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The map label for this gene is tmd [H]

Identifier: 119714841

GI number: 119714841

Start: 611044

End: 613143

Strand: Reverse

Name: tmd [H]

Synonym: Noca_0579

Alternate gene names: 119714841

Gene position: 613143-611044 (Counterclockwise)

Preceding gene: 119714844

Following gene: 119714838

Centisome position: 12.3

GC content: 63.24

Gene sequence:

>2100_bases
TTGAATCGCGTGCCCCCGGCTGCTCATCACAGGGTCCTATTCGAACCCATCTCAATCGGCTCGAAGACCCTTCGAAACCG
CTTCTTCAACGTGGCCCACGGCACCGCCTACGGGGTACTTCGTCCGTCCACGTGGGCCTCATACCGCGCTGTTCGCGCTG
AAGGCGGCTGGGCAGCGGTGTCGACAGAGTTCTCCAGCGTGGGGCCCAGCAGCGACGAGTCCCCCCTGCACTCCAGTGAC
ATCTGGGACGGGGAAGACGGACGACGGCACAAAGCTATGGTCGACGCCGTCCATGAACACGGTGCGCTCGCGAGCATCGA
ACTGCATCATGGCGGCGCTCACGCTATGCGAAGGCTGTCCCGAGAGCCTGCGCTGTCGCCGTCCGGCCTCGCCGGCGAAT
TGCCACCGCCCGCCGGACCACTTGGGACTCCGAAAGTCATGACCCTCGAGGACATTGAGCGCGTCGAGCAGTCCTTTGTT
GACGCGGCGGTGCGTGCACGCGACGTGGGCTACGACATCGTGGACGTGCTCGCGGGATATGGATATCTCTTCGCGCAGTT
CCTGTCCGCATTCCACAACCACCGCACCGACAAGTATGGCGGGTCGTTGGAGAACAGGGCCAGGTTCTGGATCGAGACCC
TCGGCCGAGTCCGTGACGCCGTAGGTGCCGACTGCGCGGTCGCGAGTCGCATGTCGATCCAGACGCAGGGTCCGTGGGGT
CACACGCTGGACGAGAGCGTGGAGTTGGTCCGGATGGCTGATCCACTGGTCGACTTGTGGGATCTCAATGTTGGGTCCGT
CCTGGATTGGGGTAGCGACATCAGCCCGTCGAGGGTCATCCCCGAGGGGCACAACGTAGAGCTCTTCACACGCGTTCGGA
GCGCCACTCAGAAGCCCATCGTCGGGGTATCGCGATGGACGAGTCCTGACCTGATGGCCGAGGTAGTGCGCTCTGGAGTT
ATCGACCTCATCGGATCTGCTCGCCAGTCGATCGCGGATCCCTTCTTCCCCCAGAAGGTCTATGAGGGTCGCATCGAGGA
CATCAGGGAATGCATGGGTATCAATCACTGCATCAGTAGTCTCGATCGGGGCAACATGGCGTGTGCTCAGAACGCCACCG
CCGGCGAGGAGTACAGGCGTGGCTGGCACCCGGAGCGCTTCGAACCTCTCGAACGCCCAGACGTCAGCGTCTTGGTCGTC
GGCGCAGGCCCGGCAGGTTTGGAAGCAGCAATCGGCCTGGCGAGGCGAGGTGCCGACATGGTGCACCTCGTCGACTCTGC
CGACCAGGTTGGCGGCCACCTCCGTCAAGTAGTCGACCTACCGGGACTTCGAGAGTGGGGACGCTTCATCGATCACCGTA
AGATCCAGATCGACAAGCTGCCGAACTTGCAGCTCATCGCCTCGACCACCTTAAGCGCCGCCGAGATCCTCGAATACGGG
GCATCCCACGTAGTTGTCGCGACGGGCGCACGATGGTTGGACACCGGGCTCGCGCCAGGCACACACACGCCGCTGCCAGG
AGTCGACGGCCTGGAATGGGTGTTCACGCCTGACCAGTTGCTCGCCCGCGGCGACCGACCCGTCTCGGGTTGTCGCGTGA
CCGTCTACGACGCTGAGGGCAGTTATATGGGGTCGGGTCTCTCTCAACTCCTTGCCGACGAAGGCTACAAAGTCTCCGTC
GTGACGCCGCACGCTCAGGTGACAGCGGAAGGGGACCTGACGCTGGACGGGCCGGCGGTTCGTAGGTCTCTTCACACCAG
CGGGGTCGCCATGTACCGGAACGTGTCATTGACGGAGGTCGGCGACGGGCTGCTCCGAGGGGCGGATGAATTCGAGGAGC
CGTTCTTACTTGAGACGGACGCTCTCGTGCTCGTGACGATGCGGGCACCAGTCGACGACGTGTATCGCCAACTCGTCAGC
GAACGCAACACGCTTCACGAGTCGGAAATCGAGGCCGTTCTTTGCATCGGAGATGCGCAGTCTCCGCGCCCGCTGGCCGA
GGCGATGTTCGATGGTCATCGCTTGGCACGTGAGTTCGAGTCAACCGATCCCTCGGTGCCGCTGCCGTACAGGCGCGAGT
CGTTGCAGTTCGTCAAGTGA

Upstream 100 bases:

>100_bases
TATGTATCGCTCAGCCCGGCGACGTCACACCTCTCACTGACATCCCCACGTACTAGAAGACGCCCCCGGCGCTCTCACAC
CCCTGCCACCCGACGAAAGG

Downstream 100 bases:

>100_bases
GGTCACGGCGGCGTGCGCTTGTTCGTGCGTGACCAAGGGAGGTTGATTCCTACCCCCCTCCCCCCACATGCATTGGCTAC
TGTCCGCGGCGTCAAGAGAT

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: TMADh [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MNRVPPAAHHRVLFEPISIGSKTLRNRFFNVAHGTAYGVLRPSTWASYRAVRAEGGWAAVSTEFSSVGPSSDESPLHSSD
IWDGEDGRRHKAMVDAVHEHGALASIELHHGGAHAMRRLSREPALSPSGLAGELPPPAGPLGTPKVMTLEDIERVEQSFV
DAAVRARDVGYDIVDVLAGYGYLFAQFLSAFHNHRTDKYGGSLENRARFWIETLGRVRDAVGADCAVASRMSIQTQGPWG
HTLDESVELVRMADPLVDLWDLNVGSVLDWGSDISPSRVIPEGHNVELFTRVRSATQKPIVGVSRWTSPDLMAEVVRSGV
IDLIGSARQSIADPFFPQKVYEGRIEDIRECMGINHCISSLDRGNMACAQNATAGEEYRRGWHPERFEPLERPDVSVLVV
GAGPAGLEAAIGLARRGADMVHLVDSADQVGGHLRQVVDLPGLREWGRFIDHRKIQIDKLPNLQLIASTTLSAAEILEYG
ASHVVVATGARWLDTGLAPGTHTPLPGVDGLEWVFTPDQLLARGDRPVSGCRVTVYDAEGSYMGSGLSQLLADEGYKVSV
VTPHAQVTAEGDLTLDGPAVRRSLHTSGVAMYRNVSLTEVGDGLLRGADEFEEPFLLETDALVLVTMRAPVDDVYRQLVS
ERNTLHESEIEAVLCIGDAQSPRPLAEAMFDGHRLAREFESTDPSVPLPYRRESLQFVK

Sequences:

>Translated_699_residues
MNRVPPAAHHRVLFEPISIGSKTLRNRFFNVAHGTAYGVLRPSTWASYRAVRAEGGWAAVSTEFSSVGPSSDESPLHSSD
IWDGEDGRRHKAMVDAVHEHGALASIELHHGGAHAMRRLSREPALSPSGLAGELPPPAGPLGTPKVMTLEDIERVEQSFV
DAAVRARDVGYDIVDVLAGYGYLFAQFLSAFHNHRTDKYGGSLENRARFWIETLGRVRDAVGADCAVASRMSIQTQGPWG
HTLDESVELVRMADPLVDLWDLNVGSVLDWGSDISPSRVIPEGHNVELFTRVRSATQKPIVGVSRWTSPDLMAEVVRSGV
IDLIGSARQSIADPFFPQKVYEGRIEDIRECMGINHCISSLDRGNMACAQNATAGEEYRRGWHPERFEPLERPDVSVLVV
GAGPAGLEAAIGLARRGADMVHLVDSADQVGGHLRQVVDLPGLREWGRFIDHRKIQIDKLPNLQLIASTTLSAAEILEYG
ASHVVVATGARWLDTGLAPGTHTPLPGVDGLEWVFTPDQLLARGDRPVSGCRVTVYDAEGSYMGSGLSQLLADEGYKVSV
VTPHAQVTAEGDLTLDGPAVRRSLHTSGVAMYRNVSLTEVGDGLLRGADEFEEPFLLETDALVLVTMRAPVDDVYRQLVS
ERNTLHESEIEAVLCIGDAQSPRPLAEAMFDGHRLAREFESTDPSVPLPYRRESLQFVK
>Mature_699_residues
MNRVPPAAHHRVLFEPISIGSKTLRNRFFNVAHGTAYGVLRPSTWASYRAVRAEGGWAAVSTEFSSVGPSSDESPLHSSD
IWDGEDGRRHKAMVDAVHEHGALASIELHHGGAHAMRRLSREPALSPSGLAGELPPPAGPLGTPKVMTLEDIERVEQSFV
DAAVRARDVGYDIVDVLAGYGYLFAQFLSAFHNHRTDKYGGSLENRARFWIETLGRVRDAVGADCAVASRMSIQTQGPWG
HTLDESVELVRMADPLVDLWDLNVGSVLDWGSDISPSRVIPEGHNVELFTRVRSATQKPIVGVSRWTSPDLMAEVVRSGV
IDLIGSARQSIADPFFPQKVYEGRIEDIRECMGINHCISSLDRGNMACAQNATAGEEYRRGWHPERFEPLERPDVSVLVV
GAGPAGLEAAIGLARRGADMVHLVDSADQVGGHLRQVVDLPGLREWGRFIDHRKIQIDKLPNLQLIASTTLSAAEILEYG
ASHVVVATGARWLDTGLAPGTHTPLPGVDGLEWVFTPDQLLARGDRPVSGCRVTVYDAEGSYMGSGLSQLLADEGYKVSV
VTPHAQVTAEGDLTLDGPAVRRSLHTSGVAMYRNVSLTEVGDGLLRGADEFEEPFLLETDALVLVTMRAPVDDVYRQLVS
ERNTLHESEIEAVLCIGDAQSPRPLAEAMFDGHRLAREFESTDPSVPLPYRRESLQFVK

Specific function: Catalyzes The NADP-Dependent Reduction Of 2,4-Dienoyl- CoA To Yield Trans-2- Enoyl-CoA. [C]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=546, Percent_Identity=26.7399267399267, Blast_Score=149, Evalue=8e-37,
Organism=Escherichia coli, GI1787939, Length=350, Percent_Identity=26.8571428571429, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=404, Percent_Identity=25.7425742574257, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=334, Percent_Identity=27.2455089820359, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=256, Percent_Identity=29.6875, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=300, Percent_Identity=25, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=257, Percent_Identity=27.6264591439689, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=307, Percent_Identity=27.3615635179153, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=262, Percent_Identity=25.9541984732824, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=243, Percent_Identity=30.4526748971193, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=28.1938325991189, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.5.8.2 [H]

Molecular weight: Translated: 76208; Mature: 76208

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVPPAAHHRVLFEPISIGSKTLRNRFFNVAHGTAYGVLRPSTWASYRAVRAEGGWAAV
CCCCCCCHHCEEEEEHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHEEECCCCEEEE
STEFSSVGPSSDESPLHSSDIWDGEDGRRHKAMVDAVHEHGALASIELHHGGAHAMRRLS
ECCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
REPALSPSGLAGELPPPAGPLGTPKVMTLEDIERVEQSFVDAAVRARDVGYDIVDVLAGY
CCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GYLFAQFLSAFHNHRTDKYGGSLENRARFWIETLGRVRDAVGADCAVASRMSIQTQGPWG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEEEECCCCC
HTLDESVELVRMADPLVDLWDLNVGSVLDWGSDISPSRVIPEGHNVELFTRVRSATQKPI
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
VGVSRWTSPDLMAEVVRSGVIDLIGSARQSIADPFFPQKVYEGRIEDIRECMGINHCISS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCHHHHHHH
LDRGNMACAQNATAGEEYRRGWHPERFEPLERPDVSVLVVGAGPAGLEAAIGLARRGADM
CCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCE
VHLVDSADQVGGHLRQVVDLPGLREWGRFIDHRKIQIDKLPNLQLIASTTLSAAEILEYG
EEEHHCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHCC
ASHVVVATGARWLDTGLAPGTHTPLPGVDGLEWVFTPDQLLARGDRPVSGCRVTVYDAEG
CCEEEEECCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEEEEEECCC
SYMGSGLSQLLADEGYKVSVVTPHAQVTAEGDLTLDGPAVRRSLHTSGVAMYRNVSLTEV
CHHHHHHHHHHHCCCCEEEEECCCCEEEECCCEEECCHHHHHHHHHCCCHHEECCCHHHH
GDGLLRGADEFEEPFLLETDALVLVTMRAPVDDVYRQLVSERNTLHESEIEAVLCIGDAQ
CCHHHCCCHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCCEEEEECCCC
SPRPLAEAMFDGHRLAREFESTDPSVPLPYRRESLQFVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNRVPPAAHHRVLFEPISIGSKTLRNRFFNVAHGTAYGVLRPSTWASYRAVRAEGGWAAV
CCCCCCCHHCEEEEEHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHEEECCCCEEEE
STEFSSVGPSSDESPLHSSDIWDGEDGRRHKAMVDAVHEHGALASIELHHGGAHAMRRLS
ECCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
REPALSPSGLAGELPPPAGPLGTPKVMTLEDIERVEQSFVDAAVRARDVGYDIVDVLAGY
CCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GYLFAQFLSAFHNHRTDKYGGSLENRARFWIETLGRVRDAVGADCAVASRMSIQTQGPWG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEEEECCCCC
HTLDESVELVRMADPLVDLWDLNVGSVLDWGSDISPSRVIPEGHNVELFTRVRSATQKPI
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
VGVSRWTSPDLMAEVVRSGVIDLIGSARQSIADPFFPQKVYEGRIEDIRECMGINHCISS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCHHHHHHH
LDRGNMACAQNATAGEEYRRGWHPERFEPLERPDVSVLVVGAGPAGLEAAIGLARRGADM
CCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCE
VHLVDSADQVGGHLRQVVDLPGLREWGRFIDHRKIQIDKLPNLQLIASTTLSAAEILEYG
EEEHHCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHCC
ASHVVVATGARWLDTGLAPGTHTPLPGVDGLEWVFTPDQLLARGDRPVSGCRVTVYDAEG
CCEEEEECCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEEEEEECCC
SYMGSGLSQLLADEGYKVSVVTPHAQVTAEGDLTLDGPAVRRSLHTSGVAMYRNVSLTEV
CHHHHHHHHHHHCCCCEEEEECCCCEEEECCCEEECCHHHHHHHHHCCCHHEECCCHHHH
GDGLLRGADEFEEPFLLETDALVLVTMRAPVDDVYRQLVSERNTLHESEIEAVLCIGDAQ
CCHHHCCCHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCCEEEEECCCC
SPRPLAEAMFDGHRLAREFESTDPSVPLPYRRESLQFVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1505666; 620783; 1551870; 12567183 [H]