Click here to switch to the map view.

The map label for this gene is dxs [C]

Identifier: 119356987

GI number: 119356987

Start: 1320113

End: 1321093

Strand: Direct

Name: dxs [C]

Synonym: Cpha266_1170

Alternate gene names: 119356987

Gene position: 1320113-1321093 (Clockwise)

Preceding gene: 119356979

Following gene: 119356988

Centisome position: 42.12

GC content: 49.54

Gene sequence:

>981_bases
ATGGGAGAAAATAACATCGAAGCGGCGGCTGCGCAATATGTTTCGCGGGGAAACAAGGCAACACGTACCGGATTTGGAGA
AGCCCTGCTTGAAATAGCAAGGGAGAACAATACTGTGGTCGGGTTATGCGCCGATCTTACAGGATCCCTGAACATGAATC
TTTTTCGGGATGCTTTTCCTGAAAGATTTATTCAGGCCGGAATTGCCGAAGCGAACATGATTTCAATGGCTGCCGGTCTT
GCAACCACAGGAAAAGTGCCATTTGCAGCAAGTTTCGCCGTGTTTGCCACCGGCAGGGTTTACGACCAGATTCGTCAGTC
GCTCTGCTATTCGAATCTCAATGTCAAGATTTGCGCCTCTCACGCAGGCCTTACTCTTGGCGAGGATGGCGCAACGCACC
AGATTCTTGAGGATATCGGACTGATGCGCGGTCTTCCGCGAATGACCGTTGTGGTTCCCTGTGATTACAGCGAAACCAAA
CGCGCAGTTAAGGCCATCGCAAAACGGTACGGTCCCGTTTATCTTCGGTTCGGCAGGCCGAACATTCCTGATTTTACGCT
TGATGAAGACGGCTTTGAAATCGGTAAATCCATAGAATTGCATCCCGGAAAGGATGTTACGGTTATTGCCTGCGGCATTA
TGGTCTGGAAGGCGCTTGAGGCGGCACGAATTCTTGAAAAAGAGGGCGTCGGAGTCAGGGTCATCAATATGCATACCATT
AAACCGATCGATACGCTTGCAATTGTCAGGGCAGCCAACGATACCGGCGCTATCGTTACGGCCGAAGAACACCAGATCTA
TAACGGCCTGGGAGATGCAGTGGCCAATGTTTGTGCCCGTAATATTCCCGTGCCGATCGAGATGGTAGGTGTTGAAGATC
AGTTTGGAGAATCCGGCAAGCCCGATGATCTTCTCATGAAATATAAACTGACAACCGAGGATATTCTCGATAAAATCTAT
ATCGCGTTACGCAGAAAGTAA

Upstream 100 bases:

>100_bases
TCTGTATGCTTATATTCAACTTTTATCATGATGACGGCGTTTTTTTTAGCACCTTACCCGGACGGAAATACTTTTTACAA
TTCAAGTTATTCAGGAAGTA

Downstream 100 bases:

>100_bases
ACTTTGCTCCGAAAAGAACGGAAAAAGAGGATATTTTCTTCAATAAACAAAGGAGAGCAAAAGCGATGGGAATGCCGAAT
TTAGGCGATATGATGAAACA

Product: transketolase subunit B

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MGENNIEAAAAQYVSRGNKATRTGFGEALLEIARENNTVVGLCADLTGSLNMNLFRDAFPERFIQAGIAEANMISMAAGL
ATTGKVPFAASFAVFATGRVYDQIRQSLCYSNLNVKICASHAGLTLGEDGATHQILEDIGLMRGLPRMTVVVPCDYSETK
RAVKAIAKRYGPVYLRFGRPNIPDFTLDEDGFEIGKSIELHPGKDVTVIACGIMVWKALEAARILEKEGVGVRVINMHTI
KPIDTLAIVRAANDTGAIVTAEEHQIYNGLGDAVANVCARNIPVPIEMVGVEDQFGESGKPDDLLMKYKLTTEDILDKIY
IALRRK

Sequences:

>Translated_326_residues
MGENNIEAAAAQYVSRGNKATRTGFGEALLEIARENNTVVGLCADLTGSLNMNLFRDAFPERFIQAGIAEANMISMAAGL
ATTGKVPFAASFAVFATGRVYDQIRQSLCYSNLNVKICASHAGLTLGEDGATHQILEDIGLMRGLPRMTVVVPCDYSETK
RAVKAIAKRYGPVYLRFGRPNIPDFTLDEDGFEIGKSIELHPGKDVTVIACGIMVWKALEAARILEKEGVGVRVINMHTI
KPIDTLAIVRAANDTGAIVTAEEHQIYNGLGDAVANVCARNIPVPIEMVGVEDQFGESGKPDDLLMKYKLTTEDILDKIY
IALRRK
>Mature_325_residues
GENNIEAAAAQYVSRGNKATRTGFGEALLEIARENNTVVGLCADLTGSLNMNLFRDAFPERFIQAGIAEANMISMAAGLA
TTGKVPFAASFAVFATGRVYDQIRQSLCYSNLNVKICASHAGLTLGEDGATHQILEDIGLMRGLPRMTVVVPCDYSETKR
AVKAIAKRYGPVYLRFGRPNIPDFTLDEDGFEIGKSIELHPGKDVTVIACGIMVWKALEAARILEKEGVGVRVINMHTIK
PIDTLAIVRAANDTGAIVTAEEHQIYNGLGDAVANVCARNIPVPIEMVGVEDQFGESGKPDDLLMKYKLTTEDILDKIYI
ALRRK

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=304, Percent_Identity=35.5263157894737, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4507521, Length=304, Percent_Identity=35.5263157894737, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI225637463, Length=306, Percent_Identity=38.562091503268, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI225637461, Length=306, Percent_Identity=38.562091503268, Blast_Score=177, Evalue=8e-45,
Organism=Homo sapiens, GI225637459, Length=306, Percent_Identity=38.562091503268, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI133778974, Length=313, Percent_Identity=33.8658146964856, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI1786622, Length=283, Percent_Identity=29.3286219081272, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788808, Length=353, Percent_Identity=26.628895184136, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994911, Length=265, Percent_Identity=25.2830188679245, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539652, Length=316, Percent_Identity=33.2278481012658, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=335, Percent_Identity=23.5820895522388, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645119, Length=323, Percent_Identity=33.7461300309598, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45551847, Length=323, Percent_Identity=33.7461300309598, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45550715, Length=323, Percent_Identity=33.7461300309598, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24666278, Length=330, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 35350; Mature: 35219

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGENNIEAAAAQYVSRGNKATRTGFGEALLEIARENNTVVGLCADLTGSLNMNLFRDAFP
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
ERFIQAGIAEANMISMAAGLATTGKVPFAASFAVFATGRVYDQIRQSLCYSNLNVKICAS
HHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEC
HAGLTLGEDGATHQILEDIGLMRGLPRMTVVVPCDYSETKRAVKAIAKRYGPVYLRFGRP
CCCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCC
NIPDFTLDEDGFEIGKSIELHPGKDVTVIACGIMVWKALEAARILEKEGVGVRVINMHTI
CCCCCCCCCCCHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KPIDTLAIVRAANDTGAIVTAEEHQIYNGLGDAVANVCARNIPVPIEMVGVEDQFGESGK
CCHHHEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCC
PDDLLMKYKLTTEDILDKIYIALRRK
CCCEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GENNIEAAAAQYVSRGNKATRTGFGEALLEIARENNTVVGLCADLTGSLNMNLFRDAFP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
ERFIQAGIAEANMISMAAGLATTGKVPFAASFAVFATGRVYDQIRQSLCYSNLNVKICAS
HHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEC
HAGLTLGEDGATHQILEDIGLMRGLPRMTVVVPCDYSETKRAVKAIAKRYGPVYLRFGRP
CCCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCC
NIPDFTLDEDGFEIGKSIELHPGKDVTVIACGIMVWKALEAARILEKEGVGVRVINMHTI
CCCCCCCCCCCHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KPIDTLAIVRAANDTGAIVTAEEHQIYNGLGDAVANVCARNIPVPIEMVGVEDQFGESGK
CCHHHEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCC
PDDLLMKYKLTTEDILDKIYIALRRK
CCCEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]