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The map label for this gene is ycaL [C]

Identifier: 118581678

GI number: 118581678

Start: 3611309

End: 3612106

Strand: Direct

Name: ycaL [C]

Synonym: Ppro_3278

Alternate gene names: 118581678

Gene position: 3611309-3612106 (Clockwise)

Preceding gene: 118581677

Following gene: 118581682

Centisome position: 90.1

GC content: 61.78

Gene sequence:

>798_bases
ATGTCACGCCGCATATTCGCCATCATCGCCTGCCTGCTCTTGCTGAGCGCCTGCAGCACGGTACCGATCACCGGCAGATC
CCAACTCAACCTGATCCCCGGCTCTTCCATGCTCTCCATGAGCCTGCAGCAGTACGACCAGTTCCTGAAAGAGCACAAGC
TGAGCACCAACCAGGAGCAGACCCAGATGGTAAAACGGGTCGGGCTGAAAATACAGAATGCCGTCGAACGCTACTTCGCC
TCCAACGGCCTCAGCAGCCAGCTGGCCAACTACAAGTGGGAGTTCAACCTGGTGGAGGACAAACAGCTCAATGCCTGGTG
CATGCCGGGGGGCAAGGTGGTGGTCTACACCGGCATCCTGCCGGTGACCAAGGATGAAACCGGCCTGGCGGTGGTCATGG
GGCATGAGATAGCCCACGCCATTGCCGAGCATGGCAACGAGCGCATGAGCCAGGGGCTGATGGCCCAGATGGGTGGTGTG
GCCCTCTCCACGGCCCTGTCGACCCAACCGGCAGCGACGCAGCAACTCTGGATGGCAGCCTACGGCTTGGGTTCGCAGTA
CGGGGCGATCCTCCCCTACGGCCGCCTGCAGGAAAGCGAGGCCGATCACCTGGGGCTGATCTTCATGGCCATGGCCGGCT
ACTCCCCAAACGAAGCGGTGGGATTCTGGCAGCGCATGGCGGCCCAGAAGGGGGGAAATACGACACCGGAGTTTCTCAGC
ACCCACCCTGCGGACGCGACCCGCATCCAGAACATCCAGCGCCTGATACCCGAGGCGATGAAGTACTATCGACCCTGA

Upstream 100 bases:

>100_bases
CATCCGCGTTTCACATTGACGCCCTCATCATGGACACCCTCTCCCGATTGATGTATACACATCATAGCGAGCAAACACCG
CATTCACGAGGAGGTTACCC

Downstream 100 bases:

>100_bases
GACGCTCCCGGCGGCGCAGACGTCCGGTCAGGGGTGCTGCTCTCCACAAAAAAGCGGCGCCCCGGACACCGGTATGATGC
CTGCCCGCTCTCCCCGCTCC

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSRRIFAIIACLLLLSACSTVPITGRSQLNLIPGSSMLSMSLQQYDQFLKEHKLSTNQEQTQMVKRVGLKIQNAVERYFA
SNGLSSQLANYKWEFNLVEDKQLNAWCMPGGKVVVYTGILPVTKDETGLAVVMGHEIAHAIAEHGNERMSQGLMAQMGGV
ALSTALSTQPAATQQLWMAAYGLGSQYGAILPYGRLQESEADHLGLIFMAMAGYSPNEAVGFWQRMAAQKGGNTTPEFLS
THPADATRIQNIQRLIPEAMKYYRP

Sequences:

>Translated_265_residues
MSRRIFAIIACLLLLSACSTVPITGRSQLNLIPGSSMLSMSLQQYDQFLKEHKLSTNQEQTQMVKRVGLKIQNAVERYFA
SNGLSSQLANYKWEFNLVEDKQLNAWCMPGGKVVVYTGILPVTKDETGLAVVMGHEIAHAIAEHGNERMSQGLMAQMGGV
ALSTALSTQPAATQQLWMAAYGLGSQYGAILPYGRLQESEADHLGLIFMAMAGYSPNEAVGFWQRMAAQKGGNTTPEFLS
THPADATRIQNIQRLIPEAMKYYRP
>Mature_264_residues
SRRIFAIIACLLLLSACSTVPITGRSQLNLIPGSSMLSMSLQQYDQFLKEHKLSTNQEQTQMVKRVGLKIQNAVERYFAS
NGLSSQLANYKWEFNLVEDKQLNAWCMPGGKVVVYTGILPVTKDETGLAVVMGHEIAHAIAEHGNERMSQGLMAQMGGVA
LSTALSTQPAATQQLWMAAYGLGSQYGAILPYGRLQESEADHLGLIFMAMAGYSPNEAVGFWQRMAAQKGGNTTPEFLST
HPADATRIQNIQRLIPEAMKYYRP

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TPR repeat [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=263, Percent_Identity=28.8973384030418, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI87081800, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788840, Length=167, Percent_Identity=26.3473053892216, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322940, Length=277, Percent_Identity=29.2418772563177, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48; PF07720 TPR_3 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 29148; Mature: 29017

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIFAIIACLLLLSACSTVPITGRSQLNLIPGSSMLSMSLQQYDQFLKEHKLSTNQEQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHH
TQMVKRVGLKIQNAVERYFASNGLSSQLANYKWEFNLVEDKQLNAWCMPGGKVVVYTGIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCEEECCCCCEEEEECCE
PVTKDETGLAVVMGHEIAHAIAEHGNERMSQGLMAQMGGVALSTALSTQPAATQQLWMAA
EECCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHH
YGLGSQYGAILPYGRLQESEADHLGLIFMAMAGYSPNEAVGFWQRMAAQKGGNTTPEFLS
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
THPADATRIQNIQRLIPEAMKYYRP
CCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRRIFAIIACLLLLSACSTVPITGRSQLNLIPGSSMLSMSLQQYDQFLKEHKLSTNQEQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHH
TQMVKRVGLKIQNAVERYFASNGLSSQLANYKWEFNLVEDKQLNAWCMPGGKVVVYTGIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCEEECCCCCEEEEECCE
PVTKDETGLAVVMGHEIAHAIAEHGNERMSQGLMAQMGGVALSTALSTQPAATQQLWMAA
EECCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHH
YGLGSQYGAILPYGRLQESEADHLGLIFMAMAGYSPNEAVGFWQRMAAQKGGNTTPEFLS
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
THPADATRIQNIQRLIPEAMKYYRP
CCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]