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The map label for this gene is hldE [H]

Identifier: 119357328

GI number: 119357328

Start: 1734105

End: 1735088

Strand: Direct

Name: hldE [H]

Synonym: Cpha266_1526

Alternate gene names: 119357328

Gene position: 1734105-1735088 (Clockwise)

Preceding gene: 119357321

Following gene: 119357333

Centisome position: 55.33

GC content: 46.95

Gene sequence:

>984_bases
ATGTCAGCACCCTCCATAAAACACATCCTTGATTCGTTCAAGAAGCAGCGCATTGCCGTTATAGGCGACATCATGCTCGA
TAAATATATCTTCGGGCATGTTTCAAGAATTTCTCCGGAGTATCCGGTTCCTGTCGTTGAGGTAACGCATGAGGATCATC
GGCTCGGCGGAGCTGCAAATGTCGCTCTCAATACGCTTTCGCTTGGCGCTGAAACCATCCTGATCGGGGTTACCGGTGCT
GATGCCAACAGGGATATTCTTGCAGACCTTTGCAGAAATCTGAACCTTTCCGTTGACTGTCTCGTTGCGGACGCATCAAG
ACCCACAACAAGCAAAACAAGAATTCTCTCCCAAAGCCATCACATAACCAGAGTGGATTATGAAAGCAAGGAGTCGGTTG
ACCAGCATATTGAAACCGCCATTCTTGAGCGTTTTGAACATATTGCCGACAGCATTGATGCCGTGATTCTCGAAGATTAC
AACAAGGGACTTCTTACGGAAAACCTTGTTCAAAACATTATTAAAATAGCAGAAACAAACAACACCCCCGTTCTTGTTGA
CCCTAAACTTAAAGGGTTCTTTTCATATCGAAACTGCAGTGTTTTCAAGCCAAACCTTTCTGAAATGGCCTCCTCACTGG
GTATTGTCATTCATAATGATGACAGGGAAATTGAGAAGGCATGCGTTTTGCTCCGCGAAAAACTCAATGCCGAGGCGATT
GTCGTAACACGAAGTGAAAAAGGAATGACCATTTACAACGGGAAATTCACTCATATTCCGGCTACATCCCTTGAAGTATC
CGATGTATCGGGTGCCGGAGACACGGTAATCAGCGTGCTCGCGCTGGGTGCCGCTTCCGGTCTCGATATTGAGACCAGCG
CAGCAATCGCCAATCTTGCTGCCGGATCAGTCTGCCAGGAGGTTGGCGCCGTTCCTGTAAAACAGGATAAACTGTTCAGG
GCATGTCAGGAATATCTTCGATAA

Upstream 100 bases:

>100_bases
TCTTGTGATCTGAGTGCATATCAGGTTTTTATCCACTTTTTTCTTTTTTTGTCGAAAAGAAATCTTCTCCGTGCAATAAT
ATCGTCACCAGAAAATCAGT

Downstream 100 bases:

>100_bases
TGCAGAGGTGGTTGTCAATCTCATCAGGATATGGCGGATTATAGGAACAGTCGGCAATCAGGGATCTCATATTCTGCAAC
GAATAAAAGGGAACCTCGAA

Product: rfaE bifunctional protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSAPSIKHILDSFKKQRIAVIGDIMLDKYIFGHVSRISPEYPVPVVEVTHEDHRLGGAANVALNTLSLGAETILIGVTGA
DANRDILADLCRNLNLSVDCLVADASRPTTSKTRILSQSHHITRVDYESKESVDQHIETAILERFEHIADSIDAVILEDY
NKGLLTENLVQNIIKIAETNNTPVLVDPKLKGFFSYRNCSVFKPNLSEMASSLGIVIHNDDREIEKACVLLREKLNAEAI
VVTRSEKGMTIYNGKFTHIPATSLEVSDVSGAGDTVISVLALGAASGLDIETSAAIANLAAGSVCQEVGAVPVKQDKLFR
ACQEYLR

Sequences:

>Translated_327_residues
MSAPSIKHILDSFKKQRIAVIGDIMLDKYIFGHVSRISPEYPVPVVEVTHEDHRLGGAANVALNTLSLGAETILIGVTGA
DANRDILADLCRNLNLSVDCLVADASRPTTSKTRILSQSHHITRVDYESKESVDQHIETAILERFEHIADSIDAVILEDY
NKGLLTENLVQNIIKIAETNNTPVLVDPKLKGFFSYRNCSVFKPNLSEMASSLGIVIHNDDREIEKACVLLREKLNAEAI
VVTRSEKGMTIYNGKFTHIPATSLEVSDVSGAGDTVISVLALGAASGLDIETSAAIANLAAGSVCQEVGAVPVKQDKLFR
ACQEYLR
>Mature_326_residues
SAPSIKHILDSFKKQRIAVIGDIMLDKYIFGHVSRISPEYPVPVVEVTHEDHRLGGAANVALNTLSLGAETILIGVTGAD
ANRDILADLCRNLNLSVDCLVADASRPTTSKTRILSQSHHITRVDYESKESVDQHIETAILERFEHIADSIDAVILEDYN
KGLLTENLVQNIIKIAETNNTPVLVDPKLKGFFSYRNCSVFKPNLSEMASSLGIVIHNDDREIEKACVLLREKLNAEAIV
VTRSEKGMTIYNGKFTHIPATSLEVSDVSGAGDTVISVLALGAASGLDIETSAAIANLAAGSVCQEVGAVPVKQDKLFRA
CQEYLR

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=307, Percent_Identity=40.7166123778502, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35505; Mature: 35374

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSIKHILDSFKKQRIAVIGDIMLDKYIFGHVSRISPEYPVPVVEVTHEDHRLGGAAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCHHH
VALNTLSLGAETILIGVTGADANRDILADLCRNLNLSVDCLVADASRPTTSKTRILSQSH
HHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCC
HITRVDYESKESVDQHIETAILERFEHIADSIDAVILEDYNKGLLTENLVQNIIKIAETN
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCC
NTPVLVDPKLKGFFSYRNCSVFKPNLSEMASSLGIVIHNDDREIEKACVLLREKLNAEAI
CCCEEECCCCCCEEEECCCEEECCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEE
VVTRSEKGMTIYNGKFTHIPATSLEVSDVSGAGDTVISVLALGAASGLDIETSAAIANLA
EEEECCCCEEEECCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AGSVCQEVGAVPVKQDKLFRACQEYLR
HHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAPSIKHILDSFKKQRIAVIGDIMLDKYIFGHVSRISPEYPVPVVEVTHEDHRLGGAAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCHHH
VALNTLSLGAETILIGVTGADANRDILADLCRNLNLSVDCLVADASRPTTSKTRILSQSH
HHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCC
HITRVDYESKESVDQHIETAILERFEHIADSIDAVILEDYNKGLLTENLVQNIIKIAETN
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCC
NTPVLVDPKLKGFFSYRNCSVFKPNLSEMASSLGIVIHNDDREIEKACVLLREKLNAEAI
CCCEEECCCCCCEEEECCCEEECCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEE
VVTRSEKGMTIYNGKFTHIPATSLEVSDVSGAGDTVISVLALGAASGLDIETSAAIANLA
EEEECCCCEEEECCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AGSVCQEVGAVPVKQDKLFRACQEYLR
HHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA