BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is ucpA [C]

Identifier: 119715043

GI number: 119715043

Start: 839245

End: 839994

Strand: Reverse

Name: ucpA [C]

Synonym: Noca_0796

Alternate gene names: 119715043

Gene position: 839994-839245 (Counterclockwise)

Preceding gene: 119715056

Following gene: 119715036

Centisome position: 16.85

GC content: 64.67

Gene sequence:

>750_bases
ATGTCGACAGCACGCGCGGCCCTCGTCACCGGCGGCTCCAGCGGGATCGGTCTTGCGATCGCACGTACCCTCGGCGCCGC
TGGGTACGACGTCACGTTGGCCTCCCGACGGCCGGACCGGTTGGAACAAGCGGCCCACGGTCTGCGCGAGGAGGGCTATC
GAGTCGCGACCTCAGCCGGCGATCTCGGCGACGAGGCGGCGGTCGTGGCCGCGGTAGAGACGCACCGCGCCGCGTACGGG
CGCCTTGACGTGCTCGTGAACAACGCGGGCGTGGGGATCGGGCAGTTCGCCGACGACTTGACCACGAAGGCGATCGACAT
ACAGCTCAACACCAATCTACGATCGATCTTCCTCTTCTACCGCGAGGCACTTCCCATGCTGCGGGAGGCGGGTGGCGAAC
ACCGCAACGCCCTGGTCATCAATGTCTCCTCAGCGTCAGGCATCCATGGAGAGCGGTGGCTCGGCGTCTACTCCGCGACC
AAGCGAGGCCTTGTCGGGTTCACGCAGGCAATGAACCGTGAGCTGAACGACGCCGGCATCAAGAGCACAGCGCTTTGCCC
TGCATTCGTGGACACGCCGATGGCAAGCTTCGTCAAGGACGAGATCGGCGCCGACAAGATGATTTCGGTCGACGACGTCG
CTGGATCGGTCCGGTACCTCCTCACACTTTCTCCAGGCTGCCTGATACCCGAGATCCAGTTCGAGCAGACGATCGGCGCA
ATCGGCCCCACCTTCGACCGAACTGGGTAA

Upstream 100 bases:

>100_bases
CGCTCCTGTGCAAGCCTACGGATTCCAGCACCGAGGCTTGCCCCCCCTGCCGAACGATCGTTAGGCTCCGACGCGGAACC
CGACAAGCGAAGGAAGACCG

Downstream 100 bases:

>100_bases
GAGCAATCGCGCCTTGCGACTCGAGCCTTGATCGTGTCGCGGAGCTGCCCACCGCGTCGTATGGGAGATGCCAGCATGTT
GGGGAATGCCGGCACGTGCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSTARAALVTGGSSGIGLAIARTLGAAGYDVTLASRRPDRLEQAAHGLREEGYRVATSAGDLGDEAAVVAAVETHRAAYG
RLDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFYREALPMLREAGGEHRNALVINVSSASGIHGERWLGVYSAT
KRGLVGFTQAMNRELNDAGIKSTALCPAFVDTPMASFVKDEIGADKMISVDDVAGSVRYLLTLSPGCLIPEIQFEQTIGA
IGPTFDRTG

Sequences:

>Translated_249_residues
MSTARAALVTGGSSGIGLAIARTLGAAGYDVTLASRRPDRLEQAAHGLREEGYRVATSAGDLGDEAAVVAAVETHRAAYG
RLDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFYREALPMLREAGGEHRNALVINVSSASGIHGERWLGVYSAT
KRGLVGFTQAMNRELNDAGIKSTALCPAFVDTPMASFVKDEIGADKMISVDDVAGSVRYLLTLSPGCLIPEIQFEQTIGA
IGPTFDRTG
>Mature_248_residues
STARAALVTGGSSGIGLAIARTLGAAGYDVTLASRRPDRLEQAAHGLREEGYRVATSAGDLGDEAAVVAAVETHRAAYGR
LDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFYREALPMLREAGGEHRNALVINVSSASGIHGERWLGVYSATK
RGLVGFTQAMNRELNDAGIKSTALCPAFVDTPMASFVKDEIGADKMISVDDVAGSVRYLLTLSPGCLIPEIQFEQTIGAI
GPTFDRTG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=198, Percent_Identity=32.8282828282828, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=227, Percent_Identity=30.8370044052863, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=33.1658291457286, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI32483357, Length=234, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=232, Percent_Identity=30.6034482758621, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705855, Length=201, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI15277342, Length=234, Percent_Identity=31.1965811965812, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI19923817, Length=240, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI25282469, Length=144, Percent_Identity=32.6388888888889, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI142976729, Length=204, Percent_Identity=27.4509803921569, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=30.1587301587302, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI66933014, Length=115, Percent_Identity=37.3913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=25.2577319587629, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787335, Length=204, Percent_Identity=31.8627450980392, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=227, Percent_Identity=28.6343612334802, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367175, Length=231, Percent_Identity=31.6017316017316, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789057, Length=226, Percent_Identity=28.7610619469027, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789378, Length=193, Percent_Identity=30.5699481865285, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790717, Length=197, Percent_Identity=27.4111675126904, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=210, Percent_Identity=30, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=202, Percent_Identity=31.6831683168317, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=229, Percent_Identity=29.2576419213974, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=29.1457286432161, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=198, Percent_Identity=30.8080808080808, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=30.6532663316583, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=198, Percent_Identity=31.3131313131313, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=25.9067357512953, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=29.4736842105263, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=237, Percent_Identity=28.2700421940928, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=28.4974093264249, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=184, Percent_Identity=30.9782608695652, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=208, Percent_Identity=29.3269230769231, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=25.5102040816327, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=225, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=227, Percent_Identity=25.1101321585903, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=25.7575757575758, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571387, Length=254, Percent_Identity=35.0393700787402, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI116007236, Length=254, Percent_Identity=29.9212598425197, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=35.978835978836, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=26.4462809917355, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641232, Length=237, Percent_Identity=29.1139240506329, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641388, Length=259, Percent_Identity=30.5019305019305, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648944, Length=244, Percent_Identity=28.2786885245902, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=29.8429319371728, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=30.8900523560209, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007234, Length=227, Percent_Identity=30.8370044052863, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=28.4974093264249, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=31.6062176165803, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=31.5533980582524, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=31.5533980582524, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24665247, Length=206, Percent_Identity=31.0679611650485, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=206, Percent_Identity=31.0679611650485, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24663911, Length=256, Percent_Identity=27.34375, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007238, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=25.2525252525253, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356301, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364494, Length=259, Percent_Identity=27.7992277992278, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24656154, Length=207, Percent_Identity=29.4685990338164, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922628, Length=207, Percent_Identity=29.4685990338164, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26227; Mature: 26096

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTARAALVTGGSSGIGLAIARTLGAAGYDVTLASRRPDRLEQAAHGLREEGYRVATSAG
CCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCC
DLGDEAAVVAAVETHRAAYGRLDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFY
CCCCCCEEEEEHHHHHHHHCEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCHHHHHHHH
REALPMLREAGGEHRNALVINVSSASGIHGERWLGVYSATKRGLVGFTQAMNRELNDAGI
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHEEEHHHHHCCCHHHHHHHHCCCCCCCCC
KSTALCPAFVDTPMASFVKDEIGADKMISVDDVAGSVRYLLTLSPGCLIPEIQFEQTIGA
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCEEEEEEECCCCCCCCCHHHHHHHC
IGPTFDRTG
CCCCCCCCC
>Mature Secondary Structure 
STARAALVTGGSSGIGLAIARTLGAAGYDVTLASRRPDRLEQAAHGLREEGYRVATSAG
CCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCC
DLGDEAAVVAAVETHRAAYGRLDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFY
CCCCCCEEEEEHHHHHHHHCEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCHHHHHHHH
REALPMLREAGGEHRNALVINVSSASGIHGERWLGVYSATKRGLVGFTQAMNRELNDAGI
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHEEEHHHHHCCCHHHHHHHHCCCCCCCCC
KSTALCPAFVDTPMASFVKDEIGADKMISVDDVAGSVRYLLTLSPGCLIPEIQFEQTIGA
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCEEEEEEECCCCCCCCCHHHHHHHC
IGPTFDRTG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1508151 [H]