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The map label for this gene is ppa [H]

Identifier: 119356998

GI number: 119356998

Start: 1333347

End: 1333880

Strand: Direct

Name: ppa [H]

Synonym: Cpha266_1182

Alternate gene names: 119356998

Gene position: 1333347-1333880 (Clockwise)

Preceding gene: 119356997

Following gene: 119357000

Centisome position: 42.55

GC content: 46.25

Gene sequence:

>534_bases
ATGAATTTTAATCCATGGCATCACGTCGAGATCGGAGAAGATCAGCCGAATATTGTCAACGCTATTATCGAGATTTCAAG
CGGAAGCAAGACCAAGTATGAGCTTGATAAAAAAACCGGTATGCTGAAGCTTGACCGGGTGCTGTTTTCTTCGGTGTTTT
ATCCGGCAAACTACGGATTTATCCCGAAAACTCTGGGTGATGATCATGACCCTCTTGATATTGTCGTTGTCTCCCAGTGC
CAGATTGTGCCAATGTGTATTGTGCGTGCGCGGGTCATCGGTGTGATGAGCATGATCGATCACGGCGAGGGCGACGACAA
GATTATTGCTGTTGCTGAAGACGACATGAGCATGAGCAATATTCACGACATCGATCAGCTTTCACCGCATTTTAACTCTG
AACTCAAGCACTTTTTTGAAGAGTACAAGGCTCTTGAGCACAAAACCGTGCTTGTCGAGGATTTTCTGAATGCGGCAGTA
GCCCGGCAGAGTATCCTGCATGCCATCGAAAACTACAACAAGGTCTATGCTTAG

Upstream 100 bases:

>100_bases
TCGAAACGTTGAAAATGTTTTCTTTTCTCTGCCGCCGTTAAAAAAAAAATGATATAATTGCACATGTTTTTTTATAACCC
ATTCACAGGTAGCCTTCACT

Downstream 100 bases:

>100_bases
GATATCGACCTGAAAGGTCTTATCTGTTCAGCGTTATTCCCGTTTTTCAGGCGATGAAAGCCCTCTTTTTCTTGAGAGTG
TTTTCATCGCTTTTTTTTTG

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNFNPWHHVEIGEDQPNIVNAIIEISSGSKTKYELDKKTGMLKLDRVLFSSVFYPANYGFIPKTLGDDHDPLDIVVVSQC
QIVPMCIVRARVIGVMSMIDHGEGDDKIIAVAEDDMSMSNIHDIDQLSPHFNSELKHFFEEYKALEHKTVLVEDFLNAAV
ARQSILHAIENYNKVYA

Sequences:

>Translated_177_residues
MNFNPWHHVEIGEDQPNIVNAIIEISSGSKTKYELDKKTGMLKLDRVLFSSVFYPANYGFIPKTLGDDHDPLDIVVVSQC
QIVPMCIVRARVIGVMSMIDHGEGDDKIIAVAEDDMSMSNIHDIDQLSPHFNSELKHFFEEYKALEHKTVLVEDFLNAAV
ARQSILHAIENYNKVYA
>Mature_177_residues
MNFNPWHHVEIGEDQPNIVNAIIEISSGSKTKYELDKKTGMLKLDRVLFSSVFYPANYGFIPKTLGDDHDPLDIVVVSQC
QIVPMCIVRARVIGVMSMIDHGEGDDKIIAVAEDDMSMSNIHDIDQLSPHFNSELKHFFEEYKALEHKTVLVEDFLNAAV
ARQSILHAIENYNKVYA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=171, Percent_Identity=28.6549707602339, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1790673, Length=168, Percent_Identity=36.9047619047619, Blast_Score=113, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71984880, Length=167, Percent_Identity=25.1497005988024, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984895, Length=167, Percent_Identity=25.1497005988024, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984883, Length=167, Percent_Identity=25.1497005988024, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71984889, Length=167, Percent_Identity=25.1497005988024, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319483, Length=158, Percent_Identity=26.5822784810127, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20047; Mature: 20047

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNPWHHVEIGEDQPNIVNAIIEISSGSKTKYELDKKTGMLKLDRVLFSSVFYPANYGF
CCCCCCEEEEECCCCCHHEEHEEECCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCCCCC
IPKTLGDDHDPLDIVVVSQCQIVPMCIVRARVIGVMSMIDHGEGDDKIIAVAEDDMSMSN
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
IHDIDQLSPHFNSELKHFFEEYKALEHKTVLVEDFLNAAVARQSILHAIENYNKVYA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFNPWHHVEIGEDQPNIVNAIIEISSGSKTKYELDKKTGMLKLDRVLFSSVFYPANYGF
CCCCCCEEEEECCCCCHHEEHEEECCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCCCCC
IPKTLGDDHDPLDIVVVSQCQIVPMCIVRARVIGVMSMIDHGEGDDKIIAVAEDDMSMSN
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
IHDIDQLSPHFNSELKHFFEEYKALEHKTVLVEDFLNAAVARQSILHAIENYNKVYA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA