Click here to switch to the map view.

The map label for this gene is cbrC [H]

Identifier: 119386235

GI number: 119386235

Start: 673166

End: 674206

Strand: Direct

Name: cbrC [H]

Synonym: Pden_3524

Alternate gene names: 119386235

Gene position: 673166-674206 (Clockwise)

Preceding gene: 119386234

Following gene: 119386236

Centisome position: 38.91

GC content: 72.05

Gene sequence:

>1041_bases
ATGGCCATCACCACCACCACCCTTGCCACCATCGCCGCCGCGCGGCATCGGCGCGGCCGCCGGCGCCGGGCCATCCTTGC
CGGCCTGGTCCTGCTGATCGCGGGGATGCTTGCGCTGACGCTGATGCTGGGCCAGTCCTTCACCCCGCCGGGGCAAGTCA
TCCGCGTGCTTGCCGGGCAAGAGGTGCCCGGCGCCTCGTTCACGGTGCGGCAATTGCGGCTGCCAAGGGCGGTGCTGTCG
GTGCTGGCCGGGTTCTGCTTCGGCATGGGCGGCGTCGCCTTCCAGATCATGCTGCGCAACCCGCTGGCCAGTCCCGACAT
CATCGGCATCAGCTCGGGCGCCAGCGCGGCGGCGGTGTTCGCCATCGTGGTGCTGGGGATCAGCGGGCCGGCGGTGCCGA
TCCTGGCCGTGGCGGCGGGGCTGGGCGTGGCGCTGGCCATCTATGGGCTGTCCTTTCGCGGCGGCGTCGCTGGCACCCGG
CTGATCCTGATCGGCATCGGGGTCGCCGCCATGCTGCACAGCTTCATCGCCTATACGCTGTCGCGCGCGCCGGCCTGGGA
TCTGCAGCAGGCGCTGCGCTGGCTGACCGGCAGCGTCAACGGTGCCCAGCTGGGGCAGGCGCTGCCGCTGCTGGCGGTGC
TGGCGCTGGCGGGCGGCGTGTTGCTGTCCCGGTCCCGCGATCTCGAGGCGCTGCGCATGGGCGAGGACACCGCCGCCGCC
CTCGGCGTCCGGGTCGGGCCGACGCGGACGCTGGTGATCGCCTGCGCCGTCGGCATGATCGCGGTGGCGACGGCGATCAC
CGGGCCGATCTCTTTCGTCGCCTTCCTGTCGGGACCGATCGCTGCGCGGATCATGGGCAGCGGCGGCTCGCTTTTGCTGC
CCTCGGCACTGGTCGGCGCGGCGCTGGTGCTGGTCGGCGACTATTGCGGGCAATTCCTGATGCCGGGCCGCTATCCGGTC
GGCGTCGTCACCGGGGCGCTGGGGGCGCCCTATCTGATCTACCTGATCGTGCGGGTGAACCGCGCAGGAGGCTCGCTGTG
A

Upstream 100 bases:

>100_bases
CCCGGCCGGGCGAGCTTGACGTGGGCATCGTCACCGCCTTTGTCGGCGCGCCCTTCTTCATCTGGATCGTGCGCCGCCAG
CGCCTGCGCGAGCTGTGACC

Downstream 100 bases:

>100_bases
CCGCCGACCACCGACTGATCGCCGAGCATCTGACCGCCGGCTATGGCGATGCCGCCATCCTGCGCGACCTGGACCTTGCC
GTCGCGCCGGGCCGGATCAC

Product: transport system permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAITTTTLATIAAARHRRGRRRRAILAGLVLLIAGMLALTLMLGQSFTPPGQVIRVLAGQEVPGASFTVRQLRLPRAVLS
VLAGFCFGMGGVAFQIMLRNPLASPDIIGISSGASAAAVFAIVVLGISGPAVPILAVAAGLGVALAIYGLSFRGGVAGTR
LILIGIGVAAMLHSFIAYTLSRAPAWDLQQALRWLTGSVNGAQLGQALPLLAVLALAGGVLLSRSRDLEALRMGEDTAAA
LGVRVGPTRTLVIACAVGMIAVATAITGPISFVAFLSGPIAARIMGSGGSLLLPSALVGAALVLVGDYCGQFLMPGRYPV
GVVTGALGAPYLIYLIVRVNRAGGSL

Sequences:

>Translated_346_residues
MAITTTTLATIAAARHRRGRRRRAILAGLVLLIAGMLALTLMLGQSFTPPGQVIRVLAGQEVPGASFTVRQLRLPRAVLS
VLAGFCFGMGGVAFQIMLRNPLASPDIIGISSGASAAAVFAIVVLGISGPAVPILAVAAGLGVALAIYGLSFRGGVAGTR
LILIGIGVAAMLHSFIAYTLSRAPAWDLQQALRWLTGSVNGAQLGQALPLLAVLALAGGVLLSRSRDLEALRMGEDTAAA
LGVRVGPTRTLVIACAVGMIAVATAITGPISFVAFLSGPIAARIMGSGGSLLLPSALVGAALVLVGDYCGQFLMPGRYPV
GVVTGALGAPYLIYLIVRVNRAGGSL
>Mature_345_residues
AITTTTLATIAAARHRRGRRRRAILAGLVLLIAGMLALTLMLGQSFTPPGQVIRVLAGQEVPGASFTVRQLRLPRAVLSV
LAGFCFGMGGVAFQIMLRNPLASPDIIGISSGASAAAVFAIVVLGISGPAVPILAVAAGLGVALAIYGLSFRGGVAGTRL
ILIGIGVAAMLHSFIAYTLSRAPAWDLQQALRWLTGSVNGAQLGQALPLLAVLALAGGVLLSRSRDLEALRMGEDTAAAL
GVRVGPTRTLVIACAVGMIAVATAITGPISFVAFLSGPIAARIMGSGGSLLLPSALVGAALVLVGDYCGQFLMPGRYPVG
VVTGALGAPYLIYLIVRVNRAGGSL

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=297, Percent_Identity=37.7104377104377, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790740, Length=298, Percent_Identity=33.5570469798658, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=33.0097087378641, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=32, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788004, Length=304, Percent_Identity=27.6315789473684, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=30.6859205776173, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35077; Mature: 34945

Theoretical pI: Translated: 12.09; Mature: 12.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITTTTLATIAAARHRRGRRRRAILAGLVLLIAGMLALTLMLGQSFTPPGQVIRVLAGQ
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
EVPGASFTVRQLRLPRAVLSVLAGFCFGMGGVAFQIMLRNPLASPDIIGISSGASAAAVF
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
AIVVLGISGPAVPILAVAAGLGVALAIYGLSFRGGVAGTRLILIGIGVAAMLHSFIAYTL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRAPAWDLQQALRWLTGSVNGAQLGQALPLLAVLALAGGVLLSRSRDLEALRMGEDTAAA
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
LGVRVGPTRTLVIACAVGMIAVATAITGPISFVAFLSGPIAARIMGSGGSLLLPSALVGA
HCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHH
ALVLVGDYCGQFLMPGRYPVGVVTGALGAPYLIYLIVRVNRAGGSL
HHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
AITTTTLATIAAARHRRGRRRRAILAGLVLLIAGMLALTLMLGQSFTPPGQVIRVLAGQ
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
EVPGASFTVRQLRLPRAVLSVLAGFCFGMGGVAFQIMLRNPLASPDIIGISSGASAAAVF
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
AIVVLGISGPAVPILAVAAGLGVALAIYGLSFRGGVAGTRLILIGIGVAAMLHSFIAYTL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRAPAWDLQQALRWLTGSVNGAQLGQALPLLAVLALAGGVLLSRSRDLEALRMGEDTAAA
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
LGVRVGPTRTLVIACAVGMIAVATAITGPISFVAFLSGPIAARIMGSGGSLLLPSALVGA
HCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHH
ALVLVGDYCGQFLMPGRYPVGVVTGALGAPYLIYLIVRVNRAGGSL
HHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]