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The map label for this gene is hldD [H]

Identifier: 119357223

GI number: 119357223

Start: 1609686

End: 1610687

Strand: Direct

Name: hldD [H]

Synonym: Cpha266_1414

Alternate gene names: 119357223

Gene position: 1609686-1610687 (Clockwise)

Preceding gene: 119357222

Following gene: 119357224

Centisome position: 51.36

GC content: 49.2

Gene sequence:

>1002_bases
ATGATCATCATTACCGGCGGAGCAGGATTTATCGGCAGCGCCATGCTGTGGGAGCTTAACCGGTCCGGTGAGGACAATAT
TCTGATAGTTGATGATCTCGGTTCAACGGCAGATAAAAAATGGCAGAATCTCAGCGGACTCTCCTTTGCCGACATTCTCC
CTGTCGACGCCTTTGTCCGCTGTCTTGCGGAAGACAAGTTCAACGATTGTACCGCCGTTATCCATATGGGAGCGATCAGC
GCGACTACCGAAACTGATGCCGACCTGCTCCTCGACCGAAATTACTTCTTTTCAAAAAATCTTGCCGGGTATTGCATGAA
AAAAGACATCCGGCTGATCTATGCCTCAAGCGCAGCGACCTACGGTGACGGCAAGGCAGGATACCGGGATGATGAAGAGA
AACTCCACTCGCTTCGTCCCCTGAACATGTACGGGTTTTCAAAACACCTGTTCGACTGCTGGGCGAAAAAAAACGATGTG
CTGAAAAAAAGCGCCGGACTGAAATTTTTTAACGTCTACGGCCCCAATGAGTATCACAAAGGAGAGATGACCAGCGTTGT
CTTTAAAGCATACAACCAGATACGGGAAAACGGCGTTGTCAACCTCTTTCAGTCGCACCATCCGGACTACCTTGACGGCG
AACAGCTTCGGGACTTCATCTCGGTAAGGGATTGTACGAAAATCATGACCTGGCTGCTTGAAAACCCTGAAGTTACCGGA
CTGTTCAATGTTGGCACCGGAAAAGCAAGAAGTTTCAGGGATCTTGTCACGGCAACATTTTCAGCCCTTGATCTTGATCC
GGCCATCCTCTATGTGCCGATGCCTGAAAATCTGAGGGACAAATACCAGTACTATACCTGCGCAGATACCGACAAGCTTC
AGAAAGCGGGCTATTCCGGTTCGACGACCTCGCTCGAAGATGGCATAAGGGATTATGTACAAAACTGGCTCGTAACCCTG
ACCCCACATTTTGATATCGGCCATAACACCCACAATCATTAA

Upstream 100 bases:

>100_bases
GGCCGTCTTATCGATATAAGACGGCCTTTTGTATTTATCCGCATGGCTTTATATTGCCTGAACACCGAAGAGTCTCAAAA
GAAACGAATGCCATTTTTTC

Downstream 100 bases:

>100_bases
CCCCTACGCATTTGTCCATAGAAAAAACGATTGAGATACAAGGAAGAGAACCCGTCCTTCTCTTTGGCCCCTACGACTCC
TACCTGAAAAAAATCAGAGA

Product: ADP-glyceromanno-heptose 6-epimerase precursor

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIIITGGAGFIGSAMLWELNRSGEDNILIVDDLGSTADKKWQNLSGLSFADILPVDAFVRCLAEDKFNDCTAVIHMGAIS
ATTETDADLLLDRNYFFSKNLAGYCMKKDIRLIYASSAATYGDGKAGYRDDEEKLHSLRPLNMYGFSKHLFDCWAKKNDV
LKKSAGLKFFNVYGPNEYHKGEMTSVVFKAYNQIRENGVVNLFQSHHPDYLDGEQLRDFISVRDCTKIMTWLLENPEVTG
LFNVGTGKARSFRDLVTATFSALDLDPAILYVPMPENLRDKYQYYTCADTDKLQKAGYSGSTTSLEDGIRDYVQNWLVTL
TPHFDIGHNTHNH

Sequences:

>Translated_333_residues
MIIITGGAGFIGSAMLWELNRSGEDNILIVDDLGSTADKKWQNLSGLSFADILPVDAFVRCLAEDKFNDCTAVIHMGAIS
ATTETDADLLLDRNYFFSKNLAGYCMKKDIRLIYASSAATYGDGKAGYRDDEEKLHSLRPLNMYGFSKHLFDCWAKKNDV
LKKSAGLKFFNVYGPNEYHKGEMTSVVFKAYNQIRENGVVNLFQSHHPDYLDGEQLRDFISVRDCTKIMTWLLENPEVTG
LFNVGTGKARSFRDLVTATFSALDLDPAILYVPMPENLRDKYQYYTCADTDKLQKAGYSGSTTSLEDGIRDYVQNWLVTL
TPHFDIGHNTHNH
>Mature_333_residues
MIIITGGAGFIGSAMLWELNRSGEDNILIVDDLGSTADKKWQNLSGLSFADILPVDAFVRCLAEDKFNDCTAVIHMGAIS
ATTETDADLLLDRNYFFSKNLAGYCMKKDIRLIYASSAATYGDGKAGYRDDEEKLHSLRPLNMYGFSKHLFDCWAKKNDV
LKKSAGLKFFNVYGPNEYHKGEMTSVVFKAYNQIRENGVVNLFQSHHPDYLDGEQLRDFISVRDCTKIMTWLLENPEVTG
LFNVGTGKARSFRDLVTATFSALDLDPAILYVPMPENLRDKYQYYTCADTDKLQKAGYSGSTTSLEDGIRDYVQNWLVTL
TPHFDIGHNTHNH

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=322, Percent_Identity=39.7515527950311, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37477; Mature: 37477

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIITGGAGFIGSAMLWELNRSGEDNILIVDDLGSTADKKWQNLSGLSFADILPVDAFVR
CEEEECCCCHHHHHHEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHCCHHHHHH
CLAEDKFNDCTAVIHMGAISATTETDADLLLDRNYFFSKNLAGYCMKKDIRLIYASSAAT
HHHHCCCCCCEEHEEECCCCCCCCCCCHHEEECCCCCCCCCCHHHHHCCEEEEEECCCCC
YGDGKAGYRDDEEKLHSLRPLNMYGFSKHLFDCWAKKNDVLKKSAGLKFFNVYGPNEYHK
CCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
GEMTSVVFKAYNQIRENGVVNLFQSHHPDYLDGEQLRDFISVRDCTKIMTWLLENPEVTG
CHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LFNVGTGKARSFRDLVTATFSALDLDPAILYVPMPENLRDKYQYYTCADTDKLQKAGYSG
EEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCEEEEECCHHHHHHCCCCC
STTSLEDGIRDYVQNWLVTLTPHFDIGHNTHNH
CCCCHHHHHHHHHHCCEEEECCCEECCCCCCCC
>Mature Secondary Structure
MIIITGGAGFIGSAMLWELNRSGEDNILIVDDLGSTADKKWQNLSGLSFADILPVDAFVR
CEEEECCCCHHHHHHEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHCCHHHHHH
CLAEDKFNDCTAVIHMGAISATTETDADLLLDRNYFFSKNLAGYCMKKDIRLIYASSAAT
HHHHCCCCCCEEHEEECCCCCCCCCCCHHEEECCCCCCCCCCHHHHHCCEEEEEECCCCC
YGDGKAGYRDDEEKLHSLRPLNMYGFSKHLFDCWAKKNDVLKKSAGLKFFNVYGPNEYHK
CCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
GEMTSVVFKAYNQIRENGVVNLFQSHHPDYLDGEQLRDFISVRDCTKIMTWLLENPEVTG
CHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LFNVGTGKARSFRDLVTATFSALDLDPAILYVPMPENLRDKYQYYTCADTDKLQKAGYSG
EEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCEEEEECCHHHHHHCCCCC
STTSLEDGIRDYVQNWLVTLTPHFDIGHNTHNH
CCCCHHHHHHHHHHCCEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA