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The map label for this gene is plsC [H]

Identifier: 118578822

GI number: 118578822

Start: 393584

End: 394288

Strand: Direct

Name: plsC [H]

Synonym: Ppro_0380

Alternate gene names: 118578822

Gene position: 393584-394288 (Clockwise)

Preceding gene: 118578821

Following gene: 118578823

Centisome position: 9.82

GC content: 62.41

Gene sequence:

>705_bases
ATGGTTCGCGCGTACCTGTTTCTGTCGCTGTTTATCCCATTCACCTTTTTCTGCGCGCTGAGCGCGCTGCTTGGTACGCT
GCTGGATGCCAGCGGCAGGGTCTTTTCCGCCCATGCCCGCTTCTGGGGGCGCGGCTCCCTTTTTCTGGCCGGTACACGGG
TCAGGCTGACCGGTGTCGAGCATCTTCCTTCCGGGCCGGTCATTTTCATGAGCAATCACCAGAGCGGCTTCGACATACCG
ACCCTGCTGGCGGTTCTGCCGCTGGAGACCTGCTGGATCGCCAAGAAAGAGCTGTTCGACATTCCGGTGTTCGGGAGCGC
CATGGGGCGCGGCGGCTATATCCCGCTGGACCGTCGCGATGCCCACCGGGCATTGAAGAGCCTGGAGATGGCCGTCAAGG
TCGTCCGCTCCGGAAGGAGTCTGCTCATTTTCCCCGAGGGTACCCGCTCCATGGATTTTCGGCTGCTCCCCTTCAAGCGG
GGCGGCTTCAAACTTGCGCTCCAGGCTGGAGTGCCGGTGGTACCGCTAACCATCAACGGCAGCGGCCGGGTGAATCCGGC
TGGCAGCATCCGGCTCTACCCCGGCCGGATTTCCGTTACCCTGCACCGGCCGATCATGCCGCCAGCCGGTTTTTCTCGTG
CCCAAGCCGAAGTCCTGTTGCGGGAACGGGTGCATGATGCCATTTCATCGGTGCTGGAGATCTGA

Upstream 100 bases:

>100_bases
CCTGCAGCCACGGATGTTTCGCAAAAACAGCCCATTATTTCGTTTGACTCACAAAGGGGAAACAAGGTAGGTTGAACTCC
CACTACTCCGGAGTTTCCGC

Downstream 100 bases:

>100_bases
CGCATGCATGCCGGATTACTCTACATTCCGTTGGTCCTCGCCGGTCTGGCCGCCATTGCCTGGGGGCTTCCGGCGGCGCA
CCGCCTGCGCCCTCCCCTGG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MVRAYLFLSLFIPFTFFCALSALLGTLLDASGRVFSAHARFWGRGSLFLAGTRVRLTGVEHLPSGPVIFMSNHQSGFDIP
TLLAVLPLETCWIAKKELFDIPVFGSAMGRGGYIPLDRRDAHRALKSLEMAVKVVRSGRSLLIFPEGTRSMDFRLLPFKR
GGFKLALQAGVPVVPLTINGSGRVNPAGSIRLYPGRISVTLHRPIMPPAGFSRAQAEVLLRERVHDAISSVLEI

Sequences:

>Translated_234_residues
MVRAYLFLSLFIPFTFFCALSALLGTLLDASGRVFSAHARFWGRGSLFLAGTRVRLTGVEHLPSGPVIFMSNHQSGFDIP
TLLAVLPLETCWIAKKELFDIPVFGSAMGRGGYIPLDRRDAHRALKSLEMAVKVVRSGRSLLIFPEGTRSMDFRLLPFKR
GGFKLALQAGVPVVPLTINGSGRVNPAGSIRLYPGRISVTLHRPIMPPAGFSRAQAEVLLRERVHDAISSVLEI
>Mature_234_residues
MVRAYLFLSLFIPFTFFCALSALLGTLLDASGRVFSAHARFWGRGSLFLAGTRVRLTGVEHLPSGPVIFMSNHQSGFDIP
TLLAVLPLETCWIAKKELFDIPVFGSAMGRGGYIPLDRRDAHRALKSLEMAVKVVRSGRSLLIFPEGTRSMDFRLLPFKR
GGFKLALQAGVPVVPLTINGSGRVNPAGSIRLYPGRISVTLHRPIMPPAGFSRAQAEVLLRERVHDAISSVLEI

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=189, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI15100175, Length=189, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI6041665, Length=232, Percent_Identity=28.8793103448276, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1789395, Length=142, Percent_Identity=34.5070422535211, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564032, Length=158, Percent_Identity=27.2151898734177, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17568319, Length=153, Percent_Identity=30.0653594771242, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=175, Percent_Identity=34.2857142857143, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641614, Length=200, Percent_Identity=30, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641612, Length=200, Percent_Identity=30, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364648, Length=179, Percent_Identity=30.7262569832402, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582856, Length=179, Percent_Identity=30.7262569832402, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582854, Length=179, Percent_Identity=30.7262569832402, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 25641; Mature: 25641

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRAYLFLSLFIPFTFFCALSALLGTLLDASGRVFSAHARFWGRGSLFLAGTRVRLTGVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEEEECEEEEEECC
HLPSGPVIFMSNHQSGFDIPTLLAVLPLETCWIAKKELFDIPVFGSAMGRGGYIPLDRRD
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
AHRALKSLEMAVKVVRSGRSLLIFPEGTRSMDFRLLPFKRGGFKLALQAGVPVVPLTING
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEEECCCCEEEEEECC
SGRVNPAGSIRLYPGRISVTLHRPIMPPAGFSRAQAEVLLRERVHDAISSVLEI
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRAYLFLSLFIPFTFFCALSALLGTLLDASGRVFSAHARFWGRGSLFLAGTRVRLTGVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEEEECEEEEEECC
HLPSGPVIFMSNHQSGFDIPTLLAVLPLETCWIAKKELFDIPVFGSAMGRGGYIPLDRRD
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
AHRALKSLEMAVKVVRSGRSLLIFPEGTRSMDFRLLPFKRGGFKLALQAGVPVVPLTING
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEEECCCCEEEEEECC
SGRVNPAGSIRLYPGRISVTLHRPIMPPAGFSRAQAEVLLRERVHDAISSVLEI
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]