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The map label for this gene is atpA

Identifier: 119386523

GI number: 119386523

Start: 955419

End: 956954

Strand: Direct

Name: atpA

Synonym: Pden_3816

Alternate gene names: 119386523

Gene position: 955419-956954 (Clockwise)

Preceding gene: 119386522

Following gene: 119386524

Centisome position: 55.22

GC content: 65.1

Gene sequence:

>1536_bases
ATGGGAATCCAGGCAGCCGAAATCTCGGCCATCCTCAAGGATCAGATCAAGAATTTCGGTCAGGACGCCGAGGTGGCCGA
GGTCGGGCAGGTGCTGTCCGTCGGTGACGGCATCGCCCGCGTCTATGGCCTGGACAAGGTTCAGGCCGGCGAGATGGTCG
AATTCCCGGGCGGCATCCGCGGCATGGTGCTGAACCTTGAAACCGACAACGTCGGCGTCGTGATCTTCGGCGACGACCGC
GACATCAAGGAAGGCGACACCGTCAAGCGCACCGGCGCCATCGTGGAAGTCCCCGCCGGCAAGGAACTGCTGGGCCGCGT
CGTCGACGCGCTTGGCAACCCGATCGACGGCAAGGGCCCGCTGAACGCCTCCGAGCGCCGCATCGCCGACGTCAAGGCCC
CCGGCATCATGCCGCGCAAATCGGTGCACGAGCCGATGGCGACCGGCCTGAAATCGGTGGACGCCATGATCCCGGTCGGC
CGCGGCCAGCGCGAGCTGATCATCGGCGACCGCCAGACCGGCAAGACCGCCATCGCGCTGGACACCATCCTGAACCAGGC
GAACTACAACGGCCGCGAGGCCGATGGCATGAAGACCCTGCACTGCATCTATGTCGCCGTCGGCCAGAAGCGCTCGACCG
TGGCCCAGCTGGTGAAGAAGCTGGAAGAGACCGGCGCCATGGCCTACACGACCGTCGTGGCCGCGACCGCCTCGGACCCG
GCGCCGATGCAGTATCTGGCGCCCTATTCGGCCACCGCGATGGGCGAATATTTCCGCGACAACGGCATGGATGCGCTGAT
CATCTATGACGACCTGTCGAAACAGGCCGTGGCCTATCGCCAGATGTCGCTGCTGCTGCGCCGCCCGCCGGGGCGCGAAG
CCTATCCGGGCGACGTGTTCTACCTGCATTCGCGCCTGCTGGAGCGTTCGGCCAAGCTGAACGAGGCCAATGGCGCCGGC
TCGCTGACCGCGCTGCCGATCATCGAGACGCAGGCGGGCGACGTGTCGGCCTACATCCCGACCAACGTGATCTCGATCAC
CGACGGCCAGATCTTCCTGGAAACCGAACTGTTCTTCCAGGGCATCCGCCCTGCCGTGAACACCGGCCTTTCGGTGTCGC
GCGTGGGTTCCGCGGCGCAGACCAAGGCGATGAAATCCGTCGCCGGCCCGGTCAAGCTGGAACTGGCCCAGTATCGCGAG
ATGGCGGCCTTCGCGCAGTTCGGCTCGGACCTCGACGCCGCGACGCAGAAACTGCTGAACCGCGGTGCGCGCCTGACCGA
GTTGATGAAGCAGCCGCAATACTCGCCGCTGACCAATGCCGAGATCGTCATCGTCATCTATGCCGGCACCAAGGGCTACC
TGGACGGCATCCCGGTTCGCGACGTGACCAAATGGGAGCATGGGCTGCTCCAGTATCTGCGCAACCAGAAGGCCGATCTG
CTTGAGGACATGACCAAGAACGACCGCAAGGTGGCGGGCGAGCTTGAAGATGCGATCAAGGCAGCGCTGGACGGTTACGC
CAAGACCTACGCCTGA

Upstream 100 bases:

>100_bases
TCATCGGCGGCATGATCGTCAAACTGGGCTCGCAGATGATCGACAGTTCGATCCGCTCGAAGCTCGCCTCCCTCCAGAAT
GCTATGAAAGAGGTCGGATA

Downstream 100 bases:

>100_bases
GGGGAGGGATAGATGCCCAGCCTCAAGGACCTCAAGAACCGGATCGGCAGCGTCAAGAACACGCGCAAGATCACCAAGGC
GATGCAGATGGTCGCCGCCG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MGIQAAEISAILKDQIKNFGQDAEVAEVGQVLSVGDGIARVYGLDKVQAGEMVEFPGGIRGMVLNLETDNVGVVIFGDDR
DIKEGDTVKRTGAIVEVPAGKELLGRVVDALGNPIDGKGPLNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVG
RGQRELIIGDRQTGKTAIALDTILNQANYNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEETGAMAYTTVVAATASDP
APMQYLAPYSATAMGEYFRDNGMDALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEANGAG
SLTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSAAQTKAMKSVAGPVKLELAQYRE
MAAFAQFGSDLDAATQKLLNRGARLTELMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVRDVTKWEHGLLQYLRNQKADL
LEDMTKNDRKVAGELEDAIKAALDGYAKTYA

Sequences:

>Translated_511_residues
MGIQAAEISAILKDQIKNFGQDAEVAEVGQVLSVGDGIARVYGLDKVQAGEMVEFPGGIRGMVLNLETDNVGVVIFGDDR
DIKEGDTVKRTGAIVEVPAGKELLGRVVDALGNPIDGKGPLNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVG
RGQRELIIGDRQTGKTAIALDTILNQANYNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEETGAMAYTTVVAATASDP
APMQYLAPYSATAMGEYFRDNGMDALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEANGAG
SLTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSAAQTKAMKSVAGPVKLELAQYRE
MAAFAQFGSDLDAATQKLLNRGARLTELMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVRDVTKWEHGLLQYLRNQKADL
LEDMTKNDRKVAGELEDAIKAALDGYAKTYA
>Mature_510_residues
GIQAAEISAILKDQIKNFGQDAEVAEVGQVLSVGDGIARVYGLDKVQAGEMVEFPGGIRGMVLNLETDNVGVVIFGDDRD
IKEGDTVKRTGAIVEVPAGKELLGRVVDALGNPIDGKGPLNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVGR
GQRELIIGDRQTGKTAIALDTILNQANYNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEETGAMAYTTVVAATASDPA
PMQYLAPYSATAMGEYFRDNGMDALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEANGAGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSAAQTKAMKSVAGPVKLELAQYREM
AAFAQFGSDLDAATQKLLNRGARLTELMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVRDVTKWEHGLLQYLRNQKADLL
EDMTKNDRKVAGELEDAIKAALDGYAKTYA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=476, Percent_Identity=72.0588235294118, Blast_Score=701, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=476, Percent_Identity=72.0588235294118, Blast_Score=701, Evalue=0.0,
Organism=Homo sapiens, GI19913426, Length=357, Percent_Identity=28.2913165266106, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913428, Length=340, Percent_Identity=27.3529411764706, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI32189394, Length=428, Percent_Identity=25, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI19913424, Length=320, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790172, Length=524, Percent_Identity=55.9160305343511, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1790170, Length=447, Percent_Identity=23.7136465324385, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788251, Length=288, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=509, Percent_Identity=67.3870333988212, Blast_Score=695, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=509, Percent_Identity=67.3870333988212, Blast_Score=694, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=509, Percent_Identity=62.278978388998, Blast_Score=627, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17510931, Length=304, Percent_Identity=27.6315789473684, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=346, Percent_Identity=25.7225433526012, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988068, Length=79, Percent_Identity=54.4303797468354, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=315, Percent_Identity=25.3968253968254, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=68, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=265, Percent_Identity=25.6603773584906, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=65.6804733727811, Blast_Score=690, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=342, Percent_Identity=29.5321637426901, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=357, Percent_Identity=26.3305322128852, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658560, Length=484, Percent_Identity=70.0413223140496, Blast_Score=700, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=338, Percent_Identity=27.810650887574, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646341, Length=338, Percent_Identity=27.810650887574, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136796, Length=338, Percent_Identity=27.810650887574, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24638766, Length=298, Percent_Identity=25.503355704698, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574560, Length=411, Percent_Identity=24.0875912408759, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583992, Length=320, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583988, Length=249, Percent_Identity=25.7028112449799, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583986, Length=249, Percent_Identity=25.7028112449799, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583984, Length=249, Percent_Identity=25.7028112449799, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PARDP (A1B8N8)

Other databases:

- EMBL:   CP000490
- RefSeq:   YP_917578.1
- ProteinModelPortal:   A1B8N8
- SMR:   A1B8N8
- STRING:   A1B8N8
- GeneID:   4582367
- GenomeReviews:   CP000490_GR
- KEGG:   pde:Pden_3816
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- PhylomeDB:   A1B8N8
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55040; Mature: 54909

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIQAAEISAILKDQIKNFGQDAEVAEVGQVLSVGDGIARVYGLDKVQAGEMVEFPGGIR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECCCCCE
GMVLNLETDNVGVVIFGDDRDIKEGDTVKRTGAIVEVPAGKELLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
LNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVGRGQRELIIGDRQTGKTAIAL
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHH
DTILNQANYNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEETGAMAYTTVVAATASDP
HHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
APMQYLAPYSATAMGEYFRDNGMDALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERSAKLNEANGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFFQ
HHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEHHHHHH
GIRPAVNTGLSVSRVGSAAQTKAMKSVAGPVKLELAQYREMAAFAQFGSDLDAATQKLLN
CCCHHHHCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RGARLTELMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVRDVTKWEHGLLQYLRNQKADL
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
LEDMTKNDRKVAGELEDAIKAALDGYAKTYA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIQAAEISAILKDQIKNFGQDAEVAEVGQVLSVGDGIARVYGLDKVQAGEMVEFPGGIR
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECCCCCE
GMVLNLETDNVGVVIFGDDRDIKEGDTVKRTGAIVEVPAGKELLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
LNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVGRGQRELIIGDRQTGKTAIAL
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHH
DTILNQANYNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEETGAMAYTTVVAATASDP
HHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
APMQYLAPYSATAMGEYFRDNGMDALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERSAKLNEANGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFFQ
HHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEHHHHHH
GIRPAVNTGLSVSRVGSAAQTKAMKSVAGPVKLELAQYREMAAFAQFGSDLDAATQKLLN
CCCHHHHCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RGARLTELMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVRDVTKWEHGLLQYLRNQKADL
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
LEDMTKNDRKVAGELEDAIKAALDGYAKTYA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA