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The map label for this gene is moaC

Identifier: 118578976

GI number: 118578976

Start: 575211

End: 575693

Strand: Direct

Name: moaC

Synonym: Ppro_0537

Alternate gene names: 118578976

Gene position: 575211-575693 (Clockwise)

Preceding gene: 118578975

Following gene: 118578977

Centisome position: 14.35

GC content: 65.63

Gene sequence:

>483_bases
ATGAATTTCAATCACTTTGATGAATCAGGCAATGCCGTGATGGTGGATGTGAGCCACAAACAGCCGACCCTGCGTACGGC
GGTGGCGGCGGCCCGGGTGGGCATGTCGCCGGAGCTTCTGGCAGCCATCCGCGAGGGGGGCATGGCCAAGGGGGATGTGC
TGGGGGTGGCGCGCCTGGCCGGCATCATGGCCGCCAAGAAGACCCCGGACCTGATCCCGCTCTCCCATCCCCTGGCGATC
CACTCCGTTGCCGTGGATTATGAACTGGACAGTGGGGCCGGCACCATCCAGGTGCGTTGCACGGTGCGGGCCCTGGAGCG
CACCGGCGTGGAGATGGAAGCCATGACCGGCGCCTCCCTGGCGGCCCTGACCATCTACGACATGTGCAAGGGGAGCGACA
AGTCCATCACCATCGGCGACATCCGGCTGCTCTACAAGGAGGGCGGCAAGAGCGGCGTGTACCGGCGGGAGGAGGGGCAA
TGA

Upstream 100 bases:

>100_bases
GCTGCGCCATCGACAAGAAGCAGTTCGAACAGTACCTGCCGGCTGACAGCGCCAAGGCGGACTAAGCCCGGAATACGAAG
ATAACTATGCGAGGAATATT

Downstream 100 bases:

>100_bases
GGGCGGCGATCCTGACCCTGAGCGACAAGGGAGCCCGTGGGGAACGTGTGGACGCGAGCGGCCCGGCCCTGGCGAGCTGG
CTGGCCGAGCACGGGGTGGA

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MNFNHFDESGNAVMVDVSHKQPTLRTAVAAARVGMSPELLAAIREGGMAKGDVLGVARLAGIMAAKKTPDLIPLSHPLAI
HSVAVDYELDSGAGTIQVRCTVRALERTGVEMEAMTGASLAALTIYDMCKGSDKSITIGDIRLLYKEGGKSGVYRREEGQ

Sequences:

>Translated_160_residues
MNFNHFDESGNAVMVDVSHKQPTLRTAVAAARVGMSPELLAAIREGGMAKGDVLGVARLAGIMAAKKTPDLIPLSHPLAI
HSVAVDYELDSGAGTIQVRCTVRALERTGVEMEAMTGASLAALTIYDMCKGSDKSITIGDIRLLYKEGGKSGVYRREEGQ
>Mature_160_residues
MNFNHFDESGNAVMVDVSHKQPTLRTAVAAARVGMSPELLAAIREGGMAKGDVLGVARLAGIMAAKKTPDLIPLSHPLAI
HSVAVDYELDSGAGTIQVRCTVRALERTGVEMEAMTGASLAALTIYDMCKGSDKSITIGDIRLLYKEGGKSGVYRREEGQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=50, Blast_Score=145, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32566331, Length=158, Percent_Identity=39.873417721519, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=47.1698113207547, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=48.2993197278912, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_PELPD (A1ALE8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900226.1
- ProteinModelPortal:   A1ALE8
- SMR:   A1ALE8
- STRING:   A1ALE8
- GeneID:   4572546
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0537
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   A1ALE8
- ProtClustDB:   CLSK828946
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16960; Mature: 16960

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNHFDESGNAVMVDVSHKQPTLRTAVAAARVGMSPELLAAIREGGMAKGDVLGVARLA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHH
GIMAAKKTPDLIPLSHPLAIHSVAVDYELDSGAGTIQVRCTVRALERTGVEMEAMTGASL
HHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEEEEHHHCCCEEEECCCCCH
AALTIYDMCKGSDKSITIGDIRLLYKEGGKSGVYRREEGQ
HHHHHHHHHCCCCCEEEEHHEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNFNHFDESGNAVMVDVSHKQPTLRTAVAAARVGMSPELLAAIREGGMAKGDVLGVARLA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHH
GIMAAKKTPDLIPLSHPLAIHSVAVDYELDSGAGTIQVRCTVRALERTGVEMEAMTGASL
HHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEEEEHHHCCCEEEECCCCCH
AALTIYDMCKGSDKSITIGDIRLLYKEGGKSGVYRREEGQ
HHHHHHHHHCCCCCEEEEHHEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA