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The map label for this gene is mshA [H]

Identifier: 119386363

GI number: 119386363

Start: 806209

End: 807537

Strand: Direct

Name: mshA [H]

Synonym: Pden_3655

Alternate gene names: 119386363

Gene position: 806209-807537 (Clockwise)

Preceding gene: 119386361

Following gene: 119386364

Centisome position: 46.6

GC content: 69.0

Gene sequence:

>1329_bases
ATGGTCGAGGCGGATTTGACGCGGGAATCGGATGGGAGCGGCAAGAGGCTGTCCGTTCTGTTGCTGGCGGATGATTGCAA
CCCGGAATGGCCCTCGTTGCCGATCGTGGGCTACAAATACGCCCTCGCGCTTGGCCGGGTGGCCCGCGTCGTGGTCGCCA
CCCATGTCCGCAACCGCGAGAACATCCTCAAGGCCGCGCCGCAGGGGGTCGAGTTCGTCTTTCTGGACAATGAGCGCATC
GCCTCGCCGCTCCACAAGCTGGCGCTCTGGCTGCGCGGCGGCAGCGAGGTGGCCTGGTCCACCAACATGATCATGCAATA
CCTGCCCTATCTCGCCTTCGAGCGCGAGGCGTGGAAGCATTTCCGCAAGGCGCTGCGGGCGGGCGAGTTCGACCTGGTGC
ATCGCATCACCCCGATGACGCCCACGCTGCCCAGCTATATCGCGGGCAAGCTGGCGGTGCCCTTCGTCATCGGCCCGCTG
AACGGCAACCTGCCCTGGCCGCGCGAGTTCCGCAGCGAGCAGAAGCGCGAGCGCGAGCGGCTGCGCGTGTTGCGCGACGT
CGCCAAGCACCTGCCCTATGCGCGCGGCACCTATCGTAATGCCGCGCTGGTGCTGGCGGGGTTCGAGCATACGATGCGCG
AGCTGCGGCCGCTGGCGCCGGGCCGCGTGGTGAACTTCCCCGAGATCGGCTATGACCCGGCGATCTTTCACGCCGCGCGC
AAGGTGCCGGCCTTTGGCGGGCCGGGGCCCTATCGCTTTCTCTTTGCGGGCCGGCTGGTGCCCTACAAGCTGCCCGACGT
CGCGGTGCTGGCCTTTGCCGGGGCACCGGAGCTGGCCGGCCACAGCCTGCATATCGTCGGCGACGGTCCCGAGATGCCGC
GGCTGCGCGAAATCGTGGCGCAGCACGGGCTGGAGGATACCGTGCATTTCGAGGGCCGCCGCAGCCAGGCCGAGCTGGCC
GGGATGATGCGCGATTTCGACGGCTTCGTCTTTCCCTCGATCCGCGAACTGGGCGCGGGCGTGGTGATCGAGGCCATGGC
CTGCGGCATGACCTGCTTCGTCGCCGATTACGGTGCGCCGGGCCACCTGGCGGGCCGGGGGCGCGGCGTGACCGTGCCGA
TCCGCGACCATTCCGGCTATGTGGCGCAATTCCGGCAGGTGCTCGCCGGGGCGGTGGCCGATCCCGCCACCGCGGCCGCT
CGGGCGGCAGCCGGGCAGGGCTATGCCGAGGCCCTGTATCCCTGGGATCGCAAGGCGCAAGAGACGCTGGCCTATTACCG
CGACCTGCTGGCCGGGCGGCCGGTGCAAGACCGGGGGGATTACGATTGA

Upstream 100 bases:

>100_bases
GTTCCGCGTGCTAGGCTGCCCGCGCCAGGGTCCGGGGATTTTGGCTGGGATTTCAAGGGGCATTGCCGCGGCGCGGCGCA
GGCTTCAGTCAGGATGGCGG

Downstream 100 bases:

>100_bases
GCCTGCGCCGACGCCTGGCTGCGCTTGGCGCCGCCCTTCTTGCCGCCGCGACCCTGGCCCTGCCTGCGGCGGCGGCTCGG
GAATGCGTGGGGCAGAACCT

Product: glycosyl transferase, group 1

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MVEADLTRESDGSGKRLSVLLLADDCNPEWPSLPIVGYKYALALGRVARVVVATHVRNRENILKAAPQGVEFVFLDNERI
ASPLHKLALWLRGGSEVAWSTNMIMQYLPYLAFEREAWKHFRKALRAGEFDLVHRITPMTPTLPSYIAGKLAVPFVIGPL
NGNLPWPREFRSEQKRERERLRVLRDVAKHLPYARGTYRNAALVLAGFEHTMRELRPLAPGRVVNFPEIGYDPAIFHAAR
KVPAFGGPGPYRFLFAGRLVPYKLPDVAVLAFAGAPELAGHSLHIVGDGPEMPRLREIVAQHGLEDTVHFEGRRSQAELA
GMMRDFDGFVFPSIRELGAGVVIEAMACGMTCFVADYGAPGHLAGRGRGVTVPIRDHSGYVAQFRQVLAGAVADPATAAA
RAAAGQGYAEALYPWDRKAQETLAYYRDLLAGRPVQDRGDYD

Sequences:

>Translated_442_residues
MVEADLTRESDGSGKRLSVLLLADDCNPEWPSLPIVGYKYALALGRVARVVVATHVRNRENILKAAPQGVEFVFLDNERI
ASPLHKLALWLRGGSEVAWSTNMIMQYLPYLAFEREAWKHFRKALRAGEFDLVHRITPMTPTLPSYIAGKLAVPFVIGPL
NGNLPWPREFRSEQKRERERLRVLRDVAKHLPYARGTYRNAALVLAGFEHTMRELRPLAPGRVVNFPEIGYDPAIFHAAR
KVPAFGGPGPYRFLFAGRLVPYKLPDVAVLAFAGAPELAGHSLHIVGDGPEMPRLREIVAQHGLEDTVHFEGRRSQAELA
GMMRDFDGFVFPSIRELGAGVVIEAMACGMTCFVADYGAPGHLAGRGRGVTVPIRDHSGYVAQFRQVLAGAVADPATAAA
RAAAGQGYAEALYPWDRKAQETLAYYRDLLAGRPVQDRGDYD
>Mature_442_residues
MVEADLTRESDGSGKRLSVLLLADDCNPEWPSLPIVGYKYALALGRVARVVVATHVRNRENILKAAPQGVEFVFLDNERI
ASPLHKLALWLRGGSEVAWSTNMIMQYLPYLAFEREAWKHFRKALRAGEFDLVHRITPMTPTLPSYIAGKLAVPFVIGPL
NGNLPWPREFRSEQKRERERLRVLRDVAKHLPYARGTYRNAALVLAGFEHTMRELRPLAPGRVVNFPEIGYDPAIFHAAR
KVPAFGGPGPYRFLFAGRLVPYKLPDVAVLAFAGAPELAGHSLHIVGDGPEMPRLREIVAQHGLEDTVHFEGRRSQAELA
GMMRDFDGFVFPSIRELGAGVVIEAMACGMTCFVADYGAPGHLAGRGRGVTVPIRDHSGYVAQFRQVLAGAVADPATAAA
RAAAGQGYAEALYPWDRKAQETLAYYRDLLAGRPVQDRGDYD

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 48828; Mature: 48828

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEADLTRESDGSGKRLSVLLLADDCNPEWPSLPIVGYKYALALGRVARVVVATHVRNRE
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
NILKAAPQGVEFVFLDNERIASPLHKLALWLRGGSEVAWSTNMIMQYLPYLAFEREAWKH
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
FRKALRAGEFDLVHRITPMTPTLPSYIAGKLAVPFVIGPLNGNLPWPREFRSEQKRERER
HHHHHHCCCHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
LRVLRDVAKHLPYARGTYRNAALVLAGFEHTMRELRPLAPGRVVNFPEIGYDPAIFHAAR
HHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHH
KVPAFGGPGPYRFLFAGRLVPYKLPDVAVLAFAGAPELAGHSLHIVGDGPEMPRLREIVA
HCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHH
QHGLEDTVHFEGRRSQAELAGMMRDFDGFVFPSIRELGAGVVIEAMACGMTCFVADYGAP
HCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCCEEEEECCCCC
GHLAGRGRGVTVPIRDHSGYVAQFRQVLAGAVADPATAAARAAAGQGYAEALYPWDRKAQ
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCHHHH
ETLAYYRDLLAGRPVQDRGDYD
HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVEADLTRESDGSGKRLSVLLLADDCNPEWPSLPIVGYKYALALGRVARVVVATHVRNRE
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
NILKAAPQGVEFVFLDNERIASPLHKLALWLRGGSEVAWSTNMIMQYLPYLAFEREAWKH
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
FRKALRAGEFDLVHRITPMTPTLPSYIAGKLAVPFVIGPLNGNLPWPREFRSEQKRERER
HHHHHHCCCHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
LRVLRDVAKHLPYARGTYRNAALVLAGFEHTMRELRPLAPGRVVNFPEIGYDPAIFHAAR
HHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHH
KVPAFGGPGPYRFLFAGRLVPYKLPDVAVLAFAGAPELAGHSLHIVGDGPEMPRLREIVA
HCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHH
QHGLEDTVHFEGRRSQAELAGMMRDFDGFVFPSIRELGAGVVIEAMACGMTCFVADYGAP
HCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCCEEEEECCCCC
GHLAGRGRGVTVPIRDHSGYVAQFRQVLAGAVADPATAAARAAAGQGYAEALYPWDRKAQ
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCHHHH
ETLAYYRDLLAGRPVQDRGDYD
HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA