLAEVSEHPHADVDTIATAARARLGKVSTQAVYDVVHALTDAGLLRRFQPAGSPARFEL
ATGDNHHHLVCRACHRIVDVACATGEAPCLQASDDAGYLLDEAEVTYWGLCANCQAAGELELL

Sequences:

>Translated_143_residues
MAPAEEDLRAAGLRVTRPRVAVLAEVSEHPHADVDTIATAARARLGKVSTQAVYDVVHALTDAGLLRRFQPAGSPARFEL
ATGDNHHHLVCRACHRIVDVACATGEAPCLQASDDAGYLLDEAEVTYWGLCANCQAAGELELL
>Mature_142_residues
APAEEDLRAAGLRVTRPRVAVLAEVSEHPHADVDTIATAARARLGKVSTQAVYDVVHALTDAGLLRRFQPAGSPARFELA
TGDNHHHLVCRACHRIVDVACATGEAPCLQASDDAGYLLDEAEVTYWGLCANCQAAGELELL

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15225; Mature: 15094

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAEEDLRAAGLRVTRPRVAVLAEVSEHPHADVDTIATAARARLGKVSTQAVYDVVHAL
CCCCHHHHHHCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
TDAGLLRRFQPAGSPARFELATGDNHHHLVCRACHRIVDVACATGEAPCLQASDDAGYLL
HHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEE
DEAEVTYWGLCANCQAAGELELL
CCCCEEEEEEECCCCCCCCEECC
>Mature Secondary Structure 
APAEEDLRAAGLRVTRPRVAVLAEVSEHPHADVDTIATAARARLGKVSTQAVYDVVHAL
CCCHHHHHHCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
TDAGLLRRFQPAGSPARFELATGDNHHHLVCRACHRIVDVACATGEAPCLQASDDAGYLL
HHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEE
DEAEVTYWGLCANCQAAGELELL
CCCCEEEEEEECCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]