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The map label for this gene is xerC

Identifier: 118578727

GI number: 118578727

Start: 281900

End: 282808

Strand: Direct

Name: xerC

Synonym: Ppro_0285

Alternate gene names: 118578727

Gene position: 281900-282808 (Clockwise)

Preceding gene: 118578726

Following gene: 118578730

Centisome position: 7.03

GC content: 65.02

Gene sequence:

>909_bases
ATGCAGCCCCTGATGGAACAGATCCGCGCTTTCCGTCTCCACCTGGAAACGGAGCGCAACCTGTCGCCCCACACCCTGGC
CGCCTATGATCGCGACCTGCGCCAGTTCGCGGCTTTTGTTGCTGCCGAAATGGGAGACTCTGCCACGGCCGAGGACGTGG
ACCATCTGCTGCTGCGGCGCTACCTGGCCCAACTGGGCACGCAGATCAGGAAGAGCTCCCAGGGGCGCAAGCTGGCCGCT
ATCCGCAGCTTCTACCGCCACCTGCTCAGGCTGGGGAGTGTCTCCCGGAATCCGGCCGAACTGATCGCCACCCCCAAGCG
TGAGCAGCGACTCCCCTTTCACCTGGACATCGATCAGGCCACCGCCCTGATGGAGACTCCCACGGAAGAAGAAAATTACG
GGCTGCGTGACAGGGCCATTCTGGAGACGCTCTACTCCAGCGGGCTGCGCGTATCGGAGCTGACCGGTCTTGCAATCCGC
GACATCAATCTTGCGGGCGGAATGCTGCGGGTGATGGGCAAGGGGGGCAAGGAGCGTATCGTGCCGCTGGGGAGCAGGGC
GGTCCGGGCCATCCAGGAGTACCTGGACAGCCGGGGAGGGGGTACGGCAACCGCCCCCCTGTTTCTCAACAGCCGGGGTG
ATCGGATCAACCGCCGCAGCGTCGCCCGCATCGTGGATGCCCATGTGCACGAGATAGCGGCCTTCAAACACATCTCCCCC
CACACCCTGCGCCACACCTTCGCCACCCACATGCTGGAGGGGGGCGCGGACCTGCGTGCCATCCAGGAATTGTTGGGCCA
CGCCTCCCTCTCCACCACCCAGAAGTACACCCACGTCAGTCTCGACCGCCTGATGGAGGTCTACGACAAGGCCCACCCCA
AGGCCCGGACTCCGGAGCCGGAGGAGTAG

Upstream 100 bases:

>100_bases
CAAGACCCTGACCTACAAGCAGGACTGGGTCTACCGGGACGTGGACGACAAGAAGAGCTGGCGGGTGAAGAGCGCGCTAC
CCCCCTTCGACTGAGCAACA

Downstream 100 bases:

>100_bases
AATAACGTTCATTCACATCTCTGCCGGACATGAAAAGGGGAATCGCTCACGTAGCTGGTTCCCCTCTTTTTTTCTCAGAT
CTGTGCCGCTGTCTGCGGGG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQPLMEQIRAFRLHLETERNLSPHTLAAYDRDLRQFAAFVAAEMGDSATAEDVDHLLLRRYLAQLGTQIRKSSQGRKLAA
IRSFYRHLLRLGSVSRNPAELIATPKREQRLPFHLDIDQATALMETPTEEENYGLRDRAILETLYSSGLRVSELTGLAIR
DINLAGGMLRVMGKGGKERIVPLGSRAVRAIQEYLDSRGGGTATAPLFLNSRGDRINRRSVARIVDAHVHEIAAFKHISP
HTLRHTFATHMLEGGADLRAIQELLGHASLSTTQKYTHVSLDRLMEVYDKAHPKARTPEPEE

Sequences:

>Translated_302_residues
MQPLMEQIRAFRLHLETERNLSPHTLAAYDRDLRQFAAFVAAEMGDSATAEDVDHLLLRRYLAQLGTQIRKSSQGRKLAA
IRSFYRHLLRLGSVSRNPAELIATPKREQRLPFHLDIDQATALMETPTEEENYGLRDRAILETLYSSGLRVSELTGLAIR
DINLAGGMLRVMGKGGKERIVPLGSRAVRAIQEYLDSRGGGTATAPLFLNSRGDRINRRSVARIVDAHVHEIAAFKHISP
HTLRHTFATHMLEGGADLRAIQELLGHASLSTTQKYTHVSLDRLMEVYDKAHPKARTPEPEE
>Mature_302_residues
MQPLMEQIRAFRLHLETERNLSPHTLAAYDRDLRQFAAFVAAEMGDSATAEDVDHLLLRRYLAQLGTQIRKSSQGRKLAA
IRSFYRHLLRLGSVSRNPAELIATPKREQRLPFHLDIDQATALMETPTEEENYGLRDRAILETLYSSGLRVSELTGLAIR
DINLAGGMLRVMGKGGKERIVPLGSRAVRAIQEYLDSRGGGTATAPLFLNSRGDRINRRSVARIVDAHVHEIAAFKHISP
HTLRHTFATHMLEGGADLRAIQELLGHASLSTTQKYTHVSLDRLMEVYDKAHPKARTPEPEE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=39.5973154362416, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789261, Length=302, Percent_Identity=39.7350993377483, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=30.8641975308642, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790767, Length=164, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_PELPD (A1AKP9)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_899977.1
- ProteinModelPortal:   A1AKP9
- SMR:   A1AKP9
- STRING:   A1AKP9
- GeneID:   4574878
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0285
- eggNOG:   COG4974
- HOGENOM:   HBG727654
- OMA:   RDINLAG
- PhylomeDB:   A1AKP9
- ProtClustDB:   CLSK827873
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33880; Mature: 33880

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: ACT_SITE 150-150 ACT_SITE 174-174 ACT_SITE 241-241 ACT_SITE 244-244 ACT_SITE 267-267 ACT_SITE 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLMEQIRAFRLHLETERNLSPHTLAAYDRDLRQFAAFVAAEMGDSATAEDVDHLLLRR
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YLAQLGTQIRKSSQGRKLAAIRSFYRHLLRLGSVSRNPAELIATPKREQRLPFHLDIDQA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCCCCEEECHHHH
TALMETPTEEENYGLRDRAILETLYSSGLRVSELTGLAIRDINLAGGMLRVMGKGGKERI
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHEEECHHHCHHHHHHCCCCCCCC
VPLGSRAVRAIQEYLDSRGGGTATAPLFLNSRGDRINRRSVARIVDAHVHEIAAFKHISP
CCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHTFATHMLEGGADLRAIQELLGHASLSTTQKYTHVSLDRLMEVYDKAHPKARTPEP
HHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EE
CC
>Mature Secondary Structure
MQPLMEQIRAFRLHLETERNLSPHTLAAYDRDLRQFAAFVAAEMGDSATAEDVDHLLLRR
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YLAQLGTQIRKSSQGRKLAAIRSFYRHLLRLGSVSRNPAELIATPKREQRLPFHLDIDQA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCCCCEEECHHHH
TALMETPTEEENYGLRDRAILETLYSSGLRVSELTGLAIRDINLAGGMLRVMGKGGKERI
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHEEECHHHCHHHHHHCCCCCCCC
VPLGSRAVRAIQEYLDSRGGGTATAPLFLNSRGDRINRRSVARIVDAHVHEIAAFKHISP
CCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHTFATHMLEGGADLRAIQELLGHASLSTTQKYTHVSLDRLMEVYDKAHPKARTPEP
HHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA