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The map label for this gene is ctaA [H]

Identifier: 119386407

GI number: 119386407

Start: 847745

End: 848920

Strand: Direct

Name: ctaA [H]

Synonym: Pden_3699

Alternate gene names: 119386407

Gene position: 847745-848920 (Clockwise)

Preceding gene: 119386406

Following gene: 119386408

Centisome position: 49.0

GC content: 67.26

Gene sequence:

>1176_bases
ATGTCGCGCCCGATCGAGAAGGAAGCTGACATGGCAAGACGTCCCGTCTTTCAGGAAGTCACCGAGACGACCCCGCCCGG
CACGACGCCCTCCGGCGGCATGATCGATGCCGGCCACAAGGGCGCGCGCGGCGCGATCCGCCTTTGGCTGGTCGTGCTGT
TCGTCATGGTTGCGGCGATGATCGCGCTTGGCGGTGCGACGCGGCTGACCGGCTCGGGCCTGTCGATCACCGAATGGAAG
CCGGTGACCGGGGCGATCCCGCCGATGGATGCCGCCACCTGGCAGGCCGAGTTCGACAAATACCGGCAGATCCCGCAGTT
CGAGCTGGTCAATTCCGATATGGACCTGGCGAGCTTCAAGCGGATCTACTGGTGGGAATGGTCGCATCGGCTGCTGGGGC
GGCTGGTGGGGCTGGTCTGGGCGGCGGGCTTCGTCTTCTTCCTGGCGACCAGGCGCATTCCCACCGGCTGGACGCCGCGG
CTGCTGTTGCTGGGCGCGCTGGGGGGCGCGCAGGGCGCGATCGGCTGGTGGATGGTGCATTCGGGACTGTCGGGCGAGAT
GGTGCGCGTGGCCTCCTATCGGCTGGCGACGCATCTGGGGCTGGCCTTTGCCATTCTTGGCCTGATCGCCTGGTATGTGC
TGGCGCTGTCGCGGTCCGAGGCGGCGCTTTTGCGCGCCCGCCGGGCCGGCGAGGCCAAGCTTTTCTCGATGACCACCGGG
CTGATGCACCTGGCCTTCGTCCAGATCCTGCTGGGGGCGCTGGTCGCGGGGATCGATGCGGGGCGCATGTATACCGGCTG
GCCGACCATGGGCGGCGAATGGATCCCGGCCGAGATCTGGGACGCGACGCTGGGCTGGCGCAACTTCTTCGAAAACCCGG
CGCTGGTGCAGTTCATCCACCGCATGACGGGCTATCTGCTGGCGGTCTTTGCGGTGGTGGTGTTCCTGCGCGCCCGCCGT
TCGCCGCATCCGGTGACGCGCGGCGCCTATGTCGCGATGCTGGTCGCGCTGGCCGTGCAGGTGGCGCTTGGCATCATGAA
CGTGCTGCATGCCTCGCCGCTGCCTTTGGCACTGGCGCATCAGATCGGAGCCGTGGCACTGTTCACTCTGATCCTGCGCG
CGCGGCACCATGCGCGCTATCCTTATGAAACTTCGGTCCGGGGAACTGTCCGATGA

Upstream 100 bases:

>100_bases
TCGCGACTGCCGCTGACCCGCGCCGATACGCGCATCTTCCACGGCATGCTGCGGCAACTGATCCGCCGCGGCTGATTGAT
TTCCGGGTGCGCGCGGGCCA

Downstream 100 bases:

>100_bases
GCGCTTTCGACGATCTTCTCGCCTTCCAGCGCCAGACCGAGGCGCTGTCCTCGGTCGCCGAACGGCTGGCCTGGGACCAG
GAAACCGTGATGCCGCGGGG

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSRPIEKEADMARRPVFQEVTETTPPGTTPSGGMIDAGHKGARGAIRLWLVVLFVMVAAMIALGGATRLTGSGLSITEWK
PVTGAIPPMDAATWQAEFDKYRQIPQFELVNSDMDLASFKRIYWWEWSHRLLGRLVGLVWAAGFVFFLATRRIPTGWTPR
LLLLGALGGAQGAIGWWMVHSGLSGEMVRVASYRLATHLGLAFAILGLIAWYVLALSRSEAALLRARRAGEAKLFSMTTG
LMHLAFVQILLGALVAGIDAGRMYTGWPTMGGEWIPAEIWDATLGWRNFFENPALVQFIHRMTGYLLAVFAVVVFLRARR
SPHPVTRGAYVAMLVALAVQVALGIMNVLHASPLPLALAHQIGAVALFTLILRARHHARYPYETSVRGTVR

Sequences:

>Translated_391_residues
MSRPIEKEADMARRPVFQEVTETTPPGTTPSGGMIDAGHKGARGAIRLWLVVLFVMVAAMIALGGATRLTGSGLSITEWK
PVTGAIPPMDAATWQAEFDKYRQIPQFELVNSDMDLASFKRIYWWEWSHRLLGRLVGLVWAAGFVFFLATRRIPTGWTPR
LLLLGALGGAQGAIGWWMVHSGLSGEMVRVASYRLATHLGLAFAILGLIAWYVLALSRSEAALLRARRAGEAKLFSMTTG
LMHLAFVQILLGALVAGIDAGRMYTGWPTMGGEWIPAEIWDATLGWRNFFENPALVQFIHRMTGYLLAVFAVVVFLRARR
SPHPVTRGAYVAMLVALAVQVALGIMNVLHASPLPLALAHQIGAVALFTLILRARHHARYPYETSVRGTVR
>Mature_390_residues
SRPIEKEADMARRPVFQEVTETTPPGTTPSGGMIDAGHKGARGAIRLWLVVLFVMVAAMIALGGATRLTGSGLSITEWKP
VTGAIPPMDAATWQAEFDKYRQIPQFELVNSDMDLASFKRIYWWEWSHRLLGRLVGLVWAAGFVFFLATRRIPTGWTPRL
LLLGALGGAQGAIGWWMVHSGLSGEMVRVASYRLATHLGLAFAILGLIAWYVLALSRSEAALLRARRAGEAKLFSMTTGL
MHLAFVQILLGALVAGIDAGRMYTGWPTMGGEWIPAEIWDATLGWRNFFENPALVQFIHRMTGYLLAVFAVVVFLRARRS
PHPVTRGAYVAMLVALAVQVALGIMNVLHASPLPLALAHQIGAVALFTLILRARHHARYPYETSVRGTVR

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=369, Percent_Identity=38.4823848238482, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI17921987, Length=337, Percent_Identity=37.3887240356083, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17536069, Length=387, Percent_Identity=35.1421188630491, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320989, Length=398, Percent_Identity=35.929648241206, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI19922860, Length=336, Percent_Identity=37.202380952381, Blast_Score=195, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 42949; Mature: 42818

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPIEKEADMARRPVFQEVTETTPPGTTPSGGMIDAGHKGARGAIRLWLVVLFVMVAAM
CCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IALGGATRLTGSGLSITEWKPVTGAIPPMDAATWQAEFDKYRQIPQFELVNSDMDLASFK
HHHCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHH
RIYWWEWSHRLLGRLVGLVWAAGFVFFLATRRIPTGWTPRLLLLGALGGAQGAIGWWMVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHH
SGLSGEMVRVASYRLATHLGLAFAILGLIAWYVLALSRSEAALLRARRAGEAKLFSMTTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LMHLAFVQILLGALVAGIDAGRMYTGWPTMGGEWIPAEIWDATLGWRNFFENPALVQFIH
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
RMTGYLLAVFAVVVFLRARRSPHPVTRGAYVAMLVALAVQVALGIMNVLHASPLPLALAH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QIGAVALFTLILRARHHARYPYETSVRGTVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRPIEKEADMARRPVFQEVTETTPPGTTPSGGMIDAGHKGARGAIRLWLVVLFVMVAAM
CCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IALGGATRLTGSGLSITEWKPVTGAIPPMDAATWQAEFDKYRQIPQFELVNSDMDLASFK
HHHCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHH
RIYWWEWSHRLLGRLVGLVWAAGFVFFLATRRIPTGWTPRLLLLGALGGAQGAIGWWMVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHH
SGLSGEMVRVASYRLATHLGLAFAILGLIAWYVLALSRSEAALLRARRAGEAKLFSMTTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LMHLAFVQILLGALVAGIDAGRMYTGWPTMGGEWIPAEIWDATLGWRNFFENPALVQFIH
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
RMTGYLLAVFAVVVFLRARRSPHPVTRGAYVAMLVALAVQVALGIMNVLHASPLPLALAH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QIGAVALFTLILRARHHARYPYETSVRGTVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA