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The map label for this gene is siaT [H]

Identifier: 119386193

GI number: 119386193

Start: 628308

End: 629591

Strand: Direct

Name: siaT [H]

Synonym: Pden_3482

Alternate gene names: 119386193

Gene position: 628308-629591 (Clockwise)

Preceding gene: 119386192

Following gene: 119386194

Centisome position: 36.32

GC content: 65.11

Gene sequence:

>1284_bases
GTGATCTGGCTTGGCTCGATTTTCGTCCTGACGCTGGCCCTGGGCATGCCGATCGCCTTCGTGCTGGGCATCAGCGCGCT
GGGTTACTTCTATTTCACCGGCCAGACGCAATTCCTGATCGTGTTGCCGCAGCGGATGCTGGCGGGAATGGACATGTTCG
TGCTGCTGGCGATCCCGCTTTTCGTGCTGGCGGGCGCGATCATGGACGTGGGTGGGCTGACCCGTCGCCTGATCGGCTTT
GCCAACTCGGTCGTCGGGCGATTCCGGGGCGGGTTGTCGCTGACGGCAATCTGGGGCTGCTTCCTCTTCGGCGGCGTCAG
CGGATCGGCGGCGGCGGATGCCGCGGCCATCGGCACGGTGATGGTGCCGGACATGAAGCGGCAGGGCTATGACGTGGACT
ATTCGGCGGCGCTGATCGCGGTCTCGTCGCTGATGGCGCCGCTGGTGCCGCCCTCGATCGCCATGATCATCTACGGCGCG
CTGTCGGGCACCTCGATCTCGCAACTGCTGGTCGCGGGGCTGGCGCCGGGCTTCATGCTGGCAGTGTTCCTGTCGACCTA
TGCAGTCTGGGTCGCGCATCGCCGCGGCTATCCCAAGGCGGCAAGGCAATCGCTGGCCGCGATCCTCCGGGGTTGCTGGC
AGTCCGTCCCGGTGATGCTGCTGCCGGTCATCATTGTCGTCGGCATACGGGGCGGCATCTTCACCGCGACCGAGGCCGCC
GCGGTCGCCGCGATCTATGCGCTGATCATCGCCACCGTCGTCTATCGCGCGATGAGCTGGAGATTCCTCAAGGAAGCCTT
CGTCGCCACGGCGATCATCACCTCGGCGATCTATTTCCTGGTCGCGGTCGCCAACGTCGCCGGCTTCATCTTCGCCATCG
AGCAACTGCCGCAAAAGACCGTCGCCCTGCTGACCGGGGTTTCGGACAACAAATACGTGATCCTGCTGATGGTGAACCTG
ATCCTGCTGTTCCTGGGCATGTTCCTGGACACCATCGGCGTGCTGATCCTGACGGTGCCCGCGCTGATGGCCATCGGCAA
CATGCTGGGGCTGGAGCCGGTGCATCTGGGGGTCATGGTGGTCTTCAACGTGCTGGTCGGCTTTGTCACCCCGCCGGTCG
GGCTGTGCCTGTTCGTCATCGCCGGCGTGACCGGCCGGCCGATGGAGCGGATCGCCTACAGGGCCCTGCCGATGATCGGC
ATTGCGCTGGTCGTCCTGGCGCTGATCACGATCTTTCCCGAGATCTCGCTGTTCCTGCCGCGGGTGCTGGGGGTGGCGGG
ATGA

Upstream 100 bases:

>100_bases
GCGCGGCGCTTCTGGCGCTGCATGTCGCGCTGAACGAATTCTTCGGCATTGCGCGGGAAGAGAAGCCCGAAGAGCACCCG
ATGGGCGCGGAGGAAGCGCT

Downstream 100 bases:

>100_bases
CGGATCTTTCCGTCCAGGTCGGCCGCACCCGGCTGAAGAACCCCGTCATTGCCGCATCGGGCGAGCACCTGATCGACGAT
GCCGGCATCCTGTCGGCCAT

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIWLGSIFVLTLALGMPIAFVLGISALGYFYFTGQTQFLIVLPQRMLAGMDMFVLLAIPLFVLAGAIMDVGGLTRRLIGF
ANSVVGRFRGGLSLTAIWGCFLFGGVSGSAAADAAAIGTVMVPDMKRQGYDVDYSAALIAVSSLMAPLVPPSIAMIIYGA
LSGTSISQLLVAGLAPGFMLAVFLSTYAVWVAHRRGYPKAARQSLAAILRGCWQSVPVMLLPVIIVVGIRGGIFTATEAA
AVAAIYALIIATVVYRAMSWRFLKEAFVATAIITSAIYFLVAVANVAGFIFAIEQLPQKTVALLTGVSDNKYVILLMVNL
ILLFLGMFLDTIGVLILTVPALMAIGNMLGLEPVHLGVMVVFNVLVGFVTPPVGLCLFVIAGVTGRPMERIAYRALPMIG
IALVVLALITIFPEISLFLPRVLGVAG

Sequences:

>Translated_427_residues
MIWLGSIFVLTLALGMPIAFVLGISALGYFYFTGQTQFLIVLPQRMLAGMDMFVLLAIPLFVLAGAIMDVGGLTRRLIGF
ANSVVGRFRGGLSLTAIWGCFLFGGVSGSAAADAAAIGTVMVPDMKRQGYDVDYSAALIAVSSLMAPLVPPSIAMIIYGA
LSGTSISQLLVAGLAPGFMLAVFLSTYAVWVAHRRGYPKAARQSLAAILRGCWQSVPVMLLPVIIVVGIRGGIFTATEAA
AVAAIYALIIATVVYRAMSWRFLKEAFVATAIITSAIYFLVAVANVAGFIFAIEQLPQKTVALLTGVSDNKYVILLMVNL
ILLFLGMFLDTIGVLILTVPALMAIGNMLGLEPVHLGVMVVFNVLVGFVTPPVGLCLFVIAGVTGRPMERIAYRALPMIG
IALVVLALITIFPEISLFLPRVLGVAG
>Mature_427_residues
MIWLGSIFVLTLALGMPIAFVLGISALGYFYFTGQTQFLIVLPQRMLAGMDMFVLLAIPLFVLAGAIMDVGGLTRRLIGF
ANSVVGRFRGGLSLTAIWGCFLFGGVSGSAAADAAAIGTVMVPDMKRQGYDVDYSAALIAVSSLMAPLVPPSIAMIIYGA
LSGTSISQLLVAGLAPGFMLAVFLSTYAVWVAHRRGYPKAARQSLAAILRGCWQSVPVMLLPVIIVVGIRGGIFTATEAA
AVAAIYALIIATVVYRAMSWRFLKEAFVATAIITSAIYFLVAVANVAGFIFAIEQLPQKTVALLTGVSDNKYVILLMVNL
ILLFLGMFLDTIGVLILTVPALMAIGNMLGLEPVHLGVMVVFNVLVGFVTPPVGLCLFVIAGVTGRPMERIAYRALPMIG
IALVVLALITIFPEISLFLPRVLGVAG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=373, Percent_Identity=39.4101876675603, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45127; Mature: 45127

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCC
>Mature Secondary Structure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HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]