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The map label for this gene is atzB [H]

Identifier: 119714925

GI number: 119714925

Start: 716190

End: 717524

Strand: Reverse

Name: atzB [H]

Synonym: Noca_0677

Alternate gene names: 119714925

Gene position: 717524-716190 (Counterclockwise)

Preceding gene: 119714926

Following gene: 119714923

Centisome position: 14.39

GC content: 73.71

Gene sequence:

>1335_bases
GTGAGGCTCCTGATCCGCGGTGCGGACGCGGTGCTCACGAGCCACCCGGCTGCCGACAGCGTCCTGGTCGAGGACGGCGT
GATCACCGCGATCGGGACCGGCCTGGTCGTCGACGCGGGCACCGGGATCGTCGATGCGCGCGGCGCCGTCGTCGTCCCCG
GGCTCGTCAACACCCACCACCACATGTTCCAGTGCCTGACCCGGGTGCGTGGCCAGGAACACGGTCTGTTCGGCTGGCTC
GGCGAGCTTTGGCCGCTGTTCGGCCGCCACGACAGTGCCTGGCAGGAGGCGGCCACCGCCGTCGCCGCGGGCGAACTGCT
GCTGTCCGGCTGCACCACCACCGTGGACCATCACTACCTGCCTCCGGCATCCGGATCACCCGACCCGGTGGACGCCCAGG
TCACGGCCGGGCGCCGGCTCGGGATCCGGCTGGTCAGCGCCGTCGGCAGCATGGATGTCGACGACGCCCACGGCGGGCTC
GCCCCCGCTGCCCTGTGCGAGTCGACCGACCGCTACCTCCGTCGGTTGGCCGACCTGACCGACCGCCATCACGATCAGGG
GCCGGCATGGCGGACCCGGATCGCGGCCGCCCCCTGCCACCCACTGGCGGTGACCTCGACGCTGGCGCGGGCGGCGCACG
GCTTCGCGCGCGACCGCGAGCTCGGCTTCCACACCCACCTGGCCGAGGCTCGCGACGAGGAAGCGGCGACCGTCAGCGCC
ACCGGCCTCCGCCCGGTCGAGCTGCTGGCGGAGTGGGGCGTCCTCGGCCCGCGTACGTGGCTGGCGCACTGCGTCCATCT
CTCCGACGGCGACATCGAGGTGCTGGCCGACACCGGCACCGCGATCTCGCTCTGCCCCACGTCGAACCTGCGACTGGGCT
CAGGCATCAGCCGGATCCGTGACCTGGTCGACGCGGGCATCACCGTCTCGCTCGGCGTCGACGGGTCAGCGTCCAACGAC
GGCGGCAGTGCCCTGGCCGAGGCGCGCCAGCTGCTGCTGGTCTCCCGGGTGCACGGCGTCGAGCACGGACTCACCGCCTC
CGAGGCACTGGTCGTGGCGACCACCGGAGGCGCCAGGGCACTGGGCCTGCCGGAGCTCGGCAGGATCGAGGTCGGCGCCC
GTGCGGACCTCGCGGTCTTCGACGTCTCCGGGCTCAACGCCGTCGGCACGGAGGCGGACCCGGTGGCCGGCCTGCTGCTC
TCGCCCCCGGCTACCGCCCGACACGTGCTGGTCGAGGGCGAGCTGGTGGTGCGGGACCACGCGCTGGTGAACGCCGACCC
GGCAGAGCTGGCGGCTCGGGCTCGCGAGGTGGCCCGTTCGCTGCAGACCGGCTGA

Upstream 100 bases:

>100_bases
TGGTGCTGCGAGATGGCCGCTGCGTCCACGAGTCTCCGGGCGGGCTGGACCACGCTGACGAGATCTACGCCGCGAGCTAC
CTCACGGGAGCAGGCGTGCC

Downstream 100 bases:

>100_bases
GCTCGACCGGCCCAGAGGCACCTGCCTCATACCCCGCGCATGTCCAGCACCTGGAGGGCCAGGAGGATCCGCAGCCGGAG
CTGAGCGTCGGCGGTGAACG

Product: amidohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRLLIRGADAVLTSHPAADSVLVEDGVITAIGTGLVVDAGTGIVDARGAVVVPGLVNTHHHMFQCLTRVRGQEHGLFGWL
GELWPLFGRHDSAWQEAATAVAAGELLLSGCTTTVDHHYLPPASGSPDPVDAQVTAGRRLGIRLVSAVGSMDVDDAHGGL
APAALCESTDRYLRRLADLTDRHHDQGPAWRTRIAAAPCHPLAVTSTLARAAHGFARDRELGFHTHLAEARDEEAATVSA
TGLRPVELLAEWGVLGPRTWLAHCVHLSDGDIEVLADTGTAISLCPTSNLRLGSGISRIRDLVDAGITVSLGVDGSASND
GGSALAEARQLLLVSRVHGVEHGLTASEALVVATTGGARALGLPELGRIEVGARADLAVFDVSGLNAVGTEADPVAGLLL
SPPATARHVLVEGELVVRDHALVNADPAELAARAREVARSLQTG

Sequences:

>Translated_444_residues
MRLLIRGADAVLTSHPAADSVLVEDGVITAIGTGLVVDAGTGIVDARGAVVVPGLVNTHHHMFQCLTRVRGQEHGLFGWL
GELWPLFGRHDSAWQEAATAVAAGELLLSGCTTTVDHHYLPPASGSPDPVDAQVTAGRRLGIRLVSAVGSMDVDDAHGGL
APAALCESTDRYLRRLADLTDRHHDQGPAWRTRIAAAPCHPLAVTSTLARAAHGFARDRELGFHTHLAEARDEEAATVSA
TGLRPVELLAEWGVLGPRTWLAHCVHLSDGDIEVLADTGTAISLCPTSNLRLGSGISRIRDLVDAGITVSLGVDGSASND
GGSALAEARQLLLVSRVHGVEHGLTASEALVVATTGGARALGLPELGRIEVGARADLAVFDVSGLNAVGTEADPVAGLLL
SPPATARHVLVEGELVVRDHALVNADPAELAARAREVARSLQTG
>Mature_444_residues
MRLLIRGADAVLTSHPAADSVLVEDGVITAIGTGLVVDAGTGIVDARGAVVVPGLVNTHHHMFQCLTRVRGQEHGLFGWL
GELWPLFGRHDSAWQEAATAVAAGELLLSGCTTTVDHHYLPPASGSPDPVDAQVTAGRRLGIRLVSAVGSMDVDDAHGGL
APAALCESTDRYLRRLADLTDRHHDQGPAWRTRIAAAPCHPLAVTSTLARAAHGFARDRELGFHTHLAEARDEEAATVSA
TGLRPVELLAEWGVLGPRTWLAHCVHLSDGDIEVLADTGTAISLCPTSNLRLGSGISRIRDLVDAGITVSLGVDGSASND
GGSALAEARQLLLVSRVHGVEHGLTASEALVVATTGGARALGLPELGRIEVGARADLAVFDVSGLNAVGTEADPVAGLLL
SPPATARHVLVEGELVVRDHALVNADPAELAARAREVARSLQTG

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=337, Percent_Identity=26.1127596439169, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1789249, Length=351, Percent_Identity=29.9145299145299, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6319963, Length=371, Percent_Identity=28.0323450134771, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643849, Length=204, Percent_Identity=30.3921568627451, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 46093; Mature: 46093

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLIRGADAVLTSHPAADSVLVEDGVITAIGTGLVVDAGTGIVDARGAVVVPGLVNTHH
CEEEEECCCHHEECCCCCCCEEECCCEEEEECCCEEEECCCCEEECCCCEEECCHHHHHH
HMFQCLTRVRGQEHGLFGWLGELWPLFGRHDSAWQEAATAVAAGELLLSGCTTTVDHHYL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
PPASGSPDPVDAQVTAGRRLGIRLVSAVGSMDVDDAHGGLAPAALCESTDRYLRRLADLT
CCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DRHHDQGPAWRTRIAAAPCHPLAVTSTLARAAHGFARDRELGFHTHLAEARDEEAATVSA
HHCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEC
TGLRPVELLAEWGVLGPRTWLAHCVHLSDGDIEVLADTGTAISLCPTSNLRLGSGISRIR
CCCCHHHHHHHCCCCCCHHHHHHEEECCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHH
DLVDAGITVSLGVDGSASNDGGSALAEARQLLLVSRVHGVEHGLTASEALVVATTGGARA
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
LGLPELGRIEVGARADLAVFDVSGLNAVGTEADPVAGLLLSPPATARHVLVEGELVVRDH
CCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEEECEEEEECC
ALVNADPAELAARAREVARSLQTG
EEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLLIRGADAVLTSHPAADSVLVEDGVITAIGTGLVVDAGTGIVDARGAVVVPGLVNTHH
CEEEEECCCHHEECCCCCCCEEECCCEEEEECCCEEEECCCCEEECCCCEEECCHHHHHH
HMFQCLTRVRGQEHGLFGWLGELWPLFGRHDSAWQEAATAVAAGELLLSGCTTTVDHHYL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
PPASGSPDPVDAQVTAGRRLGIRLVSAVGSMDVDDAHGGLAPAALCESTDRYLRRLADLT
CCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DRHHDQGPAWRTRIAAAPCHPLAVTSTLARAAHGFARDRELGFHTHLAEARDEEAATVSA
HHCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEC
TGLRPVELLAEWGVLGPRTWLAHCVHLSDGDIEVLADTGTAISLCPTSNLRLGSGISRIR
CCCCHHHHHHHCCCCCCHHHHHHEEECCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHH
DLVDAGITVSLGVDGSASNDGGSALAEARQLLLVSRVHGVEHGLTASEALVVATTGGARA
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
LGLPELGRIEVGARADLAVFDVSGLNAVGTEADPVAGLLLSPPATARHVLVEGELVVRDH
CCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEEECEEEEECC
ALVNADPAELAARAREVARSLQTG
EEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]