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The map label for this gene is erg3 [H]

Identifier: 119357376

GI number: 119357376

Start: 1790476

End: 1791270

Strand: Direct

Name: erg3 [H]

Synonym: Cpha266_1574

Alternate gene names: 119357376

Gene position: 1790476-1791270 (Clockwise)

Preceding gene: 119357375

Following gene: 119357384

Centisome position: 57.13

GC content: 55.35

Gene sequence:

>795_bases
ATGGCAGATATCTTTTTTTCCATACCCGACCTCCGCATACTCTCGTACGGCACGACCATTGCCGGAGGAGTGCTGCTCTG
GATCCTCGAAGGCCTCTTCCCTTTTTTTTCCGGACAGAAACGCCGCGACCTCCATGCAAGGCTCAACCTTTCGATGGCAG
GGCTCAACCTGCTGATCCTGCTCCCTTCGGGCATACTTATGGCATTCGTGCTCGAATGGTCGAAAAACGTCTGGCCGGGA
ATCGGGATGCTGGCCCTTCACCCCCTTGCCGAAGCAGTCCTGATCATTCTCGTCATCGACCTATGGATGTACGTCTGGCA
TCGTCTCAACCATGAAACGGCATTTCTCTGGAGATTCCACTCGGTACACCACAGCGACGCATCGCTCGACGTCACAACCA
GTTGGCGGTTCCATTACATGGAGATTCTGATTTCGGAGATGCTGCGGCTCCCCCTCTTCATGCTCATGGGCGCAGGTATC
GAACACCTGCTGCTCTACTCGCTCCTTATGACACCAGTCATCGAATTCCACCACAGCAATATCTCTGTTCCGCGCGCTCT
GGATCGTCTGGTACGGATCGTCATCCCATCCCCCATCATGCACCGCCTGCATCACTCGAGAGAAAGAAGCGAACACGACT
CCAACTACGGCAGCATGCTCTCCCTGTGGGACCGACTCTTCGGCAGCTTTCTGATGAAAGAGAGTCTCGACGGTCTCCGT
CTCGGTCTCGATCACGAAAGTGACTCCGACAAGCAACGAATCCTCGCCCTGCTCCAGAGACCCTTCCGCCCATAA

Upstream 100 bases:

>100_bases
GAATCATAGCTGACCAAGCTTACGCGTATTCAATAACAGATATTTTTATGGAGGGCAACGAGCGGATAAGAGCGGTTCAA
TCGGTTCTTCCGAAAACAGC

Downstream 100 bases:

>100_bases
CGAGCTACCGGCGCCGTTCGACCATCACAGCCCAGACCGGATCATACCCGTGAATATCGTCCGTCGTACCCGACGCATCG
ACGACCGGACGACCCTCGTT

Product: sterol desaturase, putative

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MADIFFSIPDLRILSYGTTIAGGVLLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLILLPSGILMAFVLEWSKNVWPG
IGMLALHPLAEAVLIILVIDLWMYVWHRLNHETAFLWRFHSVHHSDASLDVTTSWRFHYMEILISEMLRLPLFMLMGAGI
EHLLLYSLLMTPVIEFHHSNISVPRALDRLVRIVIPSPIMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLMKESLDGLR
LGLDHESDSDKQRILALLQRPFRP

Sequences:

>Translated_264_residues
MADIFFSIPDLRILSYGTTIAGGVLLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLILLPSGILMAFVLEWSKNVWPG
IGMLALHPLAEAVLIILVIDLWMYVWHRLNHETAFLWRFHSVHHSDASLDVTTSWRFHYMEILISEMLRLPLFMLMGAGI
EHLLLYSLLMTPVIEFHHSNISVPRALDRLVRIVIPSPIMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLMKESLDGLR
LGLDHESDSDKQRILALLQRPFRP
>Mature_263_residues
ADIFFSIPDLRILSYGTTIAGGVLLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLILLPSGILMAFVLEWSKNVWPGI
GMLALHPLAEAVLIILVIDLWMYVWHRLNHETAFLWRFHSVHHSDASLDVTTSWRFHYMEILISEMLRLPLFMLMGAGIE
HLLLYSLLMTPVIEFHHSNISVPRALDRLVRIVIPSPIMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLMKESLDGLRL
GLDHESDSDKQRILALLQRPFRP

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=154, Percent_Identity=27.9220779220779, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 30519; Mature: 30387

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIFFSIPDLRILSYGTTIAGGVLLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLIL
CCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEH
LPSGILMAFVLEWSKNVWPGIGMLALHPLAEAVLIILVIDLWMYVWHRLNHETAFLWRFH
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SVHHSDASLDVTTSWRFHYMEILISEMLRLPLFMLMGAGIEHLLLYSLLMTPVIEFHHSN
HHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
ISVPRALDRLVRIVIPSPIMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLMKESLDGLR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHE
LGLDHESDSDKQRILALLQRPFRP
ECCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADIFFSIPDLRILSYGTTIAGGVLLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLIL
CCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEH
LPSGILMAFVLEWSKNVWPGIGMLALHPLAEAVLIILVIDLWMYVWHRLNHETAFLWRFH
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SVHHSDASLDVTTSWRFHYMEILISEMLRLPLFMLMGAGIEHLLLYSLLMTPVIEFHHSN
HHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
ISVPRALDRLVRIVIPSPIMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLMKESLDGLR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHE
LGLDHESDSDKQRILALLQRPFRP
ECCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]