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The map label for this gene is tolC [C]

Identifier: 118581045

GI number: 118581045

Start: 2859777

End: 2861051

Strand: Direct

Name: tolC [C]

Synonym: Ppro_2633

Alternate gene names: 118581045

Gene position: 2859777-2861051 (Clockwise)

Preceding gene: 118581044

Following gene: 118581046

Centisome position: 71.35

GC content: 64.63

Gene sequence:

>1275_bases
ATGAAGTTCCAACCTGTTAGCCTGGCCCTCGTCATCCTGTTAATCTTGGCGTCCCATGCCCGGGGGGCTGCGCTTTCCCT
GTCGGACTGCCTCGAAAAAGCGGAAAAGCACAACCCCGAACTGCGAACGCTGGCCTGGGAACCGATCATGGCGGAACAGA
ACGTAGCCCAGGCCGTATCGGCACGCTATCCCCGCCTGGACGGCCGGGTCGGCTATACCATGCAAAAGGATCCCCAGGCC
GCGATCATCATGGGACGCGTGGCCGAATTGCAGGATTCCGACTATGCCCACGGCGGACTGGAGGCGCTCTACACCATCTA
CGACTTCGGCAAACGGGAGGCGCGCATCAGCCAGGCCCGCGCCACTGCCGACGCCATACGCAGCAGGTACGATGCCCGGC
GCACGGACGTTTCCCTACAGGTTATCGAGGTCTACTTCGGCATCCTTGAGGGGATGCAGCTGGTAGAGGCGGCACGGGAC
GAGATCACCCAGGTGGAGCAGCACCGCCGCATGGCCCAGGCCCTGTTCGACGAGGGGGTGGTCACCCGCAACGACATCCT
GCAGGCCGATGTGCGCCTGGCATCGGCCCGCCAGACCCTGCTCTCCCGGAACAACAGCCTGGACAACACCTGGCTGCGGC
TGAACTACCTGACCGGCAGCGCCCCCTCATTCCGAGGCGAGTTGAGCAGCGAGGCAGGTATTGGCGACAGGACCGACGCT
CCCACCGGAGACAGCGCTGCCCTGACCAAGCGCCCCGAGATTCTTGCCCTGCGCAAGGGGGTGGATGCCAGCCAGGCCGA
ACTCAAGGAGAGCAGGAGCGCCTATCTCCCCGAACTGTACACCCGCCTGGCCCTGGAATACGTGGATAACAGCAAGTACC
GCGAACAGACCATCATGTCTGCCGGCGTGGGACTCAAGGTAAACCTGTTCGACGGTTTCGCCACAACCGCGGCCAGGGAC
AGGGCGGCGCGGAACCTCTCCCGGAGCCAGGACCTGCTGCGCCAGGGCGAGACGCAGGTGCAACTGGAGATATCCACGGC
CCGCAACGACCTGCGGGTTGCGGGTGAGCGGATCACCGTGACCGAGACCGCCATTCGCCAGAGCCAGGAGAACCTGCGCA
TCAACCACGAGCGCTATAAAGAGCGGGTCGGCACGGCCACCGAGGTGCTGGACGCACAGACCCTGCTGACCCAGACCAGA
ACCGACTATTTCCGGGCCCTTTTCGACCGTCAGGTGGCGGCCGCCCGCCTGAGGCGCGCCCTGGGAGAACTGTAG

Upstream 100 bases:

>100_bases
GCCCAACGCGCCCGGGCCAGGATCACCAGCTGCCTGAACGGGCAGGAAGCCAATGAGCTGACACGGATGCTGGAGCTGAT
GCGCGCCGACCGGAGGTTCT

Downstream 100 bases:

>100_bases
CCAAGAACAGTATTGTACTGTCCGATGGAGGGACATGAATCATGACGGAAGAGACGCACACGCCGGGCCAGAGCCAGGCG
GAGCCGGAAGCGGCCAGGGC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Protein; Outer Membrane Efflux Family Protein; Type I Secretion Outer Membrane Protein; Outer Membrane Macrolide Efflux Protein; RND Family Efflux Pump Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC Family; Efflux System Outer Membrane Protein; Outer Membrane Protein-Like; Type I Secretion Outer Membrane Protein lC; Type I Secretion Outer Membrane Protein lc Family; Secretion Protein; Outer Membrane Protein CyaE

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKFQPVSLALVILLILASHARGAALSLSDCLEKAEKHNPELRTLAWEPIMAEQNVAQAVSARYPRLDGRVGYTMQKDPQA
AIIMGRVAELQDSDYAHGGLEALYTIYDFGKREARISQARATADAIRSRYDARRTDVSLQVIEVYFGILEGMQLVEAARD
EITQVEQHRRMAQALFDEGVVTRNDILQADVRLASARQTLLSRNNSLDNTWLRLNYLTGSAPSFRGELSSEAGIGDRTDA
PTGDSAALTKRPEILALRKGVDASQAELKESRSAYLPELYTRLALEYVDNSKYREQTIMSAGVGLKVNLFDGFATTAARD
RAARNLSRSQDLLRQGETQVQLEISTARNDLRVAGERITVTETAIRQSQENLRINHERYKERVGTATEVLDAQTLLTQTR
TDYFRALFDRQVAAARLRRALGEL

Sequences:

>Translated_424_residues
MKFQPVSLALVILLILASHARGAALSLSDCLEKAEKHNPELRTLAWEPIMAEQNVAQAVSARYPRLDGRVGYTMQKDPQA
AIIMGRVAELQDSDYAHGGLEALYTIYDFGKREARISQARATADAIRSRYDARRTDVSLQVIEVYFGILEGMQLVEAARD
EITQVEQHRRMAQALFDEGVVTRNDILQADVRLASARQTLLSRNNSLDNTWLRLNYLTGSAPSFRGELSSEAGIGDRTDA
PTGDSAALTKRPEILALRKGVDASQAELKESRSAYLPELYTRLALEYVDNSKYREQTIMSAGVGLKVNLFDGFATTAARD
RAARNLSRSQDLLRQGETQVQLEISTARNDLRVAGERITVTETAIRQSQENLRINHERYKERVGTATEVLDAQTLLTQTR
TDYFRALFDRQVAAARLRRALGEL
>Mature_424_residues
MKFQPVSLALVILLILASHARGAALSLSDCLEKAEKHNPELRTLAWEPIMAEQNVAQAVSARYPRLDGRVGYTMQKDPQA
AIIMGRVAELQDSDYAHGGLEALYTIYDFGKREARISQARATADAIRSRYDARRTDVSLQVIEVYFGILEGMQLVEAARD
EITQVEQHRRMAQALFDEGVVTRNDILQADVRLASARQTLLSRNNSLDNTWLRLNYLTGSAPSFRGELSSEAGIGDRTDA
PTGDSAALTKRPEILALRKGVDASQAELKESRSAYLPELYTRLALEYVDNSKYREQTIMSAGVGLKVNLFDGFATTAARD
RAARNLSRSQDLLRQGETQVQLEISTARNDLRVAGERITVTETAIRQSQENLRINHERYKERVGTATEVLDAQTLLTQTR
TDYFRALFDRQVAAARLRRALGEL

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47361; Mature: 47361

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFQPVSLALVILLILASHARGAALSLSDCLEKAEKHNPELRTLAWEPIMAEQNVAQAVS
CCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
ARYPRLDGRVGYTMQKDPQAAIIMGRVAELQDSDYAHGGLEALYTIYDFGKREARISQAR
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
ATADAIRSRYDARRTDVSLQVIEVYFGILEGMQLVEAARDEITQVEQHRRMAQALFDEGV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTRNDILQADVRLASARQTLLSRNNSLDNTWLRLNYLTGSAPSFRGELSSEAGIGDRTDA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
PTGDSAALTKRPEILALRKGVDASQAELKESRSAYLPELYTRLALEYVDNSKYREQTIMS
CCCCCCHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGVGLKVNLFDGFATTAARDRAARNLSRSQDLLRQGETQVQLEISTARNDLRVAGERITV
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHCCCEEEE
TETAIRQSQENLRINHERYKERVGTATEVLDAQTLLTQTRTDYFRALFDRQVAAARLRRA
HHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEL
HCCC
>Mature Secondary Structure
MKFQPVSLALVILLILASHARGAALSLSDCLEKAEKHNPELRTLAWEPIMAEQNVAQAVS
CCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
ARYPRLDGRVGYTMQKDPQAAIIMGRVAELQDSDYAHGGLEALYTIYDFGKREARISQAR
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
ATADAIRSRYDARRTDVSLQVIEVYFGILEGMQLVEAARDEITQVEQHRRMAQALFDEGV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTRNDILQADVRLASARQTLLSRNNSLDNTWLRLNYLTGSAPSFRGELSSEAGIGDRTDA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
PTGDSAALTKRPEILALRKGVDASQAELKESRSAYLPELYTRLALEYVDNSKYREQTIMS
CCCCCCHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGVGLKVNLFDGFATTAARDRAARNLSRSQDLLRQGETQVQLEISTARNDLRVAGERITV
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHCCCEEEE
TETAIRQSQENLRINHERYKERVGTATEVLDAQTLLTQTRTDYFRALFDRQVAAARLRRA
HHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA