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The map label for this gene is murB [H]

Identifier: 119357068

GI number: 119357068

Start: 1426865

End: 1428484

Strand: Direct

Name: murB [H]

Synonym: Cpha266_1255

Alternate gene names: 119357068

Gene position: 1426865-1428484 (Clockwise)

Preceding gene: 119357066

Following gene: 119357075

Centisome position: 45.53

GC content: 48.7

Gene sequence:

>1620_bases
ATGGAAAACCTCTCTTTGCCTTGCCCTTTTCTCAATAATGTTCATCTGTCGGAAAAAACCTATTATCAGATCGGCGGTAA
AGCACGTCTTTTTGCATTGCCTGAAAGTGTTCGACATATCGGGGATCTTCTGTGCTGGAACAGGATCCATCAGTTTCCGC
TTGCGTTGATGGGCATGGGAAGCAACACGCTTTTTTCCAGCGAGCCTTTTGAGGGTATTGTTATTTCGTTTGAAAACATG
AACCGGATGTTCTGGATTTCAGAACATGAATTATTCTGTGAAGCCGGAGTTGAAAACGGCGCCATTTCAGAAGAACTTCT
CAATAAAGAGCGGGGAGGGGGAGAGTGGCTTTACCGTTTGCCGGGACAAATCGGGTCAACGGTGAGAATGAATGCCCGGT
GTTTCGGCGGGGAGATTGCCGATGTTACGTCGGGTATTATGACTGCCTCGATAAGCGGAGCGCTTCGATGGCATAGACCG
GATGAAGTGTTTCTCGGCTACAAGAACACATCGATCATGGATCGTTCGGAAATTGTCGTAGCTGTTGTGCTCTCTTTTTC
CGCTGTGAAAAAACACGATGAGATTCAGGATCTGATGGAAAGTTTTGAAAAAGAGAGGTTTGATAAACATCATTTTGATT
ATCCGAGTTGCGGTTCAACCTTCAAGAATAATTATGAGGTCGGGCAATCGAGTGGACGGATTTTTGAAGCGCTGGGCTTC
AAGGGAGTGCGGGAGGGAGGCGCTCAGGTAAGCCCCTATCATGCAAATTTTATCTATAATACCGGCGGGGCAACCTCCTC
CGATGTGCTTCGCCTTGCAGCGAAAATGAAAACGGTGGCAGCAACCGCAATACCGGCTAAACTCGATCTCGAGGTTCAGT
GTATTGGCTTGCACCCTAAGATTCTGCTTGAGGCCTGTGGCGTTCCTTTTGTGCCTGACAGGGTTGACGATGAGATGGGA
TGGGCGGGGATGTTCTGGCTTCCGCATGCAGAAGAGGCTAAATCCACTCTTCATGACCATCATCCGGAGTTGCTGCTTTA
TGGCCCGCTTACAAATTATTCAGACGAGTCGCTCTCCTTTCCGGGAGGTTTGTTTGTTTCAGTTGAGCAGTTACTTTCTC
TTGACGATGCAGTATGTGACCCGGAACAACCCTTTCTGCGCTGGAGTACCATAGCTGTTGACGCTTCGGTATTCGCCAGG
CTTCCCGGTGCAGCAATTGGTGACAACGGGTTTACCGATGAACTGTGGCAATACAGCGTGTCCGAACTTTTTTTAGGCCA
TGGAGAAGCAGAAAAAGAATACGTCGAGTTTGAAATGACACCTGACGGCGGCTGGGTAGCCCTTAAGTTCAGTCATAGGC
GAAAAAGGGCAAACGGATTTGAAATACCTGTACAGGAACCATGGGAACGCCATACGACCAGGTTTCATGATCCGAACCGT
TTCGGCATGACCTTTTCCTATTCACTGCTTGAACCATTTATTGTCGATCGCACTTTGGCAATGCAGTGCGCAGCAAGTAT
CGGCGAGTCTCGTTACGGTTTGTTTCCTTGGTGGAAAAGCCCGATCGGCACTCCGGATTTTCATCAGCCCGATCGATATT
ACCGGGTACAGCTCGGCTGA

Upstream 100 bases:

>100_bases
GGTATGGAAAATGATTTTTTCGGATTGTTAAACCCTTGTGCAATAGCTATGTTATCTTTTTGAAACACCTGGCAATCATA
CATCACAGACGCTGCCTCTC

Downstream 100 bases:

>100_bases
TTTTTTTTCTGACCAAACCACGTCTTTCCACGACAACTGGGCCGCGGGAAAGAGCGGTTTGGTTGGACAGGATTGCTCTT
AAAGGTCCGCAGCGGGCATT

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MENLSLPCPFLNNVHLSEKTYYQIGGKARLFALPESVRHIGDLLCWNRIHQFPLALMGMGSNTLFSSEPFEGIVISFENM
NRMFWISEHELFCEAGVENGAISEELLNKERGGGEWLYRLPGQIGSTVRMNARCFGGEIADVTSGIMTASISGALRWHRP
DEVFLGYKNTSIMDRSEIVVAVVLSFSAVKKHDEIQDLMESFEKERFDKHHFDYPSCGSTFKNNYEVGQSSGRIFEALGF
KGVREGGAQVSPYHANFIYNTGGATSSDVLRLAAKMKTVAATAIPAKLDLEVQCIGLHPKILLEACGVPFVPDRVDDEMG
WAGMFWLPHAEEAKSTLHDHHPELLLYGPLTNYSDESLSFPGGLFVSVEQLLSLDDAVCDPEQPFLRWSTIAVDASVFAR
LPGAAIGDNGFTDELWQYSVSELFLGHGEAEKEYVEFEMTPDGGWVALKFSHRRKRANGFEIPVQEPWERHTTRFHDPNR
FGMTFSYSLLEPFIVDRTLAMQCAASIGESRYGLFPWWKSPIGTPDFHQPDRYYRVQLG

Sequences:

>Translated_539_residues
MENLSLPCPFLNNVHLSEKTYYQIGGKARLFALPESVRHIGDLLCWNRIHQFPLALMGMGSNTLFSSEPFEGIVISFENM
NRMFWISEHELFCEAGVENGAISEELLNKERGGGEWLYRLPGQIGSTVRMNARCFGGEIADVTSGIMTASISGALRWHRP
DEVFLGYKNTSIMDRSEIVVAVVLSFSAVKKHDEIQDLMESFEKERFDKHHFDYPSCGSTFKNNYEVGQSSGRIFEALGF
KGVREGGAQVSPYHANFIYNTGGATSSDVLRLAAKMKTVAATAIPAKLDLEVQCIGLHPKILLEACGVPFVPDRVDDEMG
WAGMFWLPHAEEAKSTLHDHHPELLLYGPLTNYSDESLSFPGGLFVSVEQLLSLDDAVCDPEQPFLRWSTIAVDASVFAR
LPGAAIGDNGFTDELWQYSVSELFLGHGEAEKEYVEFEMTPDGGWVALKFSHRRKRANGFEIPVQEPWERHTTRFHDPNR
FGMTFSYSLLEPFIVDRTLAMQCAASIGESRYGLFPWWKSPIGTPDFHQPDRYYRVQLG
>Mature_539_residues
MENLSLPCPFLNNVHLSEKTYYQIGGKARLFALPESVRHIGDLLCWNRIHQFPLALMGMGSNTLFSSEPFEGIVISFENM
NRMFWISEHELFCEAGVENGAISEELLNKERGGGEWLYRLPGQIGSTVRMNARCFGGEIADVTSGIMTASISGALRWHRP
DEVFLGYKNTSIMDRSEIVVAVVLSFSAVKKHDEIQDLMESFEKERFDKHHFDYPSCGSTFKNNYEVGQSSGRIFEALGF
KGVREGGAQVSPYHANFIYNTGGATSSDVLRLAAKMKTVAATAIPAKLDLEVQCIGLHPKILLEACGVPFVPDRVDDEMG
WAGMFWLPHAEEAKSTLHDHHPELLLYGPLTNYSDESLSFPGGLFVSVEQLLSLDDAVCDPEQPFLRWSTIAVDASVFAR
LPGAAIGDNGFTDELWQYSVSELFLGHGEAEKEYVEFEMTPDGGWVALKFSHRRKRANGFEIPVQEPWERHTTRFHDPNR
FGMTFSYSLLEPFIVDRTLAMQCAASIGESRYGLFPWWKSPIGTPDFHQPDRYYRVQLG

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 60570; Mature: 60570

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLSLPCPFLNNVHLSEKTYYQIGGKARLFALPESVRHIGDLLCWNRIHQFPLALMGMG
CCCCCCCCCCCCCEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCHHEEECC
SNTLFSSEPFEGIVISFENMNRMFWISEHELFCEAGVENGAISEELLNKERGGGEWLYRL
CCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEC
PGQIGSTVRMNARCFGGEIADVTSGIMTASISGALRWHRPDEVFLGYKNTSIMDRSEIVV
CCCCCCEEEEECEECCCCHHHHHHHHHHEECCCEEEECCCCCEEEEECCCCCCCHHHHHH
AVVLSFSAVKKHDEIQDLMESFEKERFDKHHFDYPSCGSTFKNNYEVGQSSGRIFEALGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEHHHCC
KGVREGGAQVSPYHANFIYNTGGATSSDVLRLAAKMKTVAATAIPAKLDLEVQCIGLHPK
CHHHCCCCEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCHH
ILLEACGVPFVPDRVDDEMGWAGMFWLPHAEEAKSTLHDHHPELLLYGPLTNYSDESLSF
HHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
PGGLFVSVEQLLSLDDAVCDPEQPFLRWSTIAVDASVFARLPGAAIGDNGFTDELWQYSV
CCCHHEEHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHH
SELFLGHGEAEKEYVEFEMTPDGGWVALKFSHRRKRANGFEIPVQEPWERHTTRFHDPNR
HHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
FGMTFSYSLLEPFIVDRTLAMQCAASIGESRYGLFPWWKSPIGTPDFHQPDRYYRVQLG
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MENLSLPCPFLNNVHLSEKTYYQIGGKARLFALPESVRHIGDLLCWNRIHQFPLALMGMG
CCCCCCCCCCCCCEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCHHEEECC
SNTLFSSEPFEGIVISFENMNRMFWISEHELFCEAGVENGAISEELLNKERGGGEWLYRL
CCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEC
PGQIGSTVRMNARCFGGEIADVTSGIMTASISGALRWHRPDEVFLGYKNTSIMDRSEIVV
CCCCCCEEEEECEECCCCHHHHHHHHHHEECCCEEEECCCCCEEEEECCCCCCCHHHHHH
AVVLSFSAVKKHDEIQDLMESFEKERFDKHHFDYPSCGSTFKNNYEVGQSSGRIFEALGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEHHHCC
KGVREGGAQVSPYHANFIYNTGGATSSDVLRLAAKMKTVAATAIPAKLDLEVQCIGLHPK
CHHHCCCCEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCHH
ILLEACGVPFVPDRVDDEMGWAGMFWLPHAEEAKSTLHDHHPELLLYGPLTNYSDESLSF
HHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
PGGLFVSVEQLLSLDDAVCDPEQPFLRWSTIAVDASVFARLPGAAIGDNGFTDELWQYSV
CCCHHEEHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHH
SELFLGHGEAEKEYVEFEMTPDGGWVALKFSHRRKRANGFEIPVQEPWERHTTRFHDPNR
HHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
FGMTFSYSLLEPFIVDRTLAMQCAASIGESRYGLFPWWKSPIGTPDFHQPDRYYRVQLG
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA