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The map label for this gene is cobO [H]

Identifier: 119356940

GI number: 119356940

Start: 1267003

End: 1267563

Strand: Direct

Name: cobO [H]

Synonym: Cpha266_1120

Alternate gene names: 119356940

Gene position: 1267003-1267563 (Clockwise)

Preceding gene: 119356939

Following gene: 119356941

Centisome position: 40.43

GC content: 54.72

Gene sequence:

>561_bases
ATGAACAGCCTCATCAACGAAACGACAGAGCGGATGAAACCTCGAAGGATTCTTCTTTTTACAGGAAACGGCAAAGGAAA
AAGCACAGCGGCGTTTGGCATGCTCGCCAGAGCGCTGGGTCACGGCATGAAAGCCAGAGTGATCCAGTTTGTAAAGTCTG
ATGATGCGGTAGGCGAGCAGCTTTTTTTCAGCCGGATTAACGAGGTGGAGTGGGATCATTTCGGCAGGGGATTTCTGCCG
CGCGATCGGCAGAGCCCGAAGATGGAGGAGCATAGAGCTGCCGCACGCTCAGGTCTTGACGCAGCGATTGCCGCCCTTGC
CTCTCCCGATTACGATTTTGTACTGCTTGATGAGCTTTGTTTTGCGCTTGGGCAGCATCTCATTTCCGCCGAACCGCTGC
TTGAAGCGCTTCGGTCGGCCGAGGATGGCAAGATTGTCGTGATGACAGGTCGCGACGCTCCGCAGGAGCTTATTGCCGTC
GCCGATACGGTTACTGAAATGGGCATGATCAAGCACGGGTTTGAACAGGGAATCCCGGCACAGATCGGGGTGGAAAACTG
A

Upstream 100 bases:

>100_bases
GCCCGGAAACGCTTCAGGAGAGTATCATCCTGATGCAGCTTACGTCAGCGACGTTTGCCGTAACAGGAATTGTTTTGTGT
CTCATTCTTGGGTATTTTTA

Downstream 100 bases:

>100_bases
GGCTGCATGAACCGTTCAAAAGAGTGTATCGATAATCGATTTACCGGAAAGCAGTATAAACAGTCGCGAGGCAAGCTGAT
TTTGTTTCTTCTTGCCGTTC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNSLINETTERMKPRRILLFTGNGKGKSTAAFGMLARALGHGMKARVIQFVKSDDAVGEQLFFSRINEVEWDHFGRGFLP
RDRQSPKMEEHRAAARSGLDAAIAALASPDYDFVLLDELCFALGQHLISAEPLLEALRSAEDGKIVVMTGRDAPQELIAV
ADTVTEMGMIKHGFEQGIPAQIGVEN

Sequences:

>Translated_186_residues
MNSLINETTERMKPRRILLFTGNGKGKSTAAFGMLARALGHGMKARVIQFVKSDDAVGEQLFFSRINEVEWDHFGRGFLP
RDRQSPKMEEHRAAARSGLDAAIAALASPDYDFVLLDELCFALGQHLISAEPLLEALRSAEDGKIVVMTGRDAPQELIAV
ADTVTEMGMIKHGFEQGIPAQIGVEN
>Mature_186_residues
MNSLINETTERMKPRRILLFTGNGKGKSTAAFGMLARALGHGMKARVIQFVKSDDAVGEQLFFSRINEVEWDHFGRGFLP
RDRQSPKMEEHRAAARSGLDAAIAALASPDYDFVLLDELCFALGQHLISAEPLLEALRSAEDGKIVVMTGRDAPQELIAV
ADTVTEMGMIKHGFEQGIPAQIGVEN

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=169, Percent_Identity=39.0532544378698, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20382; Mature: 20382

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLINETTERMKPRRILLFTGNGKGKSTAAFGMLARALGHGMKARVIQFVKSDDAVGEQ
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LFFSRINEVEWDHFGRGFLPRDRQSPKMEEHRAAARSGLDAAIAALASPDYDFVLLDELC
HHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHH
FALGQHLISAEPLLEALRSAEDGKIVVMTGRDAPQELIAVADTVTEMGMIKHGFEQGIPA
HHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
QIGVEN
CCCCCC
>Mature Secondary Structure
MNSLINETTERMKPRRILLFTGNGKGKSTAAFGMLARALGHGMKARVIQFVKSDDAVGEQ
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LFFSRINEVEWDHFGRGFLPRDRQSPKMEEHRAAARSGLDAAIAALASPDYDFVLLDELC
HHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHH
FALGQHLISAEPLLEALRSAEDGKIVVMTGRDAPQELIAVADTVTEMGMIKHGFEQGIPA
HHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
QIGVEN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]