Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 119386341

GI number: 119386341

Start: 784178

End: 785338

Strand: Direct

Name: yngJ [H]

Synonym: Pden_3633

Alternate gene names: 119386341

Gene position: 784178-785338 (Clockwise)

Preceding gene: 119386338

Following gene: 119386342

Centisome position: 45.33

GC content: 65.29

Gene sequence:

>1161_bases
ATGTTCAACGCGGGAATGCAGTTCGATCTGGGCGAGGACGTGAACGCGCTGCGCGAGACCGTGCACCGCTGGGCGCAGGA
GCGGGTGAAGCCCATCGCGGCCGAGGTGGATCGCAAGAACGCATTCCCGAACGAGCTGTGGCGCGAGATGGGCGATCTGG
GCCTTCTGGGCATCACCGTGTCCGAAGAACTTGGCGGCAGCGGCATGGGCTATCTGGCCCATGTCGTCGCGACCGAGGAG
ATCGCCCGCGCCTCGGCCTCGGTCAGCCTGTCCTATGGCGCGCATTCGAATCTTTGCGTGAACCAGATCAAGCTGAACGG
CACCGATGAGCAGCGGGCGAAATACCTGCCCAAGCTTTGCTCGGGCGAGCATGTCGGCGCGCTGGCCATGTCCGAGGAGG
GTGCGGGCAGCGACGTCGTCGGCATGAAGCTGCGCGCCGAAAAGCGCAACGACCGCTATGTGCTGAACGGCAACAAATAC
TGGATCACCAACGCGCCGGACGCCCATACGCTGGTGGTCTATGCCAAGACCGATCCCGAGGCGGGCAGCAAGGGCATCAC
CGCCTTCATCGTCGAGCGCGGCATGAAGGGTTTCTCGACCAGCCCGCATTTCGACAAGCTGGGCATGCGCGGCTCGAACA
CCGGCGAGCTGATCTTCGAGGATTGCGAGGTGCCCTTCGAGAACGTGCTGGGCGCCGAGGGCAAGGGCGTGCGCGTGCTG
ATGTCGGGCCTCGACTACGAGCGGCTGGTGCTGTCGGGCATCGGCACCGGCATCATGGCCGCCTGCCTCGACGAGGTCAT
GCCCTATGTCAAGGAGCGCAAGCAGTTCGGCCAGCCTATCGGGTCGTTCCAGCTGATGCAGGGCAAGATCGCCGACATGT
ATGTCGCGCTGAACACGGCGCGGGCCTATGTCTACGAGGTGGCGAAGGCTTGCGACGCGGGCAAGGTTACCCGGCAAGAC
GCGGCGGGCGCGGTGCTTTACGCCAGCGAGCAGGCCATGGTGCAGGCGCATCAGGCGGTGCAGGCGCTGGGGGGTGCGGG
TTTCCTCAACGATTCGGTGGTCAGCCGGCTGTTCCGCGATGCCAAGCTGATGGAGATCGGTGCCGGCACCAGCGAGATCC
GCCGCATGCTGATCGGCCGCGAGCTTCTGGGGCTGGCCTGA

Upstream 100 bases:

>100_bases
GGCAGGGGAGATGCCGCGACAGAAGGCTTGACGCAGGCCACGCTCCGGCGGCATAAGACAGTTAAATGAACACTTGTTCA
ATAAATGGAGGAGATCGCCG

Downstream 100 bases:

>100_bases
TGGCCGGCTTGCGGCGCGTGCTGGTCCTTGGTGCGCTGGTGGTGCTTGGCACCGGCACCGCCGTGGCGCAGCAACAGAAT
GGCGGGCCGGCCTTCGACGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 3-methylbut-2-enoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFNAGMQFDLGEDVNALRETVHRWAQERVKPIAAEVDRKNAFPNELWREMGDLGLLGITVSEELGGSGMGYLAHVVATEE
IARASASVSLSYGAHSNLCVNQIKLNGTDEQRAKYLPKLCSGEHVGALAMSEEGAGSDVVGMKLRAEKRNDRYVLNGNKY
WITNAPDAHTLVVYAKTDPEAGSKGITAFIVERGMKGFSTSPHFDKLGMRGSNTGELIFEDCEVPFENVLGAEGKGVRVL
MSGLDYERLVLSGIGTGIMAACLDEVMPYVKERKQFGQPIGSFQLMQGKIADMYVALNTARAYVYEVAKACDAGKVTRQD
AAGAVLYASEQAMVQAHQAVQALGGAGFLNDSVVSRLFRDAKLMEIGAGTSEIRRMLIGRELLGLA

Sequences:

>Translated_386_residues
MFNAGMQFDLGEDVNALRETVHRWAQERVKPIAAEVDRKNAFPNELWREMGDLGLLGITVSEELGGSGMGYLAHVVATEE
IARASASVSLSYGAHSNLCVNQIKLNGTDEQRAKYLPKLCSGEHVGALAMSEEGAGSDVVGMKLRAEKRNDRYVLNGNKY
WITNAPDAHTLVVYAKTDPEAGSKGITAFIVERGMKGFSTSPHFDKLGMRGSNTGELIFEDCEVPFENVLGAEGKGVRVL
MSGLDYERLVLSGIGTGIMAACLDEVMPYVKERKQFGQPIGSFQLMQGKIADMYVALNTARAYVYEVAKACDAGKVTRQD
AAGAVLYASEQAMVQAHQAVQALGGAGFLNDSVVSRLFRDAKLMEIGAGTSEIRRMLIGRELLGLA
>Mature_386_residues
MFNAGMQFDLGEDVNALRETVHRWAQERVKPIAAEVDRKNAFPNELWREMGDLGLLGITVSEELGGSGMGYLAHVVATEE
IARASASVSLSYGAHSNLCVNQIKLNGTDEQRAKYLPKLCSGEHVGALAMSEEGAGSDVVGMKLRAEKRNDRYVLNGNKY
WITNAPDAHTLVVYAKTDPEAGSKGITAFIVERGMKGFSTSPHFDKLGMRGSNTGELIFEDCEVPFENVLGAEGKGVRVL
MSGLDYERLVLSGIGTGIMAACLDEVMPYVKERKQFGQPIGSFQLMQGKIADMYVALNTARAYVYEVAKACDAGKVTRQD
AAGAVLYASEQAMVQAHQAVQALGGAGFLNDSVVSRLFRDAKLMEIGAGTSEIRRMLIGRELLGLA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=60.8, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI226958414, Length=338, Percent_Identity=63.0177514792899, Blast_Score=440, Evalue=1e-124,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=40.5333333333333, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI4501859, Length=366, Percent_Identity=36.8852459016393, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI4501857, Length=385, Percent_Identity=32.4675324675325, Blast_Score=224, Evalue=8e-59,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=35, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=35, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=35.7894736842105, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=33.5978835978836, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=34.2857142857143, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=34.2857142857143, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI4503943, Length=386, Percent_Identity=31.8652849740933, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI7669494, Length=357, Percent_Identity=32.7731092436975, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI48976061, Length=282, Percent_Identity=26.9503546099291, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI211971008, Length=282, Percent_Identity=26.9503546099291, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=21.6312056737589, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=29.0575916230367, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI87081958, Length=350, Percent_Identity=30.5714285714286, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=25.8687258687259, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081702, Length=293, Percent_Identity=25.5972696245734, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=57.8249336870027, Blast_Score=458, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=36.1185983827493, Blast_Score=247, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=35.4166666666667, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=35.4330708661417, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=35.5795148247978, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=35.8638743455497, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=40.6474820143885, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=32.1808510638298, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=33.7142857142857, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=35.7664233576642, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=38.961038961039, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=29.8941798941799, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=30.5177111716621, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=29.3478260869565, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=34.3859649122807, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=30.5439330543933, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI86563381, Length=284, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=284, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=55.6430446194226, Blast_Score=430, Evalue=1e-121,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=40.3743315508021, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=37.4331550802139, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24666513, Length=371, Percent_Identity=35.8490566037736, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=36.2204724409449, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=36.1271676300578, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=28.051948051948, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.10

Molecular weight: Translated: 41712; Mature: 41712

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNAGMQFDLGEDVNALRETVHRWAQERVKPIAAEVDRKNAFPNELWREMGDLGLLGITV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEE
SEELGGSGMGYLAHVVATEEIARASASVSLSYGAHSNLCVNQIKLNGTDEQRAKYLPKLC
CHHCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHH
SGEHVGALAMSEEGAGSDVVGMKLRAEKRNDRYVLNGNKYWITNAPDAHTLVVYAKTDPE
CCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEECCCEEEEECCCCCEEEEEEEECCCC
AGSKGITAFIVERGMKGFSTSPHFDKLGMRGSNTGELIFEDCEVPFENVLGAEGKGVRVL
CCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEE
MSGLDYERLVLSGIGTGIMAACLDEVMPYVKERKQFGQPIGSFQLMQGKIADMYVALNTA
ECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHEEHHHHH
RAYVYEVAKACDAGKVTRQDAAGAVLYASEQAMVQAHQAVQALGGAGFLNDSVVSRLFRD
HHHHHHHHHHCCCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
AKLMEIGAGTSEIRRMLIGRELLGLA
CHHEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFNAGMQFDLGEDVNALRETVHRWAQERVKPIAAEVDRKNAFPNELWREMGDLGLLGITV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEE
SEELGGSGMGYLAHVVATEEIARASASVSLSYGAHSNLCVNQIKLNGTDEQRAKYLPKLC
CHHCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHH
SGEHVGALAMSEEGAGSDVVGMKLRAEKRNDRYVLNGNKYWITNAPDAHTLVVYAKTDPE
CCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEECCCEEEEECCCCCEEEEEEEECCCC
AGSKGITAFIVERGMKGFSTSPHFDKLGMRGSNTGELIFEDCEVPFENVLGAEGKGVRVL
CCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEE
MSGLDYERLVLSGIGTGIMAACLDEVMPYVKERKQFGQPIGSFQLMQGKIADMYVALNTA
ECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHEEHHHHH
RAYVYEVAKACDAGKVTRQDAAGAVLYASEQAMVQAHQAVQALGGAGFLNDSVVSRLFRD
HHHHHHHHHHCCCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
AKLMEIGAGTSEIRRMLIGRELLGLA
CHHEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-methylbutanoyl-CoA; acceptor

Specific reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]