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The map label for this gene is bepD [H]

Identifier: 118578852

GI number: 118578852

Start: 423671

End: 424894

Strand: Direct

Name: bepD [H]

Synonym: Ppro_0410

Alternate gene names: 118578852

Gene position: 423671-424894 (Clockwise)

Preceding gene: 118578850

Following gene: 118578853

Centisome position: 10.57

GC content: 62.75

Gene sequence:

>1224_bases
ATGAAGAGTCTCAGGAGCGTCCGCACATTGTTCTGGTCGACCGGTTATGCCGGGCGGTGCTTCACGGCAGCCGCCTGCTT
GGTTGCACTGCTGGCAAACGGCTGCGCCAAGAAGGAAAAGCCTGTCGCGTTACCTCCGCCGGCGGTCGAGATTGTCCAGG
TCATTGCCAAAGACACGCCGATTATCTCCGAATACGTGGCACAGACCCAGAGTTCGCAGCAGGTGAGCATCCAGGCCCGG
GTAAATGGCTTCCTGGAAAAGCGGGCCTATACCGAGGGGAGTATTGTGAAGGCGGGTACCGTCCTCTTCCTGATGGACAA
GAAACCGTTTCAGGCCCAGGTGGATGCCGCGAGCGCGGCACTGGATCGGCAAAAGGCCGCCATGAAGACGGCCCGCCTCA
ATCTTGATCGCACCAAGCCCCTGACTGAAAAGAACGCCCTCTCCAAGAAGGACCTGGATGACGCCACCGGCGCCTATGAA
TCGGCGGCAGCGGCTGTGGAGGCGGCCAAAGCCCAGCTGCTGACGGCGCGGCTCAACCTCTCCTACTGCACCATAACCTC
CCCGGTGAACGGCATCACCAGCGCCGCCCTGCAGCAGGAAGGCGCCTACATCAACACGCAGAACAGCCTGCTGACCACCG
TGGCGGTCCTCTCACCCATCTGGGTCAACTTCAGTTTGTCGGAAAACGAGTTGAAGGAATATAGCGATCAGATTGCCAAG
GGACAGATCCGCCCCCCCAAAGGGCAGAATTACGAGATCGAGATCGTGCAGGTTGACGGCTCCATCTTCCCCCACTCCGG
CCGCATCACCTTCGCCGACCCCTCCTTCAACCCCCAGACCGGCACCTTCCTGCTGCGGGCCAGCGTCAACAACCCCAAAG
GAGTCCTGCGTCCGAACCAGTACGTACGCGCCCGCATCAAGGGGGCCATCAGGCCCAACGCCATCCTGGTGCCGCAACGG
GCGGTGCAGCAGGGGGCCAAGGGGCACTTCGTCTGGGTCGTGGACAGGGAGAACAAGGCGGAATCCAGGCCGGTGGTGGT
GGGTGAACTGATGGGCAACGACTGGTTCATCAGCGAGGGGCTCAAGGCCGGCGAAAAGGTGGTGGTGGACGGCGGCATGA
CCCTGCGGCCGGGCATCCAAGTGGTGGTGAAGCAGGCTGGCGCCTCCCAGAGCGGCCCCGCGGCCGCCGAACCGAAACCG
ACCCCGGCGAAGAAGGCCGACTGA

Upstream 100 bases:

>100_bases
GAGCAGCTTTTGTCCAGTTCGCACAATGGATTCAGCACGCCGAAATCCAGCAAACTGGTTTTCTCTTGTTTTAACTACTG
GCATCTCATGGGGGTAGAGC

Downstream 100 bases:

>100_bases
CAGAGGAGGGGCAGCATGTTTTCCAAGTTTTTCATCGAACGGCCGATCTTCGCCACGGTCATCTCCCTGATCATCGTCAT
CGCCGGCCTGGTGGCGATGA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKSLRSVRTLFWSTGYAGRCFTAAACLVALLANGCAKKEKPVALPPPAVEIVQVIAKDTPIISEYVAQTQSSQQVSIQAR
VNGFLEKRAYTEGSIVKAGTVLFLMDKKPFQAQVDAASAALDRQKAAMKTARLNLDRTKPLTEKNALSKKDLDDATGAYE
SAAAAVEAAKAQLLTARLNLSYCTITSPVNGITSAALQQEGAYINTQNSLLTTVAVLSPIWVNFSLSENELKEYSDQIAK
GQIRPPKGQNYEIEIVQVDGSIFPHSGRITFADPSFNPQTGTFLLRASVNNPKGVLRPNQYVRARIKGAIRPNAILVPQR
AVQQGAKGHFVWVVDRENKAESRPVVVGELMGNDWFISEGLKAGEKVVVDGGMTLRPGIQVVVKQAGASQSGPAAAEPKP
TPAKKAD

Sequences:

>Translated_407_residues
MKSLRSVRTLFWSTGYAGRCFTAAACLVALLANGCAKKEKPVALPPPAVEIVQVIAKDTPIISEYVAQTQSSQQVSIQAR
VNGFLEKRAYTEGSIVKAGTVLFLMDKKPFQAQVDAASAALDRQKAAMKTARLNLDRTKPLTEKNALSKKDLDDATGAYE
SAAAAVEAAKAQLLTARLNLSYCTITSPVNGITSAALQQEGAYINTQNSLLTTVAVLSPIWVNFSLSENELKEYSDQIAK
GQIRPPKGQNYEIEIVQVDGSIFPHSGRITFADPSFNPQTGTFLLRASVNNPKGVLRPNQYVRARIKGAIRPNAILVPQR
AVQQGAKGHFVWVVDRENKAESRPVVVGELMGNDWFISEGLKAGEKVVVDGGMTLRPGIQVVVKQAGASQSGPAAAEPKP
TPAKKAD
>Mature_407_residues
MKSLRSVRTLFWSTGYAGRCFTAAACLVALLANGCAKKEKPVALPPPAVEIVQVIAKDTPIISEYVAQTQSSQQVSIQAR
VNGFLEKRAYTEGSIVKAGTVLFLMDKKPFQAQVDAASAALDRQKAAMKTARLNLDRTKPLTEKNALSKKDLDDATGAYE
SAAAAVEAAKAQLLTARLNLSYCTITSPVNGITSAALQQEGAYINTQNSLLTTVAVLSPIWVNFSLSENELKEYSDQIAK
GQIRPPKGQNYEIEIVQVDGSIFPHSGRITFADPSFNPQTGTFLLRASVNNPKGVLRPNQYVRARIKGAIRPNAILVPQR
AVQQGAKGHFVWVVDRENKAESRPVVVGELMGNDWFISEGLKAGEKVVVDGGMTLRPGIQVVVKQAGASQSGPAAAEPKP
TPAKKAD

Specific function: Involved in resistance to several unrelated toxic compounds, such as dyes, detergents and antibiotics [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=393, Percent_Identity=34.6055979643766, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1789665, Length=355, Percent_Identity=34.0845070422535, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789929, Length=354, Percent_Identity=30.225988700565, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082036, Length=313, Percent_Identity=29.7124600638978, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081796, Length=318, Percent_Identity=26.1006289308176, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43700; Mature: 43700

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLRSVRTLFWSTGYAGRCFTAAACLVALLANGCAKKEKPVALPPPAVEIVQVIAKDTP
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
IISEYVAQTQSSQQVSIQARVNGFLEKRAYTEGSIVKAGTVLFLMDKKPFQAQVDAASAA
HHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCHHHHHHHHHH
LDRQKAAMKTARLNLDRTKPLTEKNALSKKDLDDATGAYESAAAAVEAAKAQLLTARLNL
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHEEEEECC
SYCTITSPVNGITSAALQQEGAYINTQNSLLTTVAVLSPIWVNFSLSENELKEYSDQIAK
EEEEECCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
GQIRPPKGQNYEIEIVQVDGSIFPHSGRITFADPSFNPQTGTFLLRASVNNPKGVLRPNQ
CCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCH
YVRARIKGAIRPNAILVPQRAVQQGAKGHFVWVVDRENKAESRPVVVGELMGNDWFISEG
HHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEECCC
LKAGEKVVVDGGMTLRPGIQVVVKQAGASQSGPAAAEPKPTPAKKAD
CCCCCEEEEECCCEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSLRSVRTLFWSTGYAGRCFTAAACLVALLANGCAKKEKPVALPPPAVEIVQVIAKDTP
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
IISEYVAQTQSSQQVSIQARVNGFLEKRAYTEGSIVKAGTVLFLMDKKPFQAQVDAASAA
HHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCHHHHHHHHHH
LDRQKAAMKTARLNLDRTKPLTEKNALSKKDLDDATGAYESAAAAVEAAKAQLLTARLNL
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHEEEEECC
SYCTITSPVNGITSAALQQEGAYINTQNSLLTTVAVLSPIWVNFSLSENELKEYSDQIAK
EEEEECCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHC
GQIRPPKGQNYEIEIVQVDGSIFPHSGRITFADPSFNPQTGTFLLRASVNNPKGVLRPNQ
CCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCH
YVRARIKGAIRPNAILVPQRAVQQGAKGHFVWVVDRENKAESRPVVVGELMGNDWFISEG
HHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEECCC
LKAGEKVVVDGGMTLRPGIQVVVKQAGASQSGPAAAEPKPTPAKKAD
CCCCCEEEEECCCEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]