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The map label for this gene is 119714903

Identifier: 119714903

GI number: 119714903

Start: 694654

End: 695829

Strand: Reverse

Name: 119714903

Synonym: Noca_0655

Alternate gene names: NA

Gene position: 695829-694654 (Counterclockwise)

Preceding gene: 119714904

Following gene: 119714901

Centisome position: 13.96

GC content: 73.89

Gene sequence:

>1176_bases
GTGAGGACCTGGGTCCCCGGCGCGGCCGGCTCCGGGTTCGACGTCGACCACCTGCCGTACGGCGTGTTCTCCCGCGCCGG
GGAGGAGCCGCGGGTCGGCGTCCGCATCGGCGACCAGGTGCTCGACCTGGCACCGGTCGCCGCCGCCGAGATGCTCGACG
TCCACCGCGTCCTCGAGGAGCGCTCGCTGAACGCGCTGATGGCGGAAGGGCGCCGGGTCCGCGAGTCGGTGCGCGCCTGG
GTCACCGGGCTGCTCAGCGACGAGGCCGAGCGCGACCTGGTCGAGCCGCACCTGGTCCCGCTCGCAGAGGTCGCCCTGCA
CCTGCCGGTCGAGGTGGCCGACTACGTCGACTTCTACGCGAGCGAGCACCACGCCTCCAACGTCGGCCGGATCTTCCGCC
CCGACGCCGAGCCCTTGCTGCCGAACTGGAAGCACCTGCCGGTCGGCTACCACGGTCGCGCCGGCACGGTGGTCGCGTCC
GGCACCCCCGTCGTCCGCCCGTGCGGGCAGCGGCGCGGCGACGCAGGCCCGACGTACGGCCCCTCGACACGGCTCGACAT
CGAGGCCGAGCTCGGCTTCGTGGTCGGCACGCCGTCCGAGCTCGGGACTCCGGTGCGGTACGACGCGTTCGCCGACCACG
TGTTCGGCGTGGTCGGCCTCAACGACTGGTCGGCGCGCGACATCCAGGCCTGGGAGTACGTACCCCTGGGGCCGTTCCTC
GGCAAGTCCTTCGCGACCTCGGTGTCCCAGTGGGTGACGCCGCTCGAGGCGCTCGACGCGGCGTGGGTCGACCTGCCCGG
CCAGGACCCGGAGCCGTTGCCCTACCTGGGCCCCGGCGCCACCCGGGGGCTCGACATCGACGTCGAGGTGGTCGTCAACG
GCGAGGTCGTCAGCCGGCCGCCCTACCGCACGATGTACTGGTCGCCGGCGCAGCTGCTCGCCCATCTCACGGTGAACGGA
GCGAGCCTGCGCACCGGCGACCTCTACGCGTCGGGCACCATCAGCGGCCCGGAGCCGGACCAGCGCGGCTCACTGCTGGA
GCTGGGCTGGGGCGCCGACGACGCGTTCCTCGACGACGGCGACGAGGTCGTGCTCCGCTACGCCGCACCCGGCACGTCCG
GCGGCCGGATCACGCTCGGTGAGGTGGCCGGGGTCATCGCGCCCGCACGCACCTGA

Upstream 100 bases:

>100_bases
TCGACCTCGCGGGTGCCCGGCGCTGGTTCACCTCCTTCGGGTCGTGCTCGATCGACGAGCCGTTCGAGGACCTGGTCGCG
CTCGGCCTGCTGGAGCTCTC

Downstream 100 bases:

>100_bases
GCGGGCTCCGGCTCCACCGCCACCCCCGCGACCGACCCCGCAGCGGGGATCCACTCCGCCGACACGATCCGCTCGATCCG
GGCTCGTGAGCGGCGGGTCA

Product: fumarylacetoacetate hydrolase

Products: acetoacetate; fumarate

Alternate protein names: Fumarylacetoacetate Hydrolase; Fumarylacetoacetase Hydrolase; Hydroxylase; LOW QUALITY PROTEIN Fumarylacetoacetase

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRTWVPGAAGSGFDVDHLPYGVFSRAGEEPRVGVRIGDQVLDLAPVAAAEMLDVHRVLEERSLNALMAEGRRVRESVRAW
VTGLLSDEAERDLVEPHLVPLAEVALHLPVEVADYVDFYASEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVAS
GTPVVRPCGQRRGDAGPTYGPSTRLDIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWSARDIQAWEYVPLGPFL
GKSFATSVSQWVTPLEALDAAWVDLPGQDPEPLPYLGPGATRGLDIDVEVVVNGEVVSRPPYRTMYWSPAQLLAHLTVNG
ASLRTGDLYASGTISGPEPDQRGSLLELGWGADDAFLDDGDEVVLRYAAPGTSGGRITLGEVAGVIAPART

Sequences:

>Translated_391_residues
MRTWVPGAAGSGFDVDHLPYGVFSRAGEEPRVGVRIGDQVLDLAPVAAAEMLDVHRVLEERSLNALMAEGRRVRESVRAW
VTGLLSDEAERDLVEPHLVPLAEVALHLPVEVADYVDFYASEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVAS
GTPVVRPCGQRRGDAGPTYGPSTRLDIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWSARDIQAWEYVPLGPFL
GKSFATSVSQWVTPLEALDAAWVDLPGQDPEPLPYLGPGATRGLDIDVEVVVNGEVVSRPPYRTMYWSPAQLLAHLTVNG
ASLRTGDLYASGTISGPEPDQRGSLLELGWGADDAFLDDGDEVVLRYAAPGTSGGRITLGEVAGVIAPART
>Mature_391_residues
MRTWVPGAAGSGFDVDHLPYGVFSRAGEEPRVGVRIGDQVLDLAPVAAAEMLDVHRVLEERSLNALMAEGRRVRESVRAW
VTGLLSDEAERDLVEPHLVPLAEVALHLPVEVADYVDFYASEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVAS
GTPVVRPCGQRRGDAGPTYGPSTRLDIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWSARDIQAWEYVPLGPFL
GKSFATSVSQWVTPLEALDAAWVDLPGQDPEPLPYLGPGATRGLDIDVEVVVNGEVVSRPPYRTMYWSPAQLLAHLTVNG
ASLRTGDLYASGTISGPEPDQRGSLLELGWGADDAFLDDGDEVVLRYAAPGTSGGRITLGEVAGVIAPART

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557587, Length=415, Percent_Identity=45.3012048192771, Blast_Score=344, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI17568863, Length=417, Percent_Identity=46.7625899280576, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI24657182, Length=412, Percent_Identity=43.6893203883495, Blast_Score=324, Evalue=7e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.7.1.2

Molecular weight: Translated: 41930; Mature: 41930

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTWVPGAAGSGFDVDHLPYGVFSRAGEEPRVGVRIGDQVLDLAPVAAAEMLDVHRVLEE
CCCCCCCCCCCCCCHHCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RSLNALMAEGRRVRESVRAWVTGLLSDEAERDLVEPHLVPLAEVALHLPVEVADYVDFYA
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
SEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVASGTPVVRPCGQRRGDAGPTYG
HHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PSTRLDIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWSARDIQAWEYVPLGPFL
CCCEEEEEEECEEEEECHHHHCCCEEHHHHHHHHEEEEECCCCCCCCCCCEEEEECCHHH
GKSFATSVSQWVTPLEALDAAWVDLPGQDPEPLPYLGPGATRGLDIDVEVVVNGEVVSRP
HHHHHHHHHHHHCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCC
PYRTMYWSPAQLLAHLTVNGASLRTGDLYASGTISGPEPDQRGSLLELGWGADDAFLDDG
CCCEEEECHHHHHHHHEECCCEEECCCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DEVVLRYAAPGTSGGRITLGEVAGVIAPART
CEEEEEEECCCCCCCEEEHHHHHHHHCCCCC
>Mature Secondary Structure
MRTWVPGAAGSGFDVDHLPYGVFSRAGEEPRVGVRIGDQVLDLAPVAAAEMLDVHRVLEE
CCCCCCCCCCCCCCHHCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RSLNALMAEGRRVRESVRAWVTGLLSDEAERDLVEPHLVPLAEVALHLPVEVADYVDFYA
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
SEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVASGTPVVRPCGQRRGDAGPTYG
HHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PSTRLDIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWSARDIQAWEYVPLGPFL
CCCEEEEEEECEEEEECHHHHCCCEEHHHHHHHHEEEEECCCCCCCCCCCEEEEECCHHH
GKSFATSVSQWVTPLEALDAAWVDLPGQDPEPLPYLGPGATRGLDIDVEVVVNGEVVSRP
HHHHHHHHHHHHCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCC
PYRTMYWSPAQLLAHLTVNGASLRTGDLYASGTISGPEPDQRGSLLELGWGADDAFLDDG
CCCEEEECHHHHHHHHEECCCEEECCCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DEVVLRYAAPGTSGGRITLGEVAGVIAPART
CEEEEEEECCCCCCCEEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-fumarylacetoacetate; H2O

Specific reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA